87 related articles for article (PubMed ID: 27655071)
1. Leucine-zipper and Sterile-α Motif Kinase (ZAK): A Potential Target for Drug Discovery.
Chang Y; Zhang Q; Li Z; Ding K; Lu X
Curr Med Chem; 2016; 23(33):3801-3812. PubMed ID: 27655071
[TBL] [Abstract][Full Text] [Related]
2. Tissue distribution and functional expression of a cDNA encoding a novel mixed lineage kinase.
Bloem LJ; Pickard TR; Acton S; Donoghue M; Beavis RC; Knierman MD; Wang X
J Mol Cell Cardiol; 2001 Sep; 33(9):1739-50. PubMed ID: 11549352
[TBL] [Abstract][Full Text] [Related]
3. Cloning and expression of ZAK, a mixed lineage kinase-like protein containing a leucine-zipper and a sterile-alpha motif.
Liu TC; Huang CJ; Chu YC; Wei CC; Chou CC; Chou MY; Chou CK; Yang JJ
Biochem Biophys Res Commun; 2000 Aug; 274(3):811-6. PubMed ID: 10924358
[TBL] [Abstract][Full Text] [Related]
4. Identification and characterization of functional domains in a mixed lineage kinase LZK.
Ikeda A; Masaki M; Kozutsumi Y; Oka S; Kawasaki T
FEBS Lett; 2001 Jan; 488(3):190-5. PubMed ID: 11163770
[TBL] [Abstract][Full Text] [Related]
5. Design, Synthesis, and Structure-Activity Relationships of 1,2,3-Triazole Benzenesulfonamides as New Selective Leucine-Zipper and Sterile-α Motif Kinase (ZAK) Inhibitors.
Yang J; Shibu MA; Kong L; Luo J; BadrealamKhan F; Huang Y; Tu ZC; Yun CH; Huang CY; Ding K; Lu X
J Med Chem; 2020 Mar; 63(5):2114-2130. PubMed ID: 31244114
[TBL] [Abstract][Full Text] [Related]
6. Structure Based Design of N-(3-((1H-Pyrazolo[3,4-b]pyridin-5-yl)ethynyl)benzenesulfonamides as Selective Leucine-Zipper and Sterile-α Motif Kinase (ZAK) Inhibitors.
Chang Y; Lu X; Shibu MA; Dai YB; Luo J; Zhang Y; Li Y; Zhao P; Zhang Z; Xu Y; Tu ZC; Zhang QW; Yun CH; Huang CY; Ding K
J Med Chem; 2017 Jul; 60(13):5927-5932. PubMed ID: 28586211
[TBL] [Abstract][Full Text] [Related]
7. The MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosis.
Xu Z; Maroney AC; Dobrzanski P; Kukekov NV; Greene LA
Mol Cell Biol; 2001 Jul; 21(14):4713-24. PubMed ID: 11416147
[TBL] [Abstract][Full Text] [Related]
8. Identification of structural and functional domains in mixed lineage kinase dual leucine zipper-bearing kinase required for complex formation and stress-activated protein kinase activation.
Nihalani D; Merritt S; Holzman LB
J Biol Chem; 2000 Mar; 275(10):7273-9. PubMed ID: 10702297
[TBL] [Abstract][Full Text] [Related]
9. Dual leucine zipper kinase as a therapeutic target for neurodegenerative conditions.
Ferraris D; Yang Z; Welsbie D
Future Med Chem; 2013 Oct; 5(16):1923-34. PubMed ID: 24175744
[TBL] [Abstract][Full Text] [Related]
10. ZAKβ antagonizes and ameliorates the cardiac hypertrophic and apoptotic effects induced by ZAKα.
Fu CY; Kuo WW; Ho TJ; Wen SY; Lin LC; Tseng YS; Hung HC; Viswanadha VP; Yang JJ; Huang CY
Cell Biochem Funct; 2016 Dec; 34(8):606-612. PubMed ID: 27859413
[TBL] [Abstract][Full Text] [Related]
11. JLP: A scaffolding protein that tethers JNK/p38MAPK signaling modules and transcription factors.
Lee CM; Onésime D; Reddy CD; Dhanasekaran N; Reddy EP
Proc Natl Acad Sci U S A; 2002 Oct; 99(22):14189-94. PubMed ID: 12391307
[TBL] [Abstract][Full Text] [Related]
12. Mixed lineage kinase-dependent JNK activation is governed by interactions of scaffold protein JIP with MAPK module components.
Nihalani D; Meyer D; Pajni S; Holzman LB
EMBO J; 2001 Jul; 20(13):3447-58. PubMed ID: 11432832
[TBL] [Abstract][Full Text] [Related]
13. Mixed lineage kinase LZK forms a functional signaling complex with JIP-1, a scaffold protein of the c-Jun NH(2)-terminal kinase pathway.
Ikeda A; Hasegawa K; Masaki M; Moriguchi T; Nishida E; Kozutsumi Y; Oka S; Kawasaki T
J Biochem; 2001 Dec; 130(6):773-81. PubMed ID: 11726277
[TBL] [Abstract][Full Text] [Related]
14. Mixed - Lineage Protein kinases (MLKs) in inflammation, metabolism, and other disease states.
Craige SM; Reif MM; Kant S
Biochim Biophys Acta; 2016 Sep; 1862(9):1581-6. PubMed ID: 27259981
[TBL] [Abstract][Full Text] [Related]
15. Structure of the Human Protein Kinase ZAK in Complex with Vemurafenib.
Mathea S; Abdul Azeez KR; Salah E; Tallant C; Wolfreys F; Konietzny R; Fischer R; Lou HJ; Brennan PE; Schnapp G; Pautsch A; Kessler BM; Turk BE; Knapp S
ACS Chem Biol; 2016 Jun; 11(6):1595-602. PubMed ID: 26999302
[TBL] [Abstract][Full Text] [Related]
16. Multitasking: Dual Leucine Zipper-Bearing Kinases in Neuronal Development and Stress Management.
Jin Y; Zheng B
Annu Rev Cell Dev Biol; 2019 Oct; 35():501-521. PubMed ID: 31590586
[TBL] [Abstract][Full Text] [Related]
17. Apoptosis signal-regulating kinase 1 plays a pivotal role in angiotensin II-induced cardiac hypertrophy and remodeling.
Izumiya Y; Kim S; Izumi Y; Yoshida K; Yoshiyama M; Matsuzawa A; Ichijo H; Iwao H
Circ Res; 2003 Oct; 93(9):874-83. PubMed ID: 14551246
[TBL] [Abstract][Full Text] [Related]
18. Fragile axons forge the path to gene discovery: a MAP kinase pathway regulates axon regeneration.
O'Brien GS; Sagasti A
Sci Signal; 2009 May; 2(69):pe30. PubMed ID: 19417215
[TBL] [Abstract][Full Text] [Related]
19. Mutations associated with retinopathies alter mitogen-activated protein kinase-induced phosphorylation of neural retina leucine-zipper.
Swain P; Kumar S; Patel D; Richong S; Oberoi P; Ghosh M; Swaroop A
Mol Vis; 2007 Jul; 13():1114-20. PubMed ID: 17653056
[TBL] [Abstract][Full Text] [Related]
20. Transgenic mice with cardiac-specific over-expression of MLK7 have increased mortality when exposed to chronic beta-adrenergic stimulation.
Christe M; Jin N; Wang X; Gould KE; Iversen PW; Yu X; Lorenz JN; Kadambi V; Zuckerman SH; Bloem LJ
J Mol Cell Cardiol; 2004 Sep; 37(3):705-15. PubMed ID: 15350844
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
