151 related articles for article (PubMed ID: 27654490)
1. A comparison of safety and efficacy of cytotoxic versus molecularly targeted drugs in pediatric phase I solid tumor oncology trials.
Dorris K; Liu C; Li D; Hummel TR; Wang X; Perentesis J; Kim MO; Fouladi M
Pediatr Blood Cancer; 2017 Mar; 64(3):. PubMed ID: 27654490
[TBL] [Abstract][Full Text] [Related]
2. A Systematic Review of Pediatric Phase I Trials in Oncology: Toxicity and Outcomes in the Era of Targeted Therapies.
Cohen JW; Akshintala S; Kane E; Gnanapragasam H; Widemann BC; Steinberg SM; Shah NN
Oncologist; 2020 Jun; 25(6):532-540. PubMed ID: 31943534
[TBL] [Abstract][Full Text] [Related]
3. Evaluation of the Safety and Benefit of Phase I Oncology Trials for Patients With Primary CNS Tumors.
Gounder MM; Nayak L; Sahebjam S; Muzikansky A; Sanchez AJ; Desideri S; Ye X; Ivy SP; Nabors LB; Prados M; Grossman S; DeAngelis LM; Wen PY
J Clin Oncol; 2015 Oct; 33(28):3186-92. PubMed ID: 26282642
[TBL] [Abstract][Full Text] [Related]
4. Revisiting Risk and Benefit in Early Oncology Trials in the Era of Precision Medicine: A Systematic Review and Meta-Analysis of Phase I Trials of Targeted Single-Agent Anticancer Therapies.
Mackley MP; Fernandez NR; Fletcher B; Woolcott CG; Fernandez CV
JCO Precis Oncol; 2021 Nov; 5():17-26. PubMed ID: 34994588
[TBL] [Abstract][Full Text] [Related]
5. Towards new methods for the determination of dose limiting toxicities and the assessment of the recommended dose for further studies of molecularly targeted agents--dose-Limiting Toxicity and Toxicity Assessment Recommendation Group for Early Trials of Targeted therapies, an European Organisation for Research and Treatment of Cancer-led study.
Postel-Vinay S; Collette L; Paoletti X; Rizzo E; Massard C; Olmos D; Fowst C; Levy B; Mancini P; Lacombe D; Ivy P; Seymour L; Le Tourneau C; Siu LL; Kaye SB; Verweij J; Soria JC
Eur J Cancer; 2014 Aug; 50(12):2040-9. PubMed ID: 24880774
[TBL] [Abstract][Full Text] [Related]
6. Beyond the dose-limiting toxicity period: Dermatologic adverse events of patients on phase 1 trials of the Cancer Therapeutics Evaluation Program.
Drilon A; Eaton AA; Schindler K; Gounder MM; Spriggs DR; Harris P; Ivy SP; Iasonos A; Lacouture ME; Hyman DM
Cancer; 2016 Apr; 122(8):1228-37. PubMed ID: 26916138
[TBL] [Abstract][Full Text] [Related]
7. Defining the risk of toxicity in phase I oncology trials of novel molecularly targeted agents: a single centre experience.
Molife LR; Alam S; Olmos D; Puglisi M; Shah K; Fehrmann R; Trani L; Tjokrowidjaja A; de Bono JS; Banerji U; Kaye SB
Ann Oncol; 2012 Aug; 23(8):1968-1973. PubMed ID: 22408187
[TBL] [Abstract][Full Text] [Related]
8. Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for advanced cancer (SHIVA): a multicentre, open-label, proof-of-concept, randomised, controlled phase 2 trial.
Le Tourneau C; Delord JP; Gonçalves A; Gavoille C; Dubot C; Isambert N; Campone M; Trédan O; Massiani MA; Mauborgne C; Armanet S; Servant N; Bièche I; Bernard V; Gentien D; Jezequel P; Attignon V; Boyault S; Vincent-Salomon A; Servois V; Sablin MP; Kamal M; Paoletti X;
Lancet Oncol; 2015 Oct; 16(13):1324-34. PubMed ID: 26342236
[TBL] [Abstract][Full Text] [Related]
9. Risk and Benefit for Targeted Therapy Agents in Pediatric Phase II Trials in Oncology: A Systematic Review with a Meta-Analysis.
Strzebonska K; Wasylewski MT; Zaborowska L; Polak M; Slugocka E; Stras J; Blukacz M; Gyawali B; Waligora M
Target Oncol; 2021 Jul; 16(4):415-424. PubMed ID: 34110559
[TBL] [Abstract][Full Text] [Related]
10. Challenges of phase 1 clinical trials evaluating immune checkpoint-targeted antibodies.
Postel-Vinay S; Aspeslagh S; Lanoy E; Robert C; Soria JC; Marabelle A
Ann Oncol; 2016 Feb; 27(2):214-24. PubMed ID: 26578728
[TBL] [Abstract][Full Text] [Related]
11. Pediatric phase I trials in oncology: an analysis of study conduct efficiency.
Lee DP; Skolnik JM; Adamson PC
J Clin Oncol; 2005 Nov; 23(33):8431-41. PubMed ID: 16293874
[TBL] [Abstract][Full Text] [Related]
12. Relationship Between Response and Dose in Published, Contemporary Phase I Oncology Trials.
Hazim A; Mills G; Prasad V; Haslam A; Chen EY
J Natl Compr Canc Netw; 2020 Apr; 18(4):428-433. PubMed ID: 32259790
[TBL] [Abstract][Full Text] [Related]
13. Defining dose-limiting toxicity for phase 1 trials of molecularly targeted agents: results of a DLT-TARGETT international survey.
Paoletti X; Le Tourneau C; Verweij J; Siu LL; Seymour L; Postel-Vinay S; Collette L; Rizzo E; Ivy P; Olmos D; Massard C; Lacombe D; Kaye SB; Soria JC
Eur J Cancer; 2014 Aug; 50(12):2050-6. PubMed ID: 24928189
[TBL] [Abstract][Full Text] [Related]
14. Risk of serious toxicity in 1181 patients treated in phase I clinical trials of predominantly targeted anticancer drugs: the M. D. Anderson Cancer Center experience.
Wheler JJ; Tsimberidou AM; Hong DS; Naing A; Falchook GS; Fu S; Moulder S; Stephen B; Wen S; Kurzrock R
Ann Oncol; 2012 Aug; 23(8):1963-1967. PubMed ID: 22377564
[TBL] [Abstract][Full Text] [Related]
15. Towards using a full spectrum of early clinical trial data: a retrospective analysis to compare potential longitudinal categorical models for molecular targeted therapies in oncology.
Colin P; Micallef S; Delattre M; Mancini P; Parent E
Stat Med; 2015 Sep; 34(22):2999-3016. PubMed ID: 26059319
[TBL] [Abstract][Full Text] [Related]
16. Nature and subjectivity of dose-limiting toxicities in contemporary phase 1 trials: comparison of cytotoxic versus non-cytotoxic drugs.
Penel N; Adenis A; Clisant S; Bonneterre J
Invest New Drugs; 2011 Dec; 29(6):1414-9. PubMed ID: 20617363
[TBL] [Abstract][Full Text] [Related]
17. Influence of companion diagnostics on efficacy and safety of targeted anti-cancer drugs: systematic review and meta-analyses.
Ocana A; Ethier JL; Díez-González L; Corrales-Sánchez V; Srikanthan A; Gascón-Escribano MJ; Templeton AJ; Vera-Badillo F; Seruga B; Niraula S; Pandiella A; Amir E
Oncotarget; 2015 Nov; 6(37):39538-49. PubMed ID: 26446908
[TBL] [Abstract][Full Text] [Related]
18. Dose-finding designs for trials of molecularly targeted agents and immunotherapies.
Chiuzan C; Shtaynberger J; Manji GA; Duong JK; Schwartz GK; Ivanova A; Lee SM
J Biopharm Stat; 2017; 27(3):477-494. PubMed ID: 28166468
[TBL] [Abstract][Full Text] [Related]
19. The performance of model-based versus rule-based phase I clinical trials in oncology : A quantitative comparison of the performance of model-based versus rule-based phase I trials with molecularly targeted anticancer drugs over the last 2 years.
van Brummelen EM; Huitema AD; van Werkhoven E; Beijnen JH; Schellens JH
J Pharmacokinet Pharmacodyn; 2016 Jun; 43(3):235-42. PubMed ID: 26960536
[TBL] [Abstract][Full Text] [Related]
20. Efficacy and safety of anticancer drug combinations: a meta-analysis of randomized trials with a focus on immunotherapeutics and gene-targeted compounds.
Jardim DL; De Melo Gagliato D; Nikanjam M; Barkauskas DA; Kurzrock R
Oncoimmunology; 2020; 9(1):1710052. PubMed ID: 32002305
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
