These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

83 related articles for article (PubMed ID: 2765527)

  • 1. Oxidative metabolism of spironolactone: evidence for the involvement of electrophilic thiosteroid species in drug-mediated destruction of rat hepatic cytochrome P450.
    Decker CJ; Rashed MS; Baillie TA; Maltby D; Correia MA
    Biochemistry; 1989 Jun; 28(12):5128-36. PubMed ID: 2765527
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Formation of glutathionyl-spironolactone disulfide by rat liver cytochromes P450 or hog liver flavin-containing monooxygenases: a functional probe of two-electron oxidations of the thiosteroid?
    Decker CJ; Cashman JR; Sugiyama K; Maltby D; Correia MA
    Chem Res Toxicol; 1991; 4(6):669-77. PubMed ID: 1807450
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inactivation of rat hepatic cytochrome P-450 by spironolactone.
    Decker C; Sugiyama K; Underwood M; Correia MA
    Biochem Biophys Res Commun; 1986 May; 136(3):1162-9. PubMed ID: 3487316
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inactivation of rat hepatic cytochrome P-450 isozymes by 3,5-dicarbethoxy- 2,6-dimethyl-4-ethyl-1,4-dihydropyridine.
    Sugiyama K; Yao K; Rettie AE; Correia MA
    Chem Res Toxicol; 1989; 2(6):400-10. PubMed ID: 2519730
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The effect of spironolactone treatment on the cytochrome P450-mediated metabolism of the pyrrolizidine alkaloid senecionine by hepatic microsomes from rats and guinea pigs.
    Chung WG; Buhler DR
    Toxicol Appl Pharmacol; 1994 Aug; 127(2):314-9. PubMed ID: 8048076
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Covalent binding of 14C- and 35S-labeled thiocarbamides in rat hepatic microsomes.
    Decker CJ; Doerge DR
    Biochem Pharmacol; 1992 Feb; 43(4):881-8. PubMed ID: 1371686
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effects of a series of 4-alkyl analogues of 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-trimethylpyridine on the major inducible cytochrome P-450 isozymes of rat liver.
    Riddick DS; Park SS; Gelboin HV; Marks GS
    Mol Pharmacol; 1989 May; 35(5):626-34. PubMed ID: 2725472
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cytochrome P450 2C11: Escherichia coli expression, purification, functional characterization, and mechanism-based inactivation of the enzyme.
    Licad-Coles E; He K; Yin H; Correia MA
    Arch Biochem Biophys; 1997 Feb; 338(1):35-42. PubMed ID: 9015385
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Metabolic activation of 1,2,4-trichlorobenzene and pentachlorobenzene by rat liver microsomes: a major role for quinone metabolites.
    den Besten C; Smink MC; de Vries EJ; van Bladeren PJ
    Toxicol Appl Pharmacol; 1991 Apr; 108(2):223-33. PubMed ID: 2017752
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cytochrome P4503A is the major source of N-vinylprotoporphyrin IX formation after administration of 3-[2-(2,4,6-trimethylphenyl)thioethyl]-4-methylsydnone to untreated and dexamethasone-pretreated rats.
    McNamee JP; Marks GS
    Drug Metab Dispos; 1996 Aug; 24(8):872-8. PubMed ID: 8869822
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effect of phenobarbital and spironolactone treatment on the oxidative metabolism of antipyrine by rat liver microsomes.
    Szakács T; Veres Z; Vereczkey L
    Pol J Pharmacol; 2001; 53(1):11-9. PubMed ID: 11785906
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Oxidation of R(+)- and S(-)-carvedilol by rat liver microsomes. Evidence for stereoselective oxidation and characterization of the cytochrome P450 isozymes involved.
    Fujimaki M
    Drug Metab Dispos; 1994; 22(5):700-8. PubMed ID: 7835220
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Involvement of cytochrome P-450IIIA in metabolism of potassium canrenoate to an epoxide: mechanism of inhibition of the epoxide formation by spironolactone and its sulfur-containing metabolite.
    Cook CS; Hauswald C; Oppermann JA; Schoenhard GL
    J Pharmacol Exp Ther; 1993 Jul; 266(1):1-7. PubMed ID: 8331551
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ochratoxin A-induced tumor formation: is there a role of reactive ochratoxin A metabolites?
    Zepnik H; Pähler A; Schauer U; Dekant W
    Toxicol Sci; 2001 Jan; 59(1):59-67. PubMed ID: 11134544
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of human cytochrome P450 isozymes responsible for the in vitro oxidative metabolism of finasteride.
    Huskey SW; Dean DC; Miller RR; Rasmusson GH; Chiu SH
    Drug Metab Dispos; 1995 Oct; 23(10):1126-35. PubMed ID: 8654202
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effect of 17-alpha-ethynylestradiol on activities of cytochrome P450 2B (P450 2B) enzymes: characterization of inactivation of P450s 2B1 and 2B6 and identification of metabolites.
    Kent UM; Mills DE; Rajnarayanan RV; Alworth WL; Hollenberg PF
    J Pharmacol Exp Ther; 2002 Feb; 300(2):549-58. PubMed ID: 11805216
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Participation of P450-dependent oxidation of isoniazid in isonicotinic acid formation in rat liver.
    Ono Y; Wu X; Noda A; Noda H; Yoshitani T
    Biol Pharm Bull; 1998 Apr; 21(4):421-5. PubMed ID: 9586587
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Comparison of cytochrome P450 inhibition assays for drug discovery using human liver microsomes with LC-MS, rhCYP450 isozymes with fluorescence, and double cocktail with LC-MS.
    Di L; Kerns EH; Li SQ; Carter GT
    Int J Pharm; 2007 Apr; 335(1-2):1-11. PubMed ID: 17137735
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In vitro metabolism of alisol A and its metabolites' identification using high-performance liquid chromatography-mass spectrometry.
    Yu Y; Liu Z; Ju P; Zhang Y; Zhang L; Bi K; Chen X
    J Chromatogr B Analyt Technol Biomed Life Sci; 2013 Dec; 941():31-7. PubMed ID: 24184833
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activation of microsomal glutathione S-transferase and inhibition of cytochrome P450 1A1 activity as a model system for detecting protein alkylation by thiourea-containing compounds in rat liver microsomes.
    Onderwater RC; Commandeur JN; Menge WM; Vermeulen NP
    Chem Res Toxicol; 1999 May; 12(5):396-402. PubMed ID: 10328749
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.