319 related articles for article (PubMed ID: 27671350)
1. Apelin binding to human APJ receptor leads to biased signaling.
Kumar P; Ashokan A; Aradhyam GK
Biochim Biophys Acta; 2016 Dec; 1864(12):1748-1756. PubMed ID: 27671350
[TBL] [Abstract][Full Text] [Related]
2. Molecular determinants on extracellular loop domains that dictate interaction between β-arrestin and human APJ receptor.
Ashokan A; Kameswaran M; Aradhyam GK
FEBS Lett; 2019 Mar; 593(6):634-643. PubMed ID: 30801688
[TBL] [Abstract][Full Text] [Related]
3. Critical APJ receptor residues in extracellular domains that influence effector selectivity.
Ashokan A; Harisankar HS; Kameswaran M; Aradhyam GK
FEBS J; 2021 Nov; 288(22):6543-6562. PubMed ID: 34076959
[TBL] [Abstract][Full Text] [Related]
4. GPCR structure and function relationship: identification of a biased apelin receptor mutant.
Ban T; Li X; Ma X; Yang H; Song Y; Sun Y; Shen M; Li N; Zhang MY; Ma Y; Zhong W; Zhang M; Hu LA
Biochem J; 2018 Dec; 475(23):3813-3826. PubMed ID: 30409826
[TBL] [Abstract][Full Text] [Related]
5. Individual phosphorylation sites at the C-terminus of the apelin receptor play different roles in signal transduction.
Chen J; Chen X; Li S; Jiang Y; Mao H; Zhang R; Ji B; Yan M; Cai X; Wang C
Redox Biol; 2020 Sep; 36():101629. PubMed ID: 32863206
[TBL] [Abstract][Full Text] [Related]
6. Identification of serine 348 on the apelin receptor as a novel regulatory phosphorylation site in apelin-13-induced G protein-independent biased signaling.
Chen X; Bai B; Tian Y; Du H; Chen J
J Biol Chem; 2014 Nov; 289(45):31173-87. PubMed ID: 25271156
[TBL] [Abstract][Full Text] [Related]
7. Structure-function relationship and physiological role of apelin and its G protein coupled receptor.
Murali S; Aradhyam GK
Biophys Rev; 2023 Feb; 15(1):127-143. PubMed ID: 36919024
[TBL] [Abstract][Full Text] [Related]
8. In Vitro and In Vivo Evaluation of a Small-Molecule APJ (Apelin Receptor) Agonist, BMS-986224, as a Potential Treatment for Heart Failure.
Gargalovic P; Wong P; Onorato J; Finlay H; Wang T; Yan M; Crain E; St-Onge S; Héroux M; Bouvier M; Xu C; Chen XQ; Generaux C; Lawrence M; Wexler R; Gordon D
Circ Heart Fail; 2021 Mar; 14(3):e007351. PubMed ID: 33663236
[TBL] [Abstract][Full Text] [Related]
9. The hypotensive effect of activated apelin receptor is correlated with β-arrestin recruitment.
Besserer-Offroy É; Bérubé P; Côté J; Murza A; Longpré JM; Dumaine R; Lesur O; Auger-Messier M; Leduc R; Marsault É; Sarret P
Pharmacol Res; 2018 May; 131():7-16. PubMed ID: 29530600
[TBL] [Abstract][Full Text] [Related]
10. Structural Basis for Apelin Control of the Human Apelin Receptor.
Ma Y; Yue Y; Ma Y; Zhang Q; Zhou Q; Song Y; Shen Y; Li X; Ma X; Li C; Hanson MA; Han GW; Sickmier EA; Swaminath G; Zhao S; Stevens RC; Hu LA; Zhong W; Zhang M; Xu F
Structure; 2017 Jun; 25(6):858-866.e4. PubMed ID: 28528775
[TBL] [Abstract][Full Text] [Related]
11. Apelin and Elabela/Toddler; double ligands for APJ/Apelin receptor in heart development, physiology, and pathology.
Kuba K; Sato T; Imai Y; Yamaguchi T
Peptides; 2019 Jan; 111():62-70. PubMed ID: 29684595
[TBL] [Abstract][Full Text] [Related]
12. New structural insights into the apelin receptor: identification of key residues for apelin binding.
Gerbier R; Leroux V; Couvineau P; Alvear-Perez R; Maigret B; Llorens-Cortes C; Iturrioz X
FASEB J; 2015 Jan; 29(1):314-22. PubMed ID: 25359495
[TBL] [Abstract][Full Text] [Related]
13. Apelin-36-[L28A] and Apelin-36-[L28C(30kDa-PEG)] peptides that improve diet induced obesity are G protein biased ligands at the apelin receptor.
Nyimanu D; Kuc RE; Williams TL; Bednarek M; Ambery P; Jermutus L; Maguire JJ; Davenport AP
Peptides; 2019 Nov; 121():170139. PubMed ID: 31472173
[TBL] [Abstract][Full Text] [Related]
14. Regulation of rat APJ receptor messenger ribonucleic acid expression in magnocellular neurones of the paraventricular and supraopric nuclei by osmotic stimuli.
O'Carroll AM; Lolait SJ
J Neuroendocrinol; 2003 Jul; 15(7):661-6. PubMed ID: 12787050
[TBL] [Abstract][Full Text] [Related]
15. Expression of apelin and apelin receptor (APJ) in porcine ovarian follicles and in vitro effect of apelin on steroidogenesis and proliferation through APJ activation and different signaling pathways.
Rak A; Drwal E; Rame C; Knapczyk-Stwora K; Słomczyńska M; Dupont J; Gregoraszczuk EL
Theriogenology; 2017 Jul; 96():126-135. PubMed ID: 28532828
[TBL] [Abstract][Full Text] [Related]
16. Gαi-biased apelin analog protects against isoproterenol-induced myocardial dysfunction in rats.
Coquerel D; Delile E; Dumont L; Chagnon F; Murza A; Sainsily X; Salvail D; Sarret P; Marsault E; Auger-Messier M; Lesur O
Am J Physiol Heart Circ Physiol; 2021 Apr; 320(4):H1646-H1656. PubMed ID: 33635165
[TBL] [Abstract][Full Text] [Related]
17. Apela Regulates Fluid Homeostasis by Binding to the APJ Receptor to Activate Gi Signaling.
Deng C; Chen H; Yang N; Feng Y; Hsueh AJ
J Biol Chem; 2015 Jul; 290(30):18261-8. PubMed ID: 25995451
[TBL] [Abstract][Full Text] [Related]
18. Loss of APJ mediated β-arrestin signalling improves high-fat diet induced metabolic dysfunction but does not alter cardiac function in mice.
Li N; Ma X; Ban T; Xu S; Ma Y; Ason B; Hu LA
Biochem J; 2020 Sep; 477(17):3313-3327. PubMed ID: 32779693
[TBL] [Abstract][Full Text] [Related]
19. Biased signaling favoring gi over β-arrestin promoted by an apelin fragment lacking the C-terminal phenylalanine.
Ceraudo E; Galanth C; Carpentier E; Banegas-Font I; Schonegge AM; Alvear-Perez R; Iturrioz X; Bouvier M; Llorens-Cortes C
J Biol Chem; 2014 Aug; 289(35):24599-610. PubMed ID: 25012663
[TBL] [Abstract][Full Text] [Related]
20. Apelin-13 induces ERK1/2 but not p38 MAPK activation through coupling of the human apelin receptor to the Gi2 pathway.
Bai B; Tang J; Liu H; Chen J; Li Y; Song W
Acta Biochim Biophys Sin (Shanghai); 2008 Apr; 40(4):311-8. PubMed ID: 18401529
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]