BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 27647367)

  • 1. A new Suzuki synthesis of triphenylethylenes that inhibit aromatase and bind to estrogen receptors α and β.
    Zhao LM; Jin HS; Liu J; Skaar TC; Ipe J; Lv W; Flockhart DA; Cushman M
    Bioorg Med Chem; 2016 Nov; 24(21):5400-5409. PubMed ID: 27647367
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis of Triphenylethylene Bisphenols as Aromatase Inhibitors That Also Modulate Estrogen Receptors.
    Lv W; Liu J; Skaar TC; O'Neill E; Yu G; Flockhart DA; Cushman M
    J Med Chem; 2016 Jan; 59(1):157-70. PubMed ID: 26704594
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis of mixed (E,Z)-, (E)-, and (Z)-norendoxifen with dual aromatase inhibitory and estrogen receptor modulatory activities.
    Lv W; Liu J; Lu D; Flockhart DA; Cushman M
    J Med Chem; 2013 Jun; 56(11):4611-8. PubMed ID: 23731360
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design and synthesis of norendoxifen analogues with dual aromatase inhibitory and estrogen receptor modulatory activities.
    Lv W; Liu J; Skaar TC; Flockhart DA; Cushman M
    J Med Chem; 2015 Mar; 58(6):2623-48. PubMed ID: 25751283
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery of a multi-target compound for estrogen receptor-positive (ER
    Almeida CF; Teixeira N; Oliveira A; Augusto TV; Correia-da-Silva G; Ramos MJ; Fernandes PA; Amaral C
    Biochimie; 2021 Feb; 181():65-76. PubMed ID: 33278557
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis of α-methylstilbenes using an aqueous Wittig methodology and application toward the development of potent human aromatase inhibitors.
    Nielsen AJ; Raez-Villanueva S; Crankshaw DJ; Holloway AC; McNulty J
    Bioorg Med Chem Lett; 2019 Jun; 29(11):1395-1398. PubMed ID: 30952594
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Optimization of the aromatase inhibitory activities of pyridylthiazole analogues of resveratrol.
    Mayhoub AS; Marler L; Kondratyuk TP; Park EJ; Pezzuto JM; Cushman M
    Bioorg Med Chem; 2012 Apr; 20(7):2427-34. PubMed ID: 22386564
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Potent aromatase inhibitors and molecular mechanism of inhibitory action.
    Kang H; Xiao X; Huang C; Yuan Y; Tang D; Dai X; Zeng X
    Eur J Med Chem; 2018 Jan; 143():426-437. PubMed ID: 29202405
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The tamoxifen metabolite norendoxifen is a potent and selective inhibitor of aromatase (CYP19) and a potential lead compound for novel therapeutic agents.
    Lu WJ; Xu C; Pei Z; Mayhoub AS; Cushman M; Flockhart DA
    Breast Cancer Res Treat; 2012 May; 133(1):99-109. PubMed ID: 21814747
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, Synthesis, and Biological Evaluation of New Azole Derivatives as Potent Aromatase Inhibitors with Potential Effects against Breast Cancer.
    Kalalinia F; Jouya M; Komachali AK; Aboutourabzadeh SM; Karimi G; Behravan J; Abnous K; Etemad L; Kamali H; Hadizadeh F
    Anticancer Agents Med Chem; 2018; 18(7):1016-1024. PubMed ID: 29336269
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and biological characterization of 3-(imidazol-1-ylmethyl)piperidine sulfonamides as aromatase inhibitors.
    Di Matteo M; Ammazzalorso A; Andreoli F; Caffa I; De Filippis B; Fantacuzzi M; Giampietro L; Maccallini C; Nencioni A; Parenti MD; Soncini D; Del Rio A; Amoroso R
    Bioorg Med Chem Lett; 2016 Jul; 26(13):3192-3194. PubMed ID: 27161804
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evaluation of synthesized coumarin derivatives on aromatase inhibitory activity.
    Yamaguchi Y; Nishizono N; Kobayashi D; Yoshimura T; Wada K; Oda K
    Bioorg Med Chem Lett; 2017 Jun; 27(12):2645-2649. PubMed ID: 28512028
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design and Pharmacophore Study of Triazole Analogues as Aromatase Inhibitors.
    Banjare L
    Anticancer Agents Med Chem; 2024; 24(4):288-303. PubMed ID: 37921212
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-guided identification of novel dual-targeting estrogen receptor α degraders with aromatase inhibitory activity for the treatment of endocrine-resistant breast cancer.
    Xin L; Min J; Hu H; Li Y; Du C; Xie B; Cheng Y; Deng X; Deng X; Shen K; Huang J; Chen CC; Guo RT; Dong C; Zhou HB
    Eur J Med Chem; 2023 May; 253():115328. PubMed ID: 37037140
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ferrozoles: Ferrocenyl derivatives of letrozole with dual effects as potent aromatase inhibitors and cytostatic agents.
    Diaz de Greñu B; Fernández-Aroca DM; Organero JA; Durá G; Jalón FA; Sánchez-Prieto R; Ruiz-Hidalgo MJ; Rodríguez AM; Santos L; Albasanz JL; Manzano BR
    J Biol Inorg Chem; 2023 Sep; 28(6):531-547. PubMed ID: 37458856
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of Novel ERα and Aromatase Dual-Targeting PROTAC Degraders to Overcome Endocrine-Resistant Breast Cancer.
    Xin L; Wang C; Cheng Y; Wang H; Guo X; Deng X; Deng X; Xie B; Hu H; Min C; Dong C; Zhou HB
    J Med Chem; 2024 Jun; 67(11):8913-8931. PubMed ID: 38809993
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lead optimization of 4-imidazolylflavans: new promising aromatase inhibitors.
    Yahiaoui S; Pouget C; Buxeraud J; Chulia AJ; Fagnère C
    Eur J Med Chem; 2011 Jun; 46(6):2541-5. PubMed ID: 21497425
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Recent Progress in the Discovery of Next Generation Inhibitors of Aromatase from the Structure-Function Perspective.
    Ghosh D; Lo J; Egbuta C
    J Med Chem; 2016 Jun; 59(11):5131-48. PubMed ID: 26689671
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pyridine-substituted thiazolylphenol derivatives: Synthesis, modeling studies, aromatase inhibition, and antiproliferative activity evaluation.
    Ertas M; Sahin Z; Berk B; Yurttas L; Biltekin SN; Demirayak S
    Arch Pharm (Weinheim); 2018 Apr; 351(3-4):e1700272. PubMed ID: 29522642
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Novel SERMs based on 3-aryl-4-aryloxy-2H-chromen-2-one skeleton - A possible way to dual ERα/VEGFR-2 ligands for treatment of breast cancer.
    Luo G; Li X; Zhang G; Wu C; Tang Z; Liu L; You Q; Xiang H
    Eur J Med Chem; 2017 Nov; 140():252-273. PubMed ID: 28942113
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.