327 related articles for article (PubMed ID: 27643875)
1. Enhancement of Radiation Response in Breast Cancer Stem Cells by Inhibition of Thioredoxin- and Glutathione-Dependent Metabolism.
Rodman SN; Spence JM; Ronnfeldt TJ; Zhu Y; Solst SR; O'Neill RA; Allen BG; Guan X; Spitz DR; Fath MA
Radiat Res; 2016 Oct; 186(4):385-395. PubMed ID: 27643875
[TBL] [Abstract][Full Text] [Related]
2. Simultaneous inhibition of glutathione- and thioredoxin-dependent metabolism is necessary to potentiate 17AAG-induced cancer cell killing via oxidative stress.
Scarbrough PM; Mapuskar KA; Mattson DM; Gius D; Watson WH; Spitz DR
Free Radic Biol Med; 2012 Jan; 52(2):436-43. PubMed ID: 22100505
[TBL] [Abstract][Full Text] [Related]
3. Susceptibility of human head and neck cancer cells to combined inhibition of glutathione and thioredoxin metabolism.
Sobhakumari A; Love-Homan L; Fletcher EV; Martin SM; Parsons AD; Spitz DR; Knudson CM; Simons AL
PLoS One; 2012; 7(10):e48175. PubMed ID: 23118946
[TBL] [Abstract][Full Text] [Related]
4. Combined inhibition of glycolysis, the pentose cycle, and thioredoxin metabolism selectively increases cytotoxicity and oxidative stress in human breast and prostate cancer.
Li L; Fath MA; Scarbrough PM; Watson WH; Spitz DR
Redox Biol; 2015; 4():127-35. PubMed ID: 25560241
[TBL] [Abstract][Full Text] [Related]
5. Targeting redox homeostasis in rhabdomyosarcoma cells: GSH-depleting agents enhance auranofin-induced cell death.
Habermann KJ; Grünewald L; van Wijk S; Fulda S
Cell Death Dis; 2017 Oct; 8(10):e3067. PubMed ID: 28981107
[TBL] [Abstract][Full Text] [Related]
6. Targeting of the Glutathione, Thioredoxin, and Nrf2 Antioxidant Systems in Head and Neck Cancer.
Roh JL; Jang H; Kim EH; Shin D
Antioxid Redox Signal; 2017 Jul; 27(2):106-114. PubMed ID: 27733046
[TBL] [Abstract][Full Text] [Related]
7. Enhancement of carboplatin-mediated lung cancer cell killing by simultaneous disruption of glutathione and thioredoxin metabolism.
Fath MA; Ahmad IM; Smith CJ; Spence J; Spitz DR
Clin Cancer Res; 2011 Oct; 17(19):6206-17. PubMed ID: 21844013
[TBL] [Abstract][Full Text] [Related]
8. Dual targeting of the thioredoxin and glutathione antioxidant systems in malignant B cells: a novel synergistic therapeutic approach.
Kiebala M; Skalska J; Casulo C; Brookes PS; Peterson DR; Hilchey SP; Dai Y; Grant S; Maggirwar SB; Bernstein SH
Exp Hematol; 2015 Feb; 43(2):89-99. PubMed ID: 25448488
[TBL] [Abstract][Full Text] [Related]
9. Selective targeting of the cysteine proteome by thioredoxin and glutathione redox systems.
Go YM; Roede JR; Walker DI; Duong DM; Seyfried NT; Orr M; Liang Y; Pennell KD; Jones DP
Mol Cell Proteomics; 2013 Nov; 12(11):3285-96. PubMed ID: 23946468
[TBL] [Abstract][Full Text] [Related]
10. Disruption of thioredoxin metabolism enhances the toxicity of transforming growth factor β-activated kinase 1 (TAK1) inhibition in KRAS-mutated colon cancer cells.
Hrabe JE; O'Leary BR; Fath MA; Rodman SN; Button AM; Domann FE; Spitz DR; Mezhir JJ
Redox Biol; 2015 Aug; 5():319-327. PubMed ID: 26114584
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of glutathione synthesis eliminates the adaptive response of ascitic hepatoma 22 cells to nedaplatin that targets thioredoxin reductase.
Wang Y; Lu H; Wang D; Li S; Sun K; Wan X; Taylor EW; Zhang J
Toxicol Appl Pharmacol; 2012 Dec; 265(3):342-50. PubMed ID: 22982619
[TBL] [Abstract][Full Text] [Related]
12. D-penicillamine combined with inhibitors of hydroperoxide metabolism enhances lung and breast cancer cell responses to radiation and carboplatin via H
Sciegienka SJ; Solst SR; Falls KC; Schoenfeld JD; Klinger AR; Ross NL; Rodman SN; Spitz DR; Fath MA
Free Radic Biol Med; 2017 Jul; 108():354-361. PubMed ID: 28389407
[TBL] [Abstract][Full Text] [Related]
13. Dual pharmacological inhibition of glutathione and thioredoxin systems synergizes to kill colorectal carcinoma stem cells.
Tanaka G; Inoue K; Shimizu T; Akimoto K; Kubota K
Cancer Med; 2016 Sep; 5(9):2544-57. PubMed ID: 27485632
[TBL] [Abstract][Full Text] [Related]
14. Auranofin radiosensitizes tumor cells through targeting thioredoxin reductase and resulting overproduction of reactive oxygen species.
Wang H; Bouzakoura S; de Mey S; Jiang H; Law K; Dufait I; Corbet C; Verovski V; Gevaert T; Feron O; Van den Berge D; Storme G; De Ridder M
Oncotarget; 2017 May; 8(22):35728-35742. PubMed ID: 28415723
[TBL] [Abstract][Full Text] [Related]
15. Increase in thiol oxidative stress via glutathione reductase inhibition as a novel approach to enhance cancer sensitivity to X-ray irradiation.
Zhao Y; Seefeldt T; Chen W; Carlson L; Stoebner A; Hanson S; Foll R; Matthees DP; Palakurthi S; Guan X
Free Radic Biol Med; 2009 Jul; 47(2):176-83. PubMed ID: 19397999
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of Thioredoxin/Thioredoxin Reductase Induces Synthetic Lethality in Lung Cancers with Compromised Glutathione Homeostasis.
Yan X; Zhang X; Wang L; Zhang R; Pu X; Wu S; Li L; Tong P; Wang J; Meng QH; Jensen VB; Girard L; Minna JD; Roth JA; Swisher SG; Heymach JV; Fang B
Cancer Res; 2019 Jan; 79(1):125-132. PubMed ID: 30401714
[TBL] [Abstract][Full Text] [Related]
17. Inhibition of reductase systems by 2-AAPA modulates peroxiredoxin oxidation and mitochondrial function in A172 glioblastoma cells.
de Souza LF; Schmitz AE; da Silva LCS; de Oliveira KA; Nedel CB; Tasca CI; de Bem AF; Farina M; Dafre AL
Toxicol In Vitro; 2017 Aug; 42():273-280. PubMed ID: 28461233
[TBL] [Abstract][Full Text] [Related]
18. Glutaminase Inhibitors Induce Thiol-Mediated Oxidative Stress and Radiosensitization in Treatment-Resistant Cervical Cancers.
Rashmi R; Jayachandran K; Zhang J; Menon V; Muhammad N; Zahner M; Ruiz F; Zhang S; Cho K; Wang Y; Huang X; Huang Y; McCormick ML; Rogers BE; Spitz DR; Patti GJ; Schwarz JK
Mol Cancer Ther; 2020 Dec; 19(12):2465-2475. PubMed ID: 33087507
[TBL] [Abstract][Full Text] [Related]
19. The thioredoxin antioxidant system.
Lu J; Holmgren A
Free Radic Biol Med; 2014 Jan; 66():75-87. PubMed ID: 23899494
[TBL] [Abstract][Full Text] [Related]
20. Anti-Cancer Effects of Auranofin in Human Lung Cancer Cells by Increasing Intracellular ROS Levels and Depleting GSH Levels.
Cui XY; Park SH; Park WH
Molecules; 2022 Aug; 27(16):. PubMed ID: 36014444
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
