BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

503 related articles for article (PubMed ID: 27646934)

  • 1. Dynamic landscape of pancreatic carcinogenesis reveals early molecular networks of malignancy.
    Kong B; Bruns P; Behler NA; Chang L; Schlitter AM; Cao J; Gewies A; Ruland J; Fritzsche S; Valkovskaya N; Jian Z; Regel I; Raulefs S; Irmler M; Beckers J; Friess H; Erkan M; Mueller NS; Roth S; Hackert T; Esposito I; Theis FJ; Kleeff J; Michalski CW
    Gut; 2018 Jan; 67(1):146-156. PubMed ID: 27646934
    [TBL] [Abstract][Full Text] [Related]  

  • 2. NFATc1 Links EGFR Signaling to Induction of Sox9 Transcription and Acinar-Ductal Transdifferentiation in the Pancreas.
    Chen NM; Singh G; Koenig A; Liou GY; Storz P; Zhang JS; Regul L; Nagarajan S; Kühnemuth B; Johnsen SA; Hebrok M; Siveke J; Billadeau DD; Ellenrieder V; Hessmann E
    Gastroenterology; 2015 May; 148(5):1024-1034.e9. PubMed ID: 25623042
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ductal obstruction promotes formation of preneoplastic lesions from the pancreatic ductal compartment.
    Cheng T; Zhang Z; Jian Z; Raulefs S; Schlitter AM; Steiger K; Maeritz N; Zhao Y; Shen S; Zou X; Ceyhan GO; Friess H; Kleeff J; Michalski CW; Kong B
    Int J Cancer; 2019 May; 144(10):2529-2538. PubMed ID: 30412288
    [TBL] [Abstract][Full Text] [Related]  

  • 4. miR-802 Suppresses Acinar-to-Ductal Reprogramming During Early Pancreatitis and Pancreatic Carcinogenesis.
    Ge W; Goga A; He Y; Silva PN; Hirt CK; Herrmanns K; Guccini I; Godbersen S; Schwank G; Stoffel M
    Gastroenterology; 2022 Jan; 162(1):269-284. PubMed ID: 34547282
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hes1 Controls Exocrine Cell Plasticity and Restricts Development of Pancreatic Ductal Adenocarcinoma in a Mouse Model.
    Hidalgo-Sastre A; Brodylo RL; Lubeseder-Martellato C; Sipos B; Steiger K; Lee M; von Figura G; Grünwald B; Zhong S; Trajkovic-Arsic M; Neff F; Schmid RM; Siveke JT
    Am J Pathol; 2016 Nov; 186(11):2934-2944. PubMed ID: 27639167
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Nicotine promotes initiation and progression of KRAS-induced pancreatic cancer via Gata6-dependent dedifferentiation of acinar cells in mice.
    Hermann PC; Sancho P; Cañamero M; Martinelli P; Madriles F; Michl P; Gress T; de Pascual R; Gandia L; Guerra C; Barbacid M; Wagner M; Vieira CR; Aicher A; Real FX; Sainz B; Heeschen C
    Gastroenterology; 2014 Nov; 147(5):1119-33.e4. PubMed ID: 25127677
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Oncogenic KRAS Reduces Expression of FGF21 in Acinar Cells to Promote Pancreatic Tumorigenesis in Mice on a High-Fat Diet.
    Luo Y; Yang Y; Liu M; Wang D; Wang F; Bi Y; Ji J; Li S; Liu Y; Chen R; Huang H; Wang X; Swidnicka-Siergiejko AK; Janowitz T; Beyaz S; Wang G; Xu S; Bialkowska AB; Luo CK; Pin CL; Liang G; Lu X; Wu M; Shroyer KR; Wolff RA; Plunkett W; Ji B; Li Z; Li E; Li X; Yang VW; Logsdon CD; Abbruzzese JL; Lu W
    Gastroenterology; 2019 Nov; 157(5):1413-1428.e11. PubMed ID: 31352001
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The acinar regulator Gata6 suppresses KrasG12V-driven pancreatic tumorigenesis in mice.
    Martinelli P; Madriles F; Cañamero M; Pau EC; Pozo ND; Guerra C; Real FX
    Gut; 2016 Mar; 65(3):476-86. PubMed ID: 25596178
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hes1 plays an essential role in Kras-driven pancreatic tumorigenesis.
    Nishikawa Y; Kodama Y; Shiokawa M; Matsumori T; Marui S; Kuriyama K; Kuwada T; Sogabe Y; Kakiuchi N; Tomono T; Mima A; Morita T; Ueda T; Tsuda M; Yamauchi Y; Sakuma Y; Ota Y; Maruno T; Uza N; Uesugi M; Kageyama R; Chiba T; Seno H
    Oncogene; 2019 May; 38(22):4283-4296. PubMed ID: 30705405
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Context-Dependent Epigenetic Regulation of Nuclear Factor of Activated T Cells 1 in Pancreatic Plasticity.
    Chen NM; Neesse A; Dyck ML; Steuber B; Koenig AO; Lubeseder-Martellato C; Winter T; Forster T; Bohnenberger H; Kitz J; Reuter-Jessen K; Griesmann H; Gaedcke J; Grade M; Zhang JS; Tsai WC; Siveke J; Schildhaus HU; Ströbel P; Johnsen SA; Ellenrieder V; Hessmann E
    Gastroenterology; 2017 May; 152(6):1507-1520.e15. PubMed ID: 28188746
    [TBL] [Abstract][Full Text] [Related]  

  • 11. mTORC1 and mTORC2 Converge on the Arp2/3 Complex to Promote Kras
    Zhao Y; Schoeps B; Yao D; Zhang Z; Schuck K; Tissen V; Jäger C; Schlitter AM; van der Kammen R; Ludwig C; D'Haese JG; Raulefs S; Maeritz N; Shen S; Zou X; Krüger A; Kleeff J; Michalski CW; Friess H; Innocenti M; Kong B
    Gastroenterology; 2021 Apr; 160(5):1755-1770.e17. PubMed ID: 33388318
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Induction of Pancreatic Inflammation Accelerates Pancreatic Tumorigenesis in Mice.
    Zhuang L; Zhan X; Bi Y; Ji B
    Methods Mol Biol; 2019; 1882():287-297. PubMed ID: 30378063
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ARID1A, a SWI/SNF subunit, is critical to acinar cell homeostasis and regeneration and is a barrier to transformation and epithelial-mesenchymal transition in the pancreas.
    Wang W; Friedland SC; Guo B; O'Dell MR; Alexander WB; Whitney-Miller CL; Agostini-Vulaj D; Huber AR; Myers JR; Ashton JM; Dunne RF; Steiner LA; Hezel AF
    Gut; 2019 Jul; 68(7):1245-1258. PubMed ID: 30228219
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Desmoplasia and oncogene driven acinar-to-ductal metaplasia are concurrent events during acinar cell-derived pancreatic cancer initiation in young adult mice.
    Johnson BL; d'Alincourt Salazar M; Mackenzie-Dyck S; D'Apuzzo M; Shih HP; Manuel ER; Diamond DJ
    PLoS One; 2019; 14(9):e0221810. PubMed ID: 31490946
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Maintenance of acinar cell organization is critical to preventing Kras-induced acinar-ductal metaplasia.
    Shi G; DiRenzo D; Qu C; Barney D; Miley D; Konieczny SF
    Oncogene; 2013 Apr; 32(15):1950-8. PubMed ID: 22665051
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Lunatic Fringe is a potent tumor suppressor in Kras-initiated pancreatic cancer.
    Zhang S; Chung WC; Xu K
    Oncogene; 2016 May; 35(19):2485-95. PubMed ID: 26279302
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Glycogen synthase kinase-3β ablation limits pancreatitis-induced acinar-to-ductal metaplasia.
    Ding L; Liou GY; Schmitt DM; Storz P; Zhang JS; Billadeau DD
    J Pathol; 2017 Sep; 243(1):65-77. PubMed ID: 28639695
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Beta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice.
    Morris JP; Cano DA; Sekine S; Wang SC; Hebrok M
    J Clin Invest; 2010 Feb; 120(2):508-20. PubMed ID: 20071774
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Loss of Activin Receptor Type 1B Accelerates Development of Intraductal Papillary Mucinous Neoplasms in Mice With Activated KRAS.
    Qiu W; Tang SM; Lee S; Turk AT; Sireci AN; Qiu A; Rose C; Xie C; Kitajewski J; Wen HJ; Crawford HC; Sims PA; Hruban RH; Remotti HE; Su GH
    Gastroenterology; 2016 Jan; 150(1):218-228.e12. PubMed ID: 26408346
    [TBL] [Abstract][Full Text] [Related]  

  • 20. KRAS mutation and epithelial-macrophage interplay in pancreatic neoplastic transformation.
    Bishehsari F; Zhang L; Barlass U; Preite NZ; Turturro S; Najor MS; Shetuni BB; Zayas JP; Mahdavinia M; Abukhdeir AM; Keshavarzian A
    Int J Cancer; 2018 Oct; 143(8):1994-2007. PubMed ID: 29756386
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.