975 related articles for article (PubMed ID: 27642729)
1. PI3Kγ is a molecular switch that controls immune suppression.
Kaneda MM; Messer KS; Ralainirina N; Li H; Leem CJ; Gorjestani S; Woo G; Nguyen AV; Figueiredo CC; Foubert P; Schmid MC; Pink M; Winkler DG; Rausch M; Palombella VJ; Kutok J; McGovern K; Frazer KA; Wu X; Karin M; Sasik R; Cohen EE; Varner JA
Nature; 2016 Nov; 539(7629):437-442. PubMed ID: 27642729
[TBL] [Abstract][Full Text] [Related]
2. Macrophage Syk-PI3Kγ Inhibits Antitumor Immunity: SRX3207, a Novel Dual Syk-PI3K Inhibitory Chemotype Relieves Tumor Immunosuppression.
Joshi S; Liu KX; Zulcic M; Singh AR; Skola D; Glass CK; Sanders PD; Sharabi AB; Pham TV; Tamayo P; Shiang D; Dinh HQ; Hedrick CC; Morales GA; Garlich JR; Durden DL
Mol Cancer Ther; 2020 Mar; 19(3):755-764. PubMed ID: 31974273
[TBL] [Abstract][Full Text] [Related]
3. PI3Kγ Activates Integrin α
Foubert P; Kaneda MM; Varner JA
Cancer Immunol Res; 2017 Nov; 5(11):957-968. PubMed ID: 28963139
[TBL] [Abstract][Full Text] [Related]
4. Macrophage PI3Kγ Drives Pancreatic Ductal Adenocarcinoma Progression.
Kaneda MM; Cappello P; Nguyen AV; Ralainirina N; Hardamon CR; Foubert P; Schmid MC; Sun P; Mose E; Bouvet M; Lowy AM; Valasek MA; Sasik R; Novelli F; Hirsch E; Varner JA
Cancer Discov; 2016 Aug; 6(8):870-85. PubMed ID: 27179037
[TBL] [Abstract][Full Text] [Related]
5. Anti-inflammation effects of naloxone involve phosphoinositide 3-kinase delta and gamma.
Wang TY; Su NY; Shih PC; Tsai PS; Huang CJ
J Surg Res; 2014 Dec; 192(2):599-606. PubMed ID: 25016442
[TBL] [Abstract][Full Text] [Related]
6. Inhibition of Phosphatidylinositol 3-Kinase γ by IPI-549 Attenuates Abdominal Aortic Aneurysm Formation in Mice.
Liu R; Huang J; Ge Y; Liu S; Huang T; Cai H; Pan B; Zhang Q; Yang P; Liao M; Xu B; Wang W
Eur J Vasc Endovasc Surg; 2020 Aug; 60(2):254-263. PubMed ID: 32423743
[TBL] [Abstract][Full Text] [Related]
7. PI3Kγδ inhibitor plus radiation enhances the antitumour immune effect of PD-1 blockade in syngenic murine breast cancer and humanised patient-derived xenograft model.
Han MG; Jang BS; Kang MH; Na D; Kim IA
Eur J Cancer; 2021 Nov; 157():450-463. PubMed ID: 34601286
[TBL] [Abstract][Full Text] [Related]
8. p84 forms a negative regulatory complex with p110γ to control PI3Kγ signalling during cell migration.
Turvey ME; Klingler-Hoffmann M; Hoffmann P; McColl SR
Immunol Cell Biol; 2015 Sep; 93(8):735-43. PubMed ID: 25753393
[TBL] [Abstract][Full Text] [Related]
9. Stimulation of peripheral kappa opioid receptors inhibits inflammatory hyperalgesia via activation of the PI3Kγ/AKT/nNOS/NO signaling pathway.
Cunha TM; Souza GR; Domingues AC; Carreira EU; Lotufo CM; Funez MI; Verri WA; Cunha FQ; Ferreira SH
Mol Pain; 2012 Feb; 8():10. PubMed ID: 22316281
[TBL] [Abstract][Full Text] [Related]
10. Akt, mTOR and NF-κB pathway activation in Treponema pallidum stimulates M1 macrophages.
Lin LR; Gao ZX; Lin Y; Zhu XZ; Liu W; Liu D; Gao K; Tong ML; Zhang HL; Liu LL; Xiao Y; Niu JJ; Liu F; Yang TC
Int Immunopharmacol; 2018 Jun; 59():181-186. PubMed ID: 29656208
[TBL] [Abstract][Full Text] [Related]
11. Macrophage Activation Status Rather than Repolarization Is Associated with Enhanced Checkpoint Activity in Combination with PI3Kγ Inhibition.
Carnevalli LS; Taylor MA; King M; Coenen-Stass AML; Hughes AM; Bell S; Proia TA; Wang Y; Ramos-Montoya A; Wali N; Carroll D; Singh M; Moschetta M; Gutierrez PM; Gardelli C; Critchlow SE; Klinowska T; Fawell SE; Barry ST
Mol Cancer Ther; 2021 Jun; 20(6):1080-1091. PubMed ID: 33785652
[TBL] [Abstract][Full Text] [Related]
12. PI3Kγ kinase activity is required for optimal T-cell activation and differentiation.
Ladygina N; Gottipati S; Ngo K; Castro G; Ma JY; Banie H; Rao TS; Fung-Leung WP
Eur J Immunol; 2013 Dec; 43(12):3183-96. PubMed ID: 24030559
[TBL] [Abstract][Full Text] [Related]
13. Phosphatidyl Inositol 3 Kinase-Gamma Balances Antiviral and Inflammatory Responses During Influenza A H1N1 Infection: From Murine Model to Genetic Association in Patients.
Garcia CC; Tavares LP; Dias ACF; Kehdy F; Alvarado-Arnez LE; Queiroz-Junior CM; Galvão I; Lima BH; Matos AR; Gonçalves APF; Soriani FM; Moraes MO; Marques JT; Siqueira MM; Machado AMV; Sousa LP; Russo RC; Teixeira MM
Front Immunol; 2018; 9():975. PubMed ID: 29867955
[TBL] [Abstract][Full Text] [Related]
14. PI3Kγ/AKT Signaling in High Molecular Weight Hyaluronan (HMWH)-Induced Anti-Hyperalgesia and Reversal of Nociceptor Sensitization.
Bonet IJM; Khomula EV; Araldi D; Green PG; Levine JD
J Neurosci; 2021 Oct; 41(40):8414-8426. PubMed ID: 34417329
[TBL] [Abstract][Full Text] [Related]
15. PI3K
Jin JR; Gogvadze E; Xavier AR; Bohnacker T; Voelzmann J; Wymann MP
Front Immunol; 2020; 11():585070. PubMed ID: 33193405
[TBL] [Abstract][Full Text] [Related]
16. TLR Crosstalk Activates LRP1 to Recruit Rab8a and PI3Kγ for Suppression of Inflammatory Responses.
Luo L; Wall AA; Tong SJ; Hung Y; Xiao Z; Tarique AA; Sly PD; Fantino E; Marzolo MP; Stow JL
Cell Rep; 2018 Sep; 24(11):3033-3044. PubMed ID: 30208326
[TBL] [Abstract][Full Text] [Related]
17. PI3Kγ integrates cAMP and Akt signalling of the μ-opioid receptor.
Madishetti S; Schneble N; König C; Hirsch E; Schulz S; Müller JP; Wetzker R
Br J Pharmacol; 2014 Jul; 171(13):3328-37. PubMed ID: 24654606
[TBL] [Abstract][Full Text] [Related]
18. Phosphoinositide-3 kinase gamma regulates caspase-1 activation and leukocyte recruitment in acute murine gout.
Tavares LD; Galvão I; Costa VV; Batista NV; Rossi LCR; Brito CB; Reis AC; Queiroz-Junior CM; Braga AD; Coelho FM; Dias AC; Zamboni DS; Pinho V; Teixeira MM; Amaral FA; Souza DG
J Leukoc Biol; 2019 Sep; 106(3):619-629. PubMed ID: 31392775
[TBL] [Abstract][Full Text] [Related]
19. PI3Kγ inhibition alleviates symptoms and increases axon number in experimental autoimmune encephalomyelitis mice.
Li H; Park D; Abdul-Muneer PM; Xu B; Wang H; Xing B; Wu D; Li S
Neuroscience; 2013 Dec; 253():89-99. PubMed ID: 24012746
[TBL] [Abstract][Full Text] [Related]
20. PI3K Inhibition Reduces Mammary Tumor Growth and Facilitates Antitumor Immunity and Anti-PD1 Responses.
Sai J; Owens P; Novitskiy SV; Hawkins OE; Vilgelm AE; Yang J; Sobolik T; Lavender N; Johnson AC; McClain C; Ayers GD; Kelley MC; Sanders M; Mayer IA; Moses HL; Boothby M; Richmond A
Clin Cancer Res; 2017 Jul; 23(13):3371-3384. PubMed ID: 28003307
[No Abstract] [Full Text] [Related]
[Next] [New Search]
