These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

176 related articles for article (PubMed ID: 27658206)

  • 21. Progress in pathogenesis studies of spinocerebellar ataxia type 1.
    Cummings CJ; Orr HT; Zoghbi HY
    Philos Trans R Soc Lond B Biol Sci; 1999 Jun; 354(1386):1079-81. PubMed ID: 10434309
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Increased huntingtin protein length reduces the number of polyglutamine-induced gene expression changes in mouse models of Huntington's disease.
    Chan EY; Luthi-Carter R; Strand A; Solano SM; Hanson SA; DeJohn MM; Kooperberg C; Chase KO; DiFiglia M; Young AB; Leavitt BR; Cha JH; Aronin N; Hayden MR; Olson JM
    Hum Mol Genet; 2002 Aug; 11(17):1939-51. PubMed ID: 12165556
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Striatal Mutant Huntingtin Protein Levels Decline with Age in Homozygous Huntington's Disease Knock-In Mouse Models.
    Franich NR; Basso M; André EA; Ochaba J; Kumar A; Thein S; Fote G; Kachemov M; Lau AL; Yeung SY; Osmand A; Zeitlin SO; Ratan RR; Thompson LM; Steffan JS
    J Huntingtons Dis; 2018; 7(2):137-150. PubMed ID: 29843246
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Secondary structures of native and pathogenic huntingtin N-terminal fragments.
    Długosz M; Trylska J
    J Phys Chem B; 2011 Oct; 115(40):11597-608. PubMed ID: 21910495
    [TBL] [Abstract][Full Text] [Related]  

  • 25. HSP90 recognizes the N-terminus of huntingtin involved in regulation of huntingtin aggregation by USP19.
    He WT; Xue W; Gao YG; Hong JY; Yue HW; Jiang LL; Hu HY
    Sci Rep; 2017 Nov; 7(1):14797. PubMed ID: 29093475
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Cell death triggered by polyglutamine-expanded huntingtin in a neuronal cell line is associated with degradation of CREB-binding protein.
    Jiang H; Nucifora FC; Ross CA; DeFranco DB
    Hum Mol Genet; 2003 Jan; 12(1):1-12. PubMed ID: 12490527
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Intersectin enhances huntingtin aggregation and neurodegeneration through activation of c-Jun-NH2-terminal kinase.
    Scappini E; Koh TW; Martin NP; O'Bryan JP
    Hum Mol Genet; 2007 Aug; 16(15):1862-71. PubMed ID: 17550941
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Pathogenic Huntington Alters BMP Signaling and Synaptic Growth through Local Disruptions of Endosomal Compartments.
    Akbergenova Y; Littleton JT
    J Neurosci; 2017 Mar; 37(12):3425-3439. PubMed ID: 28235896
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The Biology of Huntingtin.
    Saudou F; Humbert S
    Neuron; 2016 Mar; 89(5):910-26. PubMed ID: 26938440
    [TBL] [Abstract][Full Text] [Related]  

  • 30. A structure-based analysis of huntingtin mutant polyglutamine aggregation and toxicity: evidence for a compact beta-sheet structure.
    Poirier MA; Jiang H; Ross CA
    Hum Mol Genet; 2005 Mar; 14(6):765-74. PubMed ID: 15689354
    [TBL] [Abstract][Full Text] [Related]  

  • 31. PolyQ-Expansion Causes Mitochondria Fragmentation Independent of Huntingtin and Is Distinct from Traumatic Brain Injury (TBI)/Mechanical Stress-Mediated Fragmentation Which Results from Cell Death.
    Swinter K; Salah D; Rathnayake R; Gunawardena S
    Cells; 2023 Oct; 12(19):. PubMed ID: 37830620
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Mutational analysis implicates the amyloid fibril as the toxic entity in Huntington's disease.
    Drombosky KW; Rode S; Kodali R; Jacob TC; Palladino MJ; Wetzel R
    Neurobiol Dis; 2018 Dec; 120():126-138. PubMed ID: 30171891
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Effects of intracellular expression of anti-huntingtin antibodies of various specificities on mutant huntingtin aggregation and toxicity.
    Khoshnan A; Ko J; Patterson PH
    Proc Natl Acad Sci U S A; 2002 Jan; 99(2):1002-7. PubMed ID: 11792860
    [TBL] [Abstract][Full Text] [Related]  

  • 34. New anti-huntingtin monoclonal antibodies: implications for huntingtin conformation and its binding proteins.
    Ko J; Ou S; Patterson PH
    Brain Res Bull; 2001 Oct-Nov 1; 56(3-4):319-29. PubMed ID: 11719267
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Precise Excision of the CAG Tract from the Huntingtin Gene by Cas9 Nickases.
    Dabrowska M; Juzwa W; Krzyzosiak WJ; Olejniczak M
    Front Neurosci; 2018; 12():75. PubMed ID: 29535594
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Adenovirus vector-based in vitro neuronal cell model for Huntington's disease with human disease-like differential aggregation and degeneration.
    Dong X; Zong S; Witting A; Lindenberg KS; Kochanek S; Huang B
    J Gene Med; 2012 Jul; 14(7):468-81. PubMed ID: 22700462
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Huntingtin exon 1 deletion does not alter the subcellular distribution of huntingtin and gene transcription in mice.
    Zhao X; Sun Y; Wang Z; Chen L; Li S; Li XJ
    Front Cell Neurosci; 2022; 16():1021592. PubMed ID: 36439204
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Coaggregation of polyglutamine (polyQ) proteins is mediated by polyQ-tract interactions and impairs cellular proteostasis.
    Hong JY; Wang JY; Yue HW; Zhang XL; Zhang SX; Jiang LL; Hu HY
    Acta Biochim Biophys Sin (Shanghai); 2023 May; 55(5):736-748. PubMed ID: 37171184
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Cell-to-cell Transmission of Polyglutamine Aggregates in
    Kim DK; Cho KW; Ahn WJ; Perez-Acuña D; Jeong H; Lee HJ; Lee SJ
    Exp Neurobiol; 2017 Dec; 26(6):321-328. PubMed ID: 29302199
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Scalable production in human cells and biochemical characterization of full-length normal and mutant huntingtin.
    Huang B; Lucas T; Kueppers C; Dong X; Krause M; Bepperling A; Buchner J; Voshol H; Weiss A; Gerrits B; Kochanek S
    PLoS One; 2015; 10(3):e0121055. PubMed ID: 25799558
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.