These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

151 related articles for article (PubMed ID: 27629993)

  • 1. Effect of Partially Fluorinated N-Alkyl-Substituted Piperidine-2-carboxamides on Pharmacologically Relevant Properties.
    Vorberg R; Trapp N; Zimmerli D; Wagner B; Fischer H; Kratochwil NA; Kansy M; Carreira EM; Müller K
    ChemMedChem; 2016 Oct; 11(19):2216-2239. PubMed ID: 27629993
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Modulation of Pharmacologically Relevant Properties of Piperidine Derivatives by Functional Groups in an Equatorial or Axial β-Position to the Amino Group.
    Schnider P; Dolente C; Stalder H; Martin RE; Reinmüller V; Marty R; Wyss Gramberg C; Wagner B; Fischer H; Alker AM; Müller K
    Chembiochem; 2020 Jan; 21(1-2):212-234. PubMed ID: 31491045
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and pharmacological evaluation of 1-alkyl-N-[2-ethyl-2-(4-fluorophenyl)butyl]piperidine-4-carboxamide derivatives as novel antihypertensive agents.
    Watanuki S; Matsuura K; Tomura Y; Okada M; Okazaki T; Ohta M; Tsukamoto S
    Bioorg Med Chem; 2011 Sep; 19(18):5628-38. PubMed ID: 21875808
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design of fluorinated 5-HT(4)R antagonists: influence of the basicity and lipophilicity toward the 5-HT(4)R binding affinities.
    Fontenelle CQ; Wang Z; Fossey C; Cailly T; Linclau B; Fabis F
    Bioorg Med Chem; 2013 Dec; 21(23):7529-38. PubMed ID: 24128816
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Fluorination Patterning: A Study of Structural Motifs That Impact Physicochemical Properties of Relevance to Drug Discovery.
    Huchet QA; Kuhn B; Wagner B; Kratochwil NA; Fischer H; Kansy M; Zimmerli D; Carreira EM; Müller K
    J Med Chem; 2015 Nov; 58(22):9041-60. PubMed ID: 26523333
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and NMDA receptor affinity of fluorinated dioxadrol analogues.
    Banerjee A; Schepmann D; Wünsch B
    Bioorg Med Chem; 2010 Jun; 18(11):4095-102. PubMed ID: 20451396
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Fluorinated benzyloxyphenyl piperidine-4-carboxamides with dual function against thrombosis: inhibitors of factor Xa and platelet aggregation.
    de Candia M; Liantonio F; Carotti A; De Cristofaro R; Altomare C
    J Med Chem; 2009 Feb; 52(4):1018-28. PubMed ID: 19193009
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Impact of Fluoroalkyl Substituents on the Physicochemical Properties of Saturated Heterocyclic Amines.
    Melnykov KP; Tavlui O; Skreminskiy A; Kuchkovska YO; Grygorenko OO
    Chemistry; 2022 Oct; 28(55):e202201601. PubMed ID: 35699162
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Stereoselective access to fluorinated and non-fluorinated quaternary piperidines: synthesis of pipecolic acid and iminosugar derivatives.
    Fustero S; Albert L; Mateu N; Chiva G; Miró J; González J; Aceña JL
    Chemistry; 2012 Mar; 18(12):3753-64. PubMed ID: 22334380
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and structure-activity relationships of a new series of 2alpha-substituted trans-4,5-dimethyl-4-(3-hydroxyphenyl)piperidine as mu-selective opioid antagonists.
    Le Bourdonnec B; Goodman AJ; Michaut M; Ye HF; Graczyk TM; Belanger S; DeHaven RN; Dolle RE
    Bioorg Med Chem Lett; 2006 Feb; 16(4):864-8. PubMed ID: 16298525
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Aqueous Instability of δ-Fluorobutylpiperidines.
    Vorberg R; Carreira EM; Müller K
    ChemMedChem; 2017 Mar; 12(6):431-437. PubMed ID: 28139081
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Enantioselective synthesis and antioxidant activity of 3,4,5-substituted piperidine derivatives.
    Kim JH; Shyam PK; Kim MJ; Lee HJ; Lee JT; Jang HY
    Bioorg Med Chem Lett; 2016 Jul; 26(13):3119-3121. PubMed ID: 27177825
    [TBL] [Abstract][Full Text] [Related]  

  • 13. N-[omega-(Tetralin-1-yl)alkyl] derivatives of 3,3-dimethylpiperidine are highly potent and selective sigma1 or sigma2 ligands.
    Berardi F; Santoro S; Perrone R; Tortorella V; Govoni S; Lucchi L
    J Med Chem; 1998 Oct; 41(21):3940-7. PubMed ID: 9767631
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Fluorination methods in drug discovery.
    Yerien DE; Bonesi S; Postigo A
    Org Biomol Chem; 2016 Sep; 14(36):8398-427. PubMed ID: 27506398
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Melanocortin subtype 4 receptor agonists: structure-activity relationships about the 4-alkyl piperidine core.
    Sebhat IK; Lai Y; Barakat K; Ye Z; Tang R; Kalyani RN; Vongs A; Macneil T; Weinberg DH; Cabello MA; Maroto M; Teran A; Fong TM; Van der Ploeg LH; Patchett AA; Nargund RP
    Bioorg Med Chem Lett; 2007 Oct; 17(20):5720-3. PubMed ID: 17768046
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Potent heteroarylpiperidine and carboxyphenylpiperidine 1-alkyl-cyclopentane carboxamide CCR2 antagonists.
    Pasternak A; Goble SD; Vicario PP; Di Salvo J; Ayala JM; Struthers M; DeMartino JA; Mills SG; Yang L
    Bioorg Med Chem Lett; 2008 Feb; 18(3):994-8. PubMed ID: 18164199
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rapid development of piperidine carboxamides as potent and selective anaplastic lymphoma kinase inhibitors.
    Bryan MC; Whittington DA; Doherty EM; Falsey JR; Cheng AC; Emkey R; Brake RL; Lewis RT
    J Med Chem; 2012 Feb; 55(4):1698-705. PubMed ID: 22263917
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Improving selectivity preserving affinity: new piperidine-4-carboxamide derivatives as effective sigma-1-ligands.
    Zampieri D; Laurini E; Vio L; Fermeglia M; Pricl S; Wünsch B; Schepmann D; Mamolo MG
    Eur J Med Chem; 2015 Jan; 90():797-808. PubMed ID: 25528334
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Skipped Fluorination Motifs: Synthesis of Building Blocks and Comparison of Lipophilicity Trends with Vicinal and Isolated Fluorination Motifs.
    Troup RI; Jeffries B; Saudain RE; Georgiou E; Fish J; Scott JS; Chiarparin E; Fallan C; Linclau B
    J Org Chem; 2021 Jan; 86(2):1882-1900. PubMed ID: 33400526
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biphenyloxy-alkyl-piperidine and azepane derivatives as histamine H
    Łażewska D; Kaleta M; Schwed JS; Karcz T; Mogilski S; Latacz G; Olejarz A; Siwek A; Kubacka M; Lubelska A; Honkisz E; Handzlik J; Filipek B; Stark H; Kieć-Kononowicz K
    Bioorg Med Chem; 2017 Oct; 25(20):5341-5354. PubMed ID: 28797771
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.