140 related articles for article (PubMed ID: 27655038)
1. Evaluation of the Interplay between Uptake Transport and CYP3A4 Induction in Micropatterned Cocultured Hepatocytes.
Moore A; Chothe PP; Tsao H; Hariparsad N
Drug Metab Dispos; 2016 Dec; 44(12):1910-1919. PubMed ID: 27655038
[TBL] [Abstract][Full Text] [Related]
2. Application of Micropatterned Cocultured Hepatocytes to Evaluate the Inductive Potential and Degradation Rate of Major Xenobiotic Metabolizing Enzymes.
Dixit V; Moore A; Tsao H; Hariparsad N
Drug Metab Dispos; 2016 Feb; 44(2):250-61. PubMed ID: 26658225
[TBL] [Abstract][Full Text] [Related]
3. Quantitative Prediction of CYP3A4 Induction: Impact of Measured, Free, and Intracellular Perpetrator Concentrations from Human Hepatocyte Induction Studies on Drug-Drug Interaction Predictions.
Sun Y; Chothe PP; Sager JE; Tsao H; Moore A; Laitinen L; Hariparsad N
Drug Metab Dispos; 2017 Jun; 45(6):692-705. PubMed ID: 28336578
[TBL] [Abstract][Full Text] [Related]
4. Evaluation of Erythromycin as a Tool to Assess CYP3A Contribution of Low Clearance Compounds in a Long-Term Hepatocyte Culture.
Chan TS; Scaringella YS; Raymond K; Taub ME
Drug Metab Dispos; 2020 Aug; 48(8):690-697. PubMed ID: 32503882
[TBL] [Abstract][Full Text] [Related]
5. Bridging in vitro and in vivo metabolism and transport of faldaprevir in human using a novel cocultured human hepatocyte system, HepatoPac.
Ramsden D; Tweedie DJ; Chan TS; Taub ME; Li Y
Drug Metab Dispos; 2014 Mar; 42(3):394-406. PubMed ID: 24366904
[TBL] [Abstract][Full Text] [Related]
6. Considerations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidances from Regulatory Agencies: Focus on CYP3A4 mRNA In Vitro Response Thresholds, Variability, and Clinical Relevance.
Kenny JR; Ramsden D; Buckley DB; Dallas S; Fung C; Mohutsky M; Einolf HJ; Chen L; Dekeyser JG; Fitzgerald M; Goosen TC; Siu YA; Walsky RL; Zhang G; Tweedie D; Hariparsad N
Drug Metab Dispos; 2018 Sep; 46(9):1285-1303. PubMed ID: 29959133
[TBL] [Abstract][Full Text] [Related]
7. Evaluation of Normalization Methods To Predict CYP3A4 Induction in Six Fully Characterized Cryopreserved Human Hepatocyte Preparations and HepaRG Cells.
Vermet H; Raoust N; Ngo R; Esserméant L; Klieber S; Fabre G; Boulenc X
Drug Metab Dispos; 2016 Jan; 44(1):50-60. PubMed ID: 26467767
[TBL] [Abstract][Full Text] [Related]
8. Cryopreserved human hepatocytes as alternative in vitro model for cytochrome p450 induction studies.
Garcia M; Rager J; Wang Q; Strab R; Hidalgo IJ; Owen A; Li J
In Vitro Cell Dev Biol Anim; 2003; 39(7):283-7. PubMed ID: 14599235
[TBL] [Abstract][Full Text] [Related]
9. Applying Stable Isotope Labeled Amino Acids in Micropatterned Hepatocyte Coculture to Directly Determine the Degradation Rate Constant for CYP3A4.
Takahashi RH; Shahidi-Latham SK; Wong S; Chang JH
Drug Metab Dispos; 2017 Jun; 45(6):581-585. PubMed ID: 28289057
[TBL] [Abstract][Full Text] [Related]
10. Selective Suppression of CYP3A4 mRNA and Enzyme Activity by Epidermal Growth Factor in Plated Human Hepatocytes.
Zhang JG; Wang D; Ho T; Clark RJ; Stresser DM
Drug Metab Lett; 2017; 11(2):119-127. PubMed ID: 29189189
[TBL] [Abstract][Full Text] [Related]
11. Simple Evaluation Method for CYP3A4 Induction from Human Hepatocytes: The Relative Factor Approach with an Induction Detection Limit Concentration Based on the
Kuramoto S; Kato M; Shindoh H; Kaneko A; Ishigai M; Miyauchi S
Drug Metab Dispos; 2017 Nov; 45(11):1139-1145. PubMed ID: 28821485
[TBL] [Abstract][Full Text] [Related]
12. Evaluation of calibration curve-based approaches to predict clinical inducers and noninducers of CYP3A4 with plated human hepatocytes.
Zhang JG; Ho T; Callendrello AL; Clark RJ; Santone EA; Kinsman S; Xiao D; Fox LG; Einolf HJ; Stresser DM
Drug Metab Dispos; 2014 Sep; 42(9):1379-91. PubMed ID: 24924386
[TBL] [Abstract][Full Text] [Related]
13. Predictive utility of in vitro rifampin induction data generated in fresh and cryopreserved human hepatocytes, Fa2N-4, and HepaRG cells.
Templeton IE; Houston JB; Galetin A
Drug Metab Dispos; 2011 Oct; 39(10):1921-9. PubMed ID: 21771933
[TBL] [Abstract][Full Text] [Related]
14. A 96-well plate assay for CYP4503A induction using cryopreserved human hepatocytes.
Kamiguchi N; Aoyama E; Okuda T; Moriwaki T
Drug Metab Dispos; 2010 Nov; 38(11):1912-6. PubMed ID: 20699409
[TBL] [Abstract][Full Text] [Related]
15. Evaluation of 309 molecules as inducers of CYP3A4, CYP2B6, CYP1A2, OATP1B1, OCT1, MDR1, MRP2, MRP3 and BCRP in cryopreserved human hepatocytes in sandwich culture.
Badolo L; Jensen B; Säll C; Norinder U; Kallunki P; Montanari D
Xenobiotica; 2015 Feb; 45(2):177-87. PubMed ID: 25183402
[TBL] [Abstract][Full Text] [Related]
16. Prediction of Drug-Drug Interactions Arising from CYP3A induction Using a Physiologically Based Dynamic Model.
Almond LM; Mukadam S; Gardner I; Okialda K; Wong S; Hatley O; Tay S; Rowland-Yeo K; Jamei M; Rostami-Hodjegan A; Kenny JR
Drug Metab Dispos; 2016 Jun; 44(6):821-32. PubMed ID: 27026679
[TBL] [Abstract][Full Text] [Related]
17. The utility of cold-preserved human hepatocytes in studies on cytochrome P450 induction and hepatic drug transport.
Juric S; Lundquist P; Hu Y; Juréus A; Sohlenius-Sternbeck AK
Xenobiotica; 2013 Sep; 43(9):785-91. PubMed ID: 23570537
[TBL] [Abstract][Full Text] [Related]
18. Physiologically based pharmacokinetic modeling of CYP3A4 induction by rifampicin in human: influence of time between substrate and inducer administration.
Baneyx G; Parrott N; Meille C; Iliadis A; Lavé T
Eur J Pharm Sci; 2014 Jun; 56():1-15. PubMed ID: 24530864
[TBL] [Abstract][Full Text] [Related]
19. Generating an in vitro-in vivo correlation for metabolism and liver enrichment of a hepatitis C virus drug, faldaprevir, using a rat hepatocyte model (HepatoPac).
Ramsden D; Tweedie DJ; St George R; Chen LZ; Li Y
Drug Metab Dispos; 2014 Mar; 42(3):407-14. PubMed ID: 24366905
[TBL] [Abstract][Full Text] [Related]
20. Effect of Gevokizumab on Interleukin-1β-Mediated Cytochrome P450 3A4 and Drug Transporter Repression in Cultured Human Hepatocytes.
Moreau A; Le Vée M; Jouan E; Denizot C; Parmentier Y; Fardel O
Eur J Drug Metab Pharmacokinet; 2017 Oct; 42(5):871-878. PubMed ID: 28260174
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]