BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

257 related articles for article (PubMed ID: 27634046)

  • 1. Male Subfertility Induced by Heterozygous Expression of Catalytically Inactive Glutathione Peroxidase 4 Is Rescued in Vivo by Systemic Inactivation of the Alox15 Gene.
    Brütsch SH; Rademacher M; Roth SR; Müller K; Eder S; Viertel D; Franz C; Kuhn H; Borchert A
    J Biol Chem; 2016 Nov; 291(45):23578-23588. PubMed ID: 27634046
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Expression of inactive glutathione peroxidase 4 leads to embryonic lethality, and inactivation of the Alox15 gene does not rescue such knock-in mice.
    Brütsch SH; Wang CC; Li L; Stender H; Neziroglu N; Richter C; Kuhn H; Borchert A
    Antioxid Redox Signal; 2015 Feb; 22(4):281-93. PubMed ID: 25313597
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Expression of a Catalytically Inactive Mutant Form of Glutathione Peroxidase 4 (Gpx4) Confers a Dominant-negative Effect in Male Fertility.
    Ingold I; Aichler M; Yefremova E; Roveri A; Buday K; Doll S; Tasdemir A; Hoffard N; Wurst W; Walch A; Ursini F; Friedmann Angeli JP; Conrad M
    J Biol Chem; 2015 Jun; 290(23):14668-78. PubMed ID: 25922076
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Unbalanced Expression of Glutathione Peroxidase 4 and Arachidonate 15-Lipoxygenase Affects Acrosome Reaction and In Vitro Fertilization.
    Soria-Tiedemann M; Michel G; Urban I; Aldrovandi M; O'Donnell VB; Stehling S; Kuhn H; Borchert A
    Int J Mol Sci; 2022 Aug; 23(17):. PubMed ID: 36077303
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Altered epididymal sperm maturation and cytoplasmic droplet migration in subfertile male Alox15 mice.
    Moore K; Lovercamp K; Feng D; Antelman J; Sutovsky M; Manandhar G; van Leyen K; Safranski T; Sutovsky P
    Cell Tissue Res; 2010 Jun; 340(3):569-81. PubMed ID: 20449608
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differential cell death decisions in the testis: evidence for an exclusive window of ferroptosis in round spermatids.
    Bromfield EG; Walters JLH; Cafe SL; Bernstein IR; Stanger SJ; Anderson AL; Aitken RJ; McLaughlin EA; Dun MD; Gadella BM; Nixon B
    Mol Hum Reprod; 2019 May; 25(5):241-256. PubMed ID: 30865280
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Expression Silencing of Glutathione Peroxidase 4 in Mouse Erythroleukemia Cells Delays In Vitro Erythropoiesis.
    Rademacher M; Kuhn H; Borchert A
    Int J Mol Sci; 2021 Jul; 22(15):. PubMed ID: 34360557
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Depletion of selenoprotein GPx4 in spermatocytes causes male infertility in mice.
    Imai H; Hakkaku N; Iwamoto R; Suzuki J; Suzuki T; Tajima Y; Konishi K; Minami S; Ichinose S; Ishizaka K; Shioda S; Arata S; Nishimura M; Naito S; Nakagawa Y
    J Biol Chem; 2009 Nov; 284(47):32522-32. PubMed ID: 19783653
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inverse regulation of lipid-peroxidizing and hydroperoxyl lipid-reducing enzymes by interleukins 4 and 13.
    Schnurr K; Borchert A; Kuhn H
    FASEB J; 1999 Jan; 13(1):143-54. PubMed ID: 9872939
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Absence of glutathione peroxidase 4 affects tumor angiogenesis through increased 12/15-lipoxygenase activity.
    Schneider M; Wortmann M; Mandal PK; Arpornchayanon W; Jannasch K; Alves F; Strieth S; Conrad M; Beck H
    Neoplasia; 2010 Mar; 12(3):254-63. PubMed ID: 20234819
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-mediated cell death.
    Seiler A; Schneider M; Förster H; Roth S; Wirth EK; Culmsee C; Plesnila N; Kremmer E; Rådmark O; Wurst W; Bornkamm GW; Schweizer U; Conrad M
    Cell Metab; 2008 Sep; 8(3):237-48. PubMed ID: 18762024
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Female mice carrying a defective Alox15 gene are protected from experimental colitis via sustained maintenance of the intestinal epithelial barrier function.
    Kroschwald S; Chiu CY; Heydeck D; Rohwer N; Gehring T; Seifert U; Lux A; Rothe M; Weylandt KH; Kuhn H
    Biochim Biophys Acta Mol Cell Biol Lipids; 2018 Aug; 1863(8):866-880. PubMed ID: 29702245
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The role of phospholipid hydroperoxide glutathione peroxidase isoforms in murine embryogenesis.
    Borchert A; Wang CC; Ufer C; Schiebel H; Savaskan NE; Kuhn H
    J Biol Chem; 2006 Jul; 281(28):19655-64. PubMed ID: 16684775
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of arachidonate 15-lipoxygenase prevents 4-hydroxynonenal-induced protein damage in male germ cells.
    Bromfield EG; Mihalas BP; Dun MD; Aitken RJ; McLaughlin EA; Walters JL; Nixon B
    Biol Reprod; 2017 Mar; 96(3):598-609. PubMed ID: 28339608
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Knock-in mice expressing a humanized arachidonic acid 15-lipoxygenase (Alox15) carry a partly dysfunctional erythropoietic system.
    Reisch F; Heydeck D; Schäfer M; Rothe M; Yang J; Stehling S; Püschel GP; Kuhn H
    Cell Mol Biol Lett; 2023 Nov; 28(1):97. PubMed ID: 38030974
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mitochondrial glutathione peroxidase 4 disruption causes male infertility.
    Schneider M; Förster H; Boersma A; Seiler A; Wehnes H; Sinowatz F; Neumüller C; Deutsch MJ; Walch A; Hrabé de Angelis M; Wurst W; Ursini F; Roveri A; Maleszewski M; Maiorino M; Conrad M
    FASEB J; 2009 Sep; 23(9):3233-42. PubMed ID: 19417079
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Omega-3 fatty acids protect from colitis via an Alox15-derived eicosanoid.
    Rohwer N; Chiu CY; Huang D; Smyl C; Rothe M; Rund KM; Helge Schebb N; Kühn H; Weylandt KH
    FASEB J; 2021 Apr; 35(4):e21491. PubMed ID: 33710695
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Long-chain fatty acid triglyceride (TG) metabolism disorder impairs male fertility: a study using adipose triglyceride lipase deficient mice.
    Masaki H; Kim N; Nakamura H; Kumasawa K; Kamata E; Hirano KI; Kimura T
    Mol Hum Reprod; 2017 Jul; 23(7):452-460. PubMed ID: 28510703
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Platelet-type 12-lipoxygenase deletion provokes a compensatory 12/15-lipoxygenase increase that exacerbates oxidative stress in mouse islet β cells.
    Conteh AM; Reissaus CA; Hernandez-Perez M; Nakshatri S; Anderson RM; Mirmira RG; Tersey SA; Linnemann AK
    J Biol Chem; 2019 Apr; 294(16):6612-6620. PubMed ID: 30792307
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Short form glutathione peroxidase 4 is the essential isoform required for survival and somatic mitochondrial functions.
    Liang H; Yoo SE; Na R; Walter CA; Richardson A; Ran Q
    J Biol Chem; 2009 Nov; 284(45):30836-44. PubMed ID: 19744930
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.