These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

84 related articles for article (PubMed ID: 27678118)

  • 1. Genetic analyses of Per.C6 cell clones producing a therapeutic monoclonal antibody regarding productivity and long-term stability.
    Tsuruta LR; Lopes Dos Santos M; Yeda FP; Okamoto OK; Moro AM
    Appl Microbiol Biotechnol; 2016 Dec; 100(23):10031-10041. PubMed ID: 27678118
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A study of monoclonal antibody-producing CHO cell lines: what makes a stable high producer?
    Chusainow J; Yang YS; Yeo JH; Toh PC; Asvadi P; Wong NS; Yap MG
    Biotechnol Bioeng; 2009 Mar; 102(4):1182-96. PubMed ID: 18979540
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Screening and subcloning of high producer transfectomas using semisolid media and automated colony picker.
    Dharshanan S; Hung CS
    Methods Mol Biol; 2014; 1131():105-12. PubMed ID: 24515462
    [TBL] [Abstract][Full Text] [Related]  

  • 4. On the optimal ratio of heavy to light chain genes for efficient recombinant antibody production by CHO cells.
    Schlatter S; Stansfield SH; Dinnis DM; Racher AJ; Birch JR; James DC
    Biotechnol Prog; 2005; 21(1):122-33. PubMed ID: 15903249
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sequential screening by ClonePix FL and intracellular staining facilitate isolation of high producer cell lines for monoclonal antibody manufacturing.
    Roy G; Miro-Quesada G; Zhuang L; Martin T; Zhu J; Wu H; Marelli M; Bowen MA
    J Immunol Methods; 2017 Dec; 451():100-110. PubMed ID: 28890364
    [TBL] [Abstract][Full Text] [Related]  

  • 6. IRES-mediated Tricistronic vectors for enhancing generation of high monoclonal antibody expressing CHO cell lines.
    Ho SC; Bardor M; Feng H; Mariati ; Tong YW; Song Z; Yap MG; Yang Y
    J Biotechnol; 2012 Jan; 157(1):130-9. PubMed ID: 22024589
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Culture temperature modulates aggregation of recombinant antibody in cho cells.
    Gomez N; Subramanian J; Ouyang J; Nguyen MD; Hutchinson M; Sharma VK; Lin AA; Yuk IH
    Biotechnol Bioeng; 2012 Jan; 109(1):125-36. PubMed ID: 21965146
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Generation of stable cell clones expressing mixtures of human antibodies.
    de Kruif J; Kramer A; Nijhuis R; van der Zande V; den Blanken R; Clements C; Visser T; Keehnen R; den Hartog M; Throsby M; Logtenberg T
    Biotechnol Bioeng; 2010 Aug; 106(5):741-50. PubMed ID: 20564612
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Recombinase-mediated cassette exchange (RMCE) for monoclonal antibody expression in the commercially relevant CHOK1SV cell line.
    Zhang L; Inniss MC; Han S; Moffat M; Jones H; Zhang B; Cox WL; Rance JR; Young RJ
    Biotechnol Prog; 2015; 31(6):1645-56. PubMed ID: 26399954
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Biochemical limitations to high-level expression of humanized monoclonal antibodies in transgenic maize seed endosperm.
    Law RD; Russell DA; Thompson LC; Schroeder SC; Middle CM; Tremaine MT; Jury TP; Delannay X; Slater SC
    Biochim Biophys Acta; 2006 Sep; 1760(9):1434-44. PubMed ID: 16842925
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cell line profiling to improve monoclonal antibody production.
    Kang S; Ren D; Xiao G; Daris K; Buck L; Enyenihi AA; Zubarev R; Bondarenko PV; Deshpande R
    Biotechnol Bioeng; 2014 Apr; 111(4):748-60. PubMed ID: 24249214
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Correlation of heavy and light chain mRNA copy numbers to antibody productivity in mouse myeloma production cell lines.
    Dorai H; Csirke B; Scallon B; Ganguly S
    Hybridoma (Larchmt); 2006 Feb; 25(1):1-9. PubMed ID: 16475875
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A clone screening method using mRNA levels to determine specific productivity and product quality for monoclonal antibodies.
    Lee CJ; Seth G; Tsukuda J; Hamilton RW
    Biotechnol Bioeng; 2009 Mar; 102(4):1107-18. PubMed ID: 18985612
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DNA methylation contributes to loss in productivity of monoclonal antibody-producing CHO cell lines.
    Yang Y; Mariati ; Chusainow J; Yap MG
    J Biotechnol; 2010 Jun; 147(3-4):180-5. PubMed ID: 20430058
    [TBL] [Abstract][Full Text] [Related]  

  • 15. High-throughput ClonePix FL analysis of mAb-expressing clones using the UCOE expression system.
    Hou JJ; Hughes BS; Smede M; Leung KM; Levine K; Rigby S; Gray PP; Munro TP
    N Biotechnol; 2014 May; 31(3):214-20. PubMed ID: 24518824
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Evaluation of heavy chain C-terminal deletions on productivity and product quality of monoclonal antibodies in Chinese hamster ovary (CHO) cells.
    Hu Z; Tang D; Misaghi S; Jiang G; Yu C; Yim M; Shaw D; Snedecor B; Laird MW; Shen A
    Biotechnol Prog; 2017 May; 33(3):786-794. PubMed ID: 28188688
    [TBL] [Abstract][Full Text] [Related]  

  • 17. mRNA stability and antibody production in CHO cells: improvement through gene optimization.
    Hung F; Deng L; Ravnikar P; Condon R; Li B; Do L; Saha D; Tsao YS; Merchant A; Liu Z; Shi S
    Biotechnol J; 2010 Apr; 5(4):393-401. PubMed ID: 20222103
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cytogenetic analysis of chimeric antibody-producing CHO cells in the course of dihydrofolate reductase-mediated gene amplification and their stability in the absence of selective pressure.
    Kim SJ; Lee GM
    Biotechnol Bioeng; 1999 Sep; 64(6):741-9. PubMed ID: 10417224
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sodium butyrate stimulates monoclonal antibody over-expression in CHO cells by improving gene accessibility.
    Jiang Z; Sharfstein ST
    Biotechnol Bioeng; 2008 May; 100(1):189-94. PubMed ID: 18023047
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Control of IgG LC:HC ratio in stably transfected CHO cells and study of the impact on expression, aggregation, glycosylation and conformational stability.
    Ho SC; Koh EY; van Beers M; Mueller M; Wan C; Teo G; Song Z; Tong YW; Bardor M; Yang Y
    J Biotechnol; 2013 Jun; 165(3-4):157-66. PubMed ID: 23583871
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.