BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

364 related articles for article (PubMed ID: 27639964)

  • 1. Insights into an efficient light-driven hybrid P450 BM3 enzyme from crystallographic, spectroscopic and biochemical studies.
    Spradlin J; Lee D; Mahadevan S; Mahomed M; Tang L; Lam Q; Colbert A; Shafaat OS; Goodin D; Kloos M; Kato M; Cheruzel LE
    Biochim Biophys Acta; 2016 Dec; 1864(12):1732-1738. PubMed ID: 27639964
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A series of hybrid P450 BM3 enzymes with different catalytic activity in the light-initiated hydroxylation of lauric acid.
    Tran NH; Huynh N; Chavez G; Nguyen A; Dwaraknath S; Nguyen TA; Nguyen M; Cheruzel L
    J Inorg Biochem; 2012 Oct; 115():50-6. PubMed ID: 22922311
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Electron transfer in flavocytochrome P450 BM3: kinetics of flavin reduction and oxidation, the role of cysteine 999, and relationships with mammalian cytochrome P450 reductase.
    Roitel O; Scrutton NS; Munro AW
    Biochemistry; 2003 Sep; 42(36):10809-21. PubMed ID: 12962506
    [TBL] [Abstract][Full Text] [Related]  

  • 4. An efficient light-driven P450 BM3 biocatalyst.
    Tran NH; Nguyen D; Dwaraknath S; Mahadevan S; Chavez G; Nguyen A; Dao T; Mullen S; Nguyen TA; Cheruzel LE
    J Am Chem Soc; 2013 Oct; 135(39):14484-7. PubMed ID: 24040992
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Glutamate-haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3.
    Girvan HM; Levy CW; Williams P; Fisher K; Cheesman MR; Rigby SE; Leys D; Munro AW
    Biochem J; 2010 Apr; 427(3):455-66. PubMed ID: 20180779
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Correlating the para-Substituent Effects on Ru(II)-Polypyridine Photophysical Properties and on the Corresponding Hybrid P450 BM3 Enzymes Photocatalytic Activity.
    Shalan H; Colbert A; Nguyen TT; Kato M; Cheruzel L
    Inorg Chem; 2017 Jun; 56(11):6558-6564. PubMed ID: 28537742
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Oxygen activation and electron transfer in flavocytochrome P450 BM3.
    Ost TW; Clark J; Mowat CG; Miles CS; Walkinshaw MD; Reid GA; Chapman SK; Daff S
    J Am Chem Soc; 2003 Dec; 125(49):15010-20. PubMed ID: 14653735
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Crystallographic insights into a cobalt (III) sepulchrate based alternative cofactor system of P450 BM3 monooxygenase.
    Panneerselvam S; Shehzad A; Mueller-Dieckmann J; Wilmanns M; Bocola M; Davari MD; Schwaneberg U
    Biochim Biophys Acta Proteins Proteom; 2018 Jan; 1866(1):134-140. PubMed ID: 28739446
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effect of Mutation and Substrate Binding on the Stability of Cytochrome P450BM3 Variants.
    Geronimo I; Denning CA; Rogers WE; Othman T; Huxford T; Heidary DK; Glazer EC; Payne CM
    Biochemistry; 2016 Jun; 55(25):3594-606. PubMed ID: 27267136
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel haem co-ordination variants of flavocytochrome P450BM3.
    Girvan HM; Toogood HS; Littleford RE; Seward HE; Smith WE; Ekanem IS; Leys D; Cheesman MR; Munro AW
    Biochem J; 2009 Jan; 417(1):65-76. PubMed ID: 18721129
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Insights into electron leakage in the reaction cycle of cytochrome P450 BM3 revealed by kinetic modeling and mutagenesis.
    Lim JB; Barker KA; Eller KA; Jiang L; Molina V; Saifee JF; Sikes HD
    Protein Sci; 2015 Nov; 24(11):1874-83. PubMed ID: 26311413
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural analysis of Cytochrome P450 BM3 mutant M11 in complex with dithiothreitol.
    Frydenvang K; Verkade-Vreeker MCA; Dohmen F; Commandeur JNM; Rafiq M; Mirza O; Jørgensen FS; Geerke DP
    PLoS One; 2019; 14(5):e0217292. PubMed ID: 31125381
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A highly active single-mutation variant of P450BM3 (CYP102A1).
    Whitehouse CJ; Bell SG; Yang W; Yorke JA; Blanford CF; Strong AJ; Morse EJ; Bartlam M; Rao Z; Wong LL
    Chembiochem; 2009 Jul; 10(10):1654-6. PubMed ID: 19492389
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The full-length cytochrome P450 enzyme CYP102A1 dimerizes at its reductase domains and has flexible heme domains for efficient catalysis.
    Zhang H; Yokom AL; Cheng S; Su M; Hollenberg PF; Southworth DR; Osawa Y
    J Biol Chem; 2018 May; 293(20):7727-7736. PubMed ID: 29618513
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural and spectroscopic characterization of P450 BM3 mutants with unprecedented P450 heme iron ligand sets. New heme ligation states influence conformational equilibria in P450 BM3.
    Girvan HM; Seward HE; Toogood HS; Cheesman MR; Leys D; Munro AW
    J Biol Chem; 2007 Jan; 282(1):564-72. PubMed ID: 17077084
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phenylalanine 393 exerts thermodynamic control over the heme of flavocytochrome P450 BM3.
    Ost TW; Miles CS; Munro AW; Murdoch J; Reid GA; Chapman SK
    Biochemistry; 2001 Nov; 40(45):13421-9. PubMed ID: 11695888
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Engineering bacterial cytochrome P450 (P450) BM3 into a prototype with human P450 enzyme activity using indigo formation.
    Park SH; Kim DH; Kim D; Kim DH; Jung HC; Pan JG; Ahn T; Kim D; Yun CH
    Drug Metab Dispos; 2010 May; 38(5):732-9. PubMed ID: 20100815
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure, electronic properties and catalytic behaviour of an activity-enhancing CYP102A1 (P450(BM3)) variant.
    Whitehouse CJ; Yang W; Yorke JA; Tufton HG; Ogilvie LC; Bell SG; Zhou W; Bartlam M; Rao Z; Wong LL
    Dalton Trans; 2011 Oct; 40(40):10383-96. PubMed ID: 21603690
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Photooxidation of cytochrome P450-BM3.
    Ener ME; Lee YT; Winkler JR; Gray HB; Cheruzel L
    Proc Natl Acad Sci U S A; 2010 Nov; 107(44):18783-6. PubMed ID: 20947800
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Improving the activity of cytochrome P450 BM-3 catalyzing indole hydroxylation by directed evolution.
    Pengpai Z; Sheng H; Lehe M; Yinlin L; Zhihua J; Guixiang H
    Appl Biochem Biotechnol; 2013 Sep; 171(1):93-103. PubMed ID: 23817788
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.