These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
4. Self-assembly of FUS through its low-complexity domain contributes to neurodegeneration. Matsumoto T; Matsukawa K; Watanabe N; Kishino Y; Kunugi H; Ihara R; Wakabayashi T; Hashimoto T; Iwatsubo T Hum Mol Genet; 2018 Apr; 27(8):1353-1365. PubMed ID: 29425337 [TBL] [Abstract][Full Text] [Related]
5. A Drosophila model of ALS reveals a partial loss of function of causative human PFN1 mutants. Wu CH; Giampetruzzi A; Tran H; Fallini C; Gao FB; Landers JE Hum Mol Genet; 2017 Jun; 26(11):2146-2155. PubMed ID: 28379367 [TBL] [Abstract][Full Text] [Related]
6. Mutant PFN1 causes ALS phenotypes and progressive motor neuron degeneration in mice by a gain of toxicity. Yang C; Danielson EW; Qiao T; Metterville J; Brown RH; Landers JE; Xu Z Proc Natl Acad Sci U S A; 2016 Oct; 113(41):E6209-E6218. PubMed ID: 27681617 [TBL] [Abstract][Full Text] [Related]
7. Targeting RACK1 to alleviate TDP-43 and FUS proteinopathy-mediated suppression of protein translation and neurodegeneration. Zhao B; Cowan CM; Coutts JA; Christy DD; Saraph A; Hsueh SCC; Plotkin SS; Mackenzie IR; Kaplan JM; Cashman NR Acta Neuropathol Commun; 2023 Dec; 11(1):200. PubMed ID: 38111057 [TBL] [Abstract][Full Text] [Related]
8. Pathological Modification of TDP-43 in Amyotrophic Lateral Sclerosis with SOD1 Mutations. Jeon GS; Shim YM; Lee DY; Kim JS; Kang M; Ahn SH; Shin JY; Geum D; Hong YH; Sung JJ Mol Neurobiol; 2019 Mar; 56(3):2007-2021. PubMed ID: 29982983 [TBL] [Abstract][Full Text] [Related]
9. Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis. Wu CH; Fallini C; Ticozzi N; Keagle PJ; Sapp PC; Piotrowska K; Lowe P; Koppers M; McKenna-Yasek D; Baron DM; Kost JE; Gonzalez-Perez P; Fox AD; Adams J; Taroni F; Tiloca C; Leclerc AL; Chafe SC; Mangroo D; Moore MJ; Zitzewitz JA; Xu ZS; van den Berg LH; Glass JD; Siciliano G; Cirulli ET; Goldstein DB; Salachas F; Meininger V; Rossoll W; Ratti A; Gellera C; Bosco DA; Bassell GJ; Silani V; Drory VE; Brown RH; Landers JE Nature; 2012 Aug; 488(7412):499-503. PubMed ID: 22801503 [TBL] [Abstract][Full Text] [Related]
10. Profilin 1 mutants form aggregates that induce accumulation of prion-like TDP-43. Tanaka Y; Hasegawa M Prion; 2016 Jul; 10(4):283-9. PubMed ID: 27432186 [TBL] [Abstract][Full Text] [Related]
11. Monocytes of patients with amyotrophic lateral sclerosis linked to gene mutations display altered TDP-43 subcellular distribution. De Marco G; Lomartire A; Calvo A; Risso A; De Luca E; Mostert M; Mandrioli J; Caponnetto C; Borghero G; Manera U; Canosa A; Moglia C; Restagno G; Fini N; Tarella C; Giordana MT; Rinaudo MT; Chiò A Neuropathol Appl Neurobiol; 2017 Feb; 43(2):133-153. PubMed ID: 27178390 [TBL] [Abstract][Full Text] [Related]
13. A novel phosphorylation site mutation in profilin 1 revealed in a large screen of US, Nordic, and German amyotrophic lateral sclerosis/frontotemporal dementia cohorts. Ingre C; Landers JE; Rizik N; Volk AE; Akimoto C; Birve A; Hübers A; Keagle PJ; Piotrowska K; Press R; Andersen PM; Ludolph AC; Weishaupt JH Neurobiol Aging; 2013 Jun; 34(6):1708.e1-6. PubMed ID: 23141414 [TBL] [Abstract][Full Text] [Related]
14. A Drosophila model of FUS-related neurodegeneration reveals genetic interaction between FUS and TDP-43. Lanson NA; Maltare A; King H; Smith R; Kim JH; Taylor JP; Lloyd TE; Pandey UB Hum Mol Genet; 2011 Jul; 20(13):2510-23. PubMed ID: 21487023 [TBL] [Abstract][Full Text] [Related]
15. Mutation analysis and immunopathological studies of PFN1 in familial and sporadic amyotrophic lateral sclerosis. Yang S; Fifita JA; Williams KL; Warraich ST; Pamphlett R; Nicholson GA; Blair IP Neurobiol Aging; 2013 Sep; 34(9):2235.e7-10. PubMed ID: 23635659 [TBL] [Abstract][Full Text] [Related]
16. FUS and TARDBP but not SOD1 interact in genetic models of amyotrophic lateral sclerosis. Kabashi E; Bercier V; Lissouba A; Liao M; Brustein E; Rouleau GA; Drapeau P PLoS Genet; 2011 Aug; 7(8):e1002214. PubMed ID: 21829392 [TBL] [Abstract][Full Text] [Related]
17. Profilin-1 mutations are rare in patients with amyotrophic lateral sclerosis and frontotemporal dementia. van Blitterswijk M; Baker MC; Bieniek KF; Knopman DS; Josephs KA; Boeve B; Caselli R; Wszolek ZK; Petersen R; Graff-Radford NR; Boylan KB; Dickson DW; Rademakers R Amyotroph Lateral Scler Frontotemporal Degener; 2013 Sep; 14(5-6):463-9. PubMed ID: 23634771 [TBL] [Abstract][Full Text] [Related]
18. Motor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosis. Estes PS; Daniel SG; McCallum AP; Boehringer AV; Sukhina AS; Zwick RA; Zarnescu DC Dis Model Mech; 2013 May; 6(3):721-33. PubMed ID: 23471911 [TBL] [Abstract][Full Text] [Related]
19. Human TDP-43 and FUS selectively affect motor neuron maturation and survival in a murine cell model of ALS by non-cell-autonomous mechanisms. Wächter N; Storch A; Hermann A Amyotroph Lateral Scler Frontotemporal Degener; 2015; 16(7-8):431-41. PubMed ID: 26174443 [TBL] [Abstract][Full Text] [Related]
20. Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS. Mitchell JC; Constable R; So E; Vance C; Scotter E; Glover L; Hortobagyi T; Arnold ES; Ling SC; McAlonis M; Da Cruz S; Polymenidou M; Tessarolo L; Cleveland DW; Shaw CE Acta Neuropathol Commun; 2015 Jun; 3():36. PubMed ID: 26108367 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]