BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

185 related articles for article (PubMed ID: 27638859)

  • 1. ATM Expression Predicts Veliparib and Irinotecan Sensitivity in Gastric Cancer by Mediating P53-Independent Regulation of Cell Cycle and Apoptosis.
    Subhash VV; Tan SH; Yeo MS; Yan FL; Peethala PC; Liem N; Krishnan V; Yong WP
    Mol Cancer Ther; 2016 Dec; 15(12):3087-3096. PubMed ID: 27638859
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Low ATM protein expression and depletion of p53 correlates with olaparib sensitivity in gastric cancer cell lines.
    Kubota E; Williamson CT; Ye R; Elegbede A; Peterson L; Lees-Miller SP; Bebb DG
    Cell Cycle; 2014; 13(13):2129-37. PubMed ID: 24841718
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cellular effects of CPT-11 on colon carcinoma cells: dependence on p53 and hMLH1 status.
    Magrini R; Bhonde MR; Hanski ML; Notter M; Scherübl H; Boland CR; Zeitz M; Hanski C
    Int J Cancer; 2002 Sep; 101(1):23-31. PubMed ID: 12209584
    [TBL] [Abstract][Full Text] [Related]  

  • 4. AZD6738, A Novel Oral Inhibitor of ATR, Induces Synthetic Lethality with ATM Deficiency in Gastric Cancer Cells.
    Min A; Im SA; Jang H; Kim S; Lee M; Kim DK; Yang Y; Kim HJ; Lee KH; Kim JW; Kim TY; Oh DY; Brown J; Lau A; O'Connor MJ; Bang YJ
    Mol Cancer Ther; 2017 Apr; 16(4):566-577. PubMed ID: 28138034
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Radiosensitization by irinotecan is attributed to G2/M phase arrest, followed by enhanced apoptosis, probably through the ATM/Chk/Cdc25C/Cdc2 pathway in p53-mutant colorectal cancer cells.
    Wang Y; Yang L; Zhang J; Zhou M; Shen L; Deng W; Liang L; Hu R; Yang W; Yao Y; Zhang H; Zhang Z
    Int J Oncol; 2018 Oct; 53(4):1667-1680. PubMed ID: 30085332
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The dual EGFR/HER-2 tyrosine kinase inhibitor lapatinib sensitizes colon and gastric cancer cells to the irinotecan active metabolite SN-38.
    LaBonte MJ; Manegold PC; Wilson PM; Fazzone W; Louie SG; Lenz HJ; Ladner RD
    Int J Cancer; 2009 Dec; 125(12):2957-69. PubMed ID: 19536776
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Elimination of hepatic metastases of colon cancer cells via p53-independent cross-talk between irinotecan and Apo2 ligand/TRAIL.
    Ravi R; Jain AJ; Schulick RD; Pham V; Prouser TS; Allen H; Mayer EG; Yu H; Pardoll DM; Ashkenazi A; Bedi A
    Cancer Res; 2004 Dec; 64(24):9105-14. PubMed ID: 15604280
    [TBL] [Abstract][Full Text] [Related]  

  • 8. S-phase checkpoints regulate Apo2 ligand/TRAIL and CPT-11-induced apoptosis of prostate cancer cells.
    Ray S; Shyam S; Fraizer GC; Almasan A
    Mol Cancer Ther; 2007 Apr; 6(4):1368-78. PubMed ID: 17431115
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The PARP inhibitor ABT-888 synergizes irinotecan treatment of colon cancer cell lines.
    Davidson D; Wang Y; Aloyz R; Panasci L
    Invest New Drugs; 2013 Apr; 31(2):461-8. PubMed ID: 23054213
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Alteration of the ATM gene occurs in gastric cancer cell lines and primary tumors associated with cellular response to DNA damage.
    Zhang L; Jia G; Li WM; Guo RF; Cui JT; Yang L; Lu YY
    Mutat Res; 2004 Jan; 557(1):41-51. PubMed ID: 14706517
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of autophagy in chemoresistance: regulation of the ATM-mediated DNA-damage signaling pathway through activation of DNA-PKcs and PARP-1.
    Yoon JH; Ahn SG; Lee BH; Jung SH; Oh SH
    Biochem Pharmacol; 2012 Mar; 83(6):747-57. PubMed ID: 22226932
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mechanism of beta-carotene-induced apoptosis of gastric cancer cells: involvement of ataxia-telangiectasia-mutated.
    Jang SH; Lim JW; Kim H
    Ann N Y Acad Sci; 2009 Aug; 1171():156-62. PubMed ID: 19723050
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Deletion of 11q in Neuroblastomas Drives Sensitivity to PARP Inhibition.
    Sanmartín E; Muñoz L; Piqueras M; Sirerol JA; Berlanga P; Cañete A; Castel V; Font de Mora J
    Clin Cancer Res; 2017 Nov; 23(22):6875-6887. PubMed ID: 28830922
    [No Abstract]   [Full Text] [Related]  

  • 14. 2-Hydroxyethyl methacrylate-induced apoptosis through the ATM- and p53-dependent intrinsic mitochondrial pathway.
    Schweikl H; Petzel C; Bolay C; Hiller KA; Buchalla W; Krifka S
    Biomaterials; 2014 Mar; 35(9):2890-904. PubMed ID: 24411679
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Infiltrating mast cells increase prostate cancer chemotherapy and radiotherapy resistances via modulation of p38/p53/p21 and ATM signals.
    Xie H; Li C; Dang Q; Chang LS; Li L
    Oncotarget; 2016 Jan; 7(2):1341-53. PubMed ID: 26625310
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synergistic effects of topoisomerase I inhibitor, SN38, on Fas-mediated apoptosis.
    Cao Y; Jin ZX; Tong XP; Yue S; Sakai T; Kawanami T; Sawaki T; Miki M; Iwao H; Nakajima A; Masaki Y; Fukushima Y; Fujita Y; Nakajima H; Okazaki T; Umehara H
    Anticancer Res; 2010 Oct; 30(10):3911-7. PubMed ID: 21036702
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Imiquimod activates p53-dependent apoptosis in a human basal cell carcinoma cell line.
    Huang SW; Chang SH; Mu SW; Jiang HY; Wang ST; Kao JK; Huang JL; Wu CY; Chen YJ; Shieh JJ
    J Dermatol Sci; 2016 Mar; 81(3):182-91. PubMed ID: 26775629
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differing effects of breast cancer 1, early onset (BRCA1) and ataxia-telangiectasia mutated (ATM) mutations on cellular responses to ionizing radiation.
    Mamon HJ; Dahlberg W; Azzam EI; Nagasawa H; Muto MG; Little JB
    Int J Radiat Biol; 2003 Oct; 79(10):817-29. PubMed ID: 14630541
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Topoisomerase poisons differentially activate DNA damage checkpoints through ataxia-telangiectasia mutated-dependent and -independent mechanisms.
    Siu WY; Lau A; Arooz T; Chow JP; Ho HT; Poon RY
    Mol Cancer Ther; 2004 May; 3(5):621-32. PubMed ID: 15141020
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 53BP1 loss induces chemoresistance of colorectal cancer cells to 5-fluorouracil by inhibiting the ATM-CHK2-P53 pathway.
    Yao J; Huang A; Zheng X; Liu T; Lin Z; Zhang S; Yang Q; Zhang T; Ma H
    J Cancer Res Clin Oncol; 2017 Mar; 143(3):419-431. PubMed ID: 27838786
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.