BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

270 related articles for article (PubMed ID: 27672113)

  • 1. The GATOR1 Complex Regulates Metabolic Homeostasis and the Response to Nutrient Stress in Drosophila melanogaster.
    Wei Y; Reveal B; Cai W; Lilly MA
    G3 (Bethesda); 2016 Dec; 6(12):3859-3867. PubMed ID: 27672113
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The GATOR2 Component Wdr24 Regulates TORC1 Activity and Lysosome Function.
    Cai W; Wei Y; Jarnik M; Reich J; Lilly MA
    PLoS Genet; 2016 May; 12(5):e1006036. PubMed ID: 27166823
    [TBL] [Abstract][Full Text] [Related]  

  • 3. TORC1 regulators Iml1/GATOR1 and GATOR2 control meiotic entry and oocyte development in Drosophila.
    Wei Y; Reveal B; Reich J; Laursen WJ; Senger S; Akbar T; Iida-Jones T; Cai W; Jarnik M; Lilly MA
    Proc Natl Acad Sci U S A; 2014 Dec; 111(52):E5670-7. PubMed ID: 25512509
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The TORC1 inhibitors Nprl2 and Nprl3 mediate an adaptive response to amino-acid starvation in Drosophila.
    Wei Y; Lilly MA
    Cell Death Differ; 2014 Sep; 21(9):1460-8. PubMed ID: 24786828
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Royal jelly attenuates metabolic defects in a
    Cheng Y; Cai J; Fu Y; Feng C; Hao Y; Wei Y
    Biol Open; 2020 Nov; 9(11):. PubMed ID: 33037015
    [TBL] [Abstract][Full Text] [Related]  

  • 6. FKBP39 controls nutrient dependent Nprl3 expression and TORC1 activity in Drosophila.
    Zhou Y; Guo J; Wang X; Cheng Y; Guan J; Barman P; Sun MA; Fu Y; Wei W; Feng C; Lilly MA; Wei Y
    Cell Death Dis; 2021 Jun; 12(6):571. PubMed ID: 34078879
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Wdr59 promotes or inhibits TORC1 activity depending on cellular context.
    Zhang Y; Ting CY; Yang S; Reich J; Fru K; Lilly MA
    Proc Natl Acad Sci U S A; 2023 Jan; 120(1):e2212330120. PubMed ID: 36577058
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The TORC1 inhibitor Nprl2 protects age-related digestive function in
    Xi J; Cai J; Cheng Y; Fu Y; Wei W; Zhang Z; Zhuang Z; Hao Y; Lilly MA; Wei Y
    Aging (Albany NY); 2019 Nov; 11(21):9811-9828. PubMed ID: 31712450
    [TBL] [Abstract][Full Text] [Related]  

  • 9. GATOR1 Mutations Impair PI3 Kinase-Dependent Growth Factor Signaling Regulation of mTORC1.
    Muller M; Bélanger J; Hadj-Aissa I; Zhang C; Sephton CF; Dutchak PA
    Int J Mol Sci; 2024 Feb; 25(4):. PubMed ID: 38396745
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Architecture of the human GATOR1 and GATOR1-Rag GTPases complexes.
    Shen K; Huang RK; Brignole EJ; Condon KJ; Valenstein ML; Chantranupong L; Bomaliyamu A; Choe A; Hong C; Yu Z; Sabatini DM
    Nature; 2018 Apr; 556(7699):64-69. PubMed ID: 29590090
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Drosophila larvae lacking the bcl-2 gene, buffy, are sensitive to nutrient stress, maintain increased basal target of rapamycin (Tor) signaling and exhibit characteristics of altered basal energy metabolism.
    Monserrate JP; Chen MY; Brachmann CB
    BMC Biol; 2012 Jul; 10():63. PubMed ID: 22824239
    [TBL] [Abstract][Full Text] [Related]  

  • 12. REPTOR and REPTOR-BP Regulate Organismal Metabolism and Transcription Downstream of TORC1.
    Tiebe M; Lutz M; De La Garza A; Buechling T; Boutros M; Teleman AA
    Dev Cell; 2015 May; 33(3):272-84. PubMed ID: 25920570
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Involvement of GATOR complex genes in familial focal epilepsies and focal cortical dysplasia.
    Weckhuysen S; Marsan E; Lambrecq V; Marchal C; Morin-Brureau M; An-Gourfinkel I; Baulac M; Fohlen M; Kallay Zetchi C; Seeck M; de la Grange P; Dermaut B; Meurs A; Thomas P; Chassoux F; Leguern E; Picard F; Baulac S
    Epilepsia; 2016 Jun; 57(6):994-1003. PubMed ID: 27173016
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Platelet-derived growth factor/vascular endothelial growth factor receptor inactivation by sunitinib results in Tsc1/Tsc2-dependent inhibition of TORC1.
    Tran TA; Kinch L; Peña-Llopis S; Kockel L; Grishin N; Jiang H; Brugarolas J
    Mol Cell Biol; 2013 Oct; 33(19):3762-79. PubMed ID: 23878397
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The GATOR complex regulates an essential response to meiotic double-stranded breaks in
    Wei Y; Bettedi L; Ting CY; Kim K; Zhang Y; Cai J; Lilly MA
    Elife; 2019 Oct; 8():. PubMed ID: 31650955
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutations in the mammalian target of rapamycin pathway regulators NPRL2 and NPRL3 cause focal epilepsy.
    Ricos MG; Hodgson BL; Pippucci T; Saidin A; Ong YS; Heron SE; Licchetta L; Bisulli F; Bayly MA; Hughes J; Baldassari S; Palombo F; ; Santucci M; Meletti S; Berkovic SF; Rubboli G; Thomas PQ; Scheffer IE; Tinuper P; Geoghegan J; Schreiber AW; Dibbens LM
    Ann Neurol; 2016 Jan; 79(1):120-31. PubMed ID: 26505888
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Regulation of TORC1 by Rag GTPases in nutrient response.
    Kim E; Goraksha-Hicks P; Li L; Neufeld TP; Guan KL
    Nat Cell Biol; 2008 Aug; 10(8):935-45. PubMed ID: 18604198
    [TBL] [Abstract][Full Text] [Related]  

  • 18. DEPDC5 and NPRL3 modulate cell size, filopodial outgrowth, and localization of mTOR in neural progenitor cells and neurons.
    Iffland PH; Baybis M; Barnes AE; Leventer RJ; Lockhart PJ; Crino PB
    Neurobiol Dis; 2018 Jun; 114():184-193. PubMed ID: 29481864
    [TBL] [Abstract][Full Text] [Related]  

  • 19. GATOR1 complex: the common genetic actor in focal epilepsies.
    Baldassari S; Licchetta L; Tinuper P; Bisulli F; Pippucci T
    J Med Genet; 2016 Aug; 53(8):503-10. PubMed ID: 27208208
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Multiplexed suppression of TOR complex 1 induces autophagy during starvation.
    Fukuda T; Shiozaki K
    Autophagy; 2021 Jul; 17(7):1794-1795. PubMed ID: 34085593
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.