BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

399 related articles for article (PubMed ID: 27683556)

  • 1. Immunogenomics of Hypermutated Glioblastoma: A Patient with Germline POLE Deficiency Treated with Checkpoint Blockade Immunotherapy.
    Johanns TM; Miller CA; Dorward IG; Tsien C; Chang E; Perry A; Uppaluri R; Ferguson C; Schmidt RE; Dahiya S; Ansstas G; Mardis ER; Dunn GP
    Cancer Discov; 2016 Nov; 6(11):1230-1236. PubMed ID: 27683556
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Successful Treatment of a Patient with Glioblastoma and a Germline POLE Mutation: Where Next?
    Snyder A; Wolchok JD
    Cancer Discov; 2016 Nov; 6(11):1210-1211. PubMed ID: 27807100
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hypermutated tumours in the era of immunotherapy: The paradigm of personalised medicine.
    Nebot-Bral L; Brandao D; Verlingue L; Rouleau E; Caron O; Despras E; El-Dakdouki Y; Champiat S; Aoufouchi S; Leary A; Marabelle A; Malka D; Chaput N; Kannouche PL
    Eur J Cancer; 2017 Oct; 84():290-303. PubMed ID: 28846956
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The somatic POLE P286R mutation defines a unique subclass of colorectal cancer featuring hypermutation, representing a potential genomic biomarker for immunotherapy.
    Ahn SM; Ansari AA; Kim J; Kim D; Chun SM; Kim J; Kim TW; Park I; Yu CS; Jang SJ
    Oncotarget; 2016 Oct; 7(42):68638-68649. PubMed ID: 27612425
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Polymerase proofreading domain mutations: New opportunities for immunotherapy in hypermutated colorectal cancer beyond MMR deficiency.
    Bourdais R; Rousseau B; Pujals A; Boussion H; Joly C; Guillemin A; Baumgaertner I; Neuzillet C; Tournigand C
    Crit Rev Oncol Hematol; 2017 May; 113():242-248. PubMed ID: 28427513
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dramatic response of metastatic cutaneous angiosarcoma to an immune checkpoint inhibitor in a patient with xeroderma pigmentosum: whole-genome sequencing aids treatment decision in end-stage disease.
    Momen S; Fassihi H; Davies HR; Nikolaou C; Degasperi A; Stefanato CM; Dias JML; Dasgupta D; Craythorne E; Sarkany R; Papa S; Nik-Zainal S
    Cold Spring Harb Mol Case Stud; 2019 Oct; 5(5):. PubMed ID: 31645345
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PD-1 Blockade in Solid Tumors with Defects in Polymerase Epsilon.
    Rousseau B; Bieche I; Pasmant E; Hamzaoui N; Leulliot N; Michon L; de Reynies A; Attignon V; Foote MB; Masliah-Planchon J; Svrcek M; Cohen R; Simmet V; Augereau P; Malka D; Hollebecque A; Pouessel D; Gomez-Roca C; Guimbaud R; Bruyas A; Guillet M; Grob JJ; Duluc M; Cousin S; de la Fouchardiere C; Flechon A; Rolland F; Hiret S; Saada-Bouzid E; Bouche O; Andre T; Pannier D; El Hajbi F; Oudard S; Tournigand C; Soria JC; Champiat S; Gerber DG; Stephens D; Lamendola-Essel MF; Maron SB; Diplas BH; Argiles G; Krishnan AR; Tabone-Eglinger S; Ferrari A; Segal NH; Cercek A; Hoog-Labouret N; Legrand F; Simon C; Lamrani-Ghaouti A; Diaz LA; Saintigny P; Chevret S; Marabelle A
    Cancer Discov; 2022 Jun; 12(6):1435-1448. PubMed ID: 35398880
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tumor genotype and immune microenvironment in POLE-ultramutated and MSI-hypermutated Endometrial Cancers: New candidates for checkpoint blockade immunotherapy?
    Gargiulo P; Della Pepa C; Berardi S; Califano D; Scala S; Buonaguro L; Ciliberto G; Brauchli P; Pignata S
    Cancer Treat Rev; 2016 Jul; 48():61-8. PubMed ID: 27362548
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Rare germline variants in POLE and POLD1 encoding the catalytic subunits of DNA polymerases ε and δ in glioma families.
    Weber CAM; Krönke N; Volk V; Auber B; Förster A; Trost D; Geffers R; Esmaeilzadeh M; Lalk M; Nabavi A; Samii A; Krauss JK; Feuerhake F; Hartmann C; Wiese B; Brand F; Weber RG
    Acta Neuropathol Commun; 2023 Nov; 11(1):184. PubMed ID: 37990341
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Immune activation and response to pembrolizumab in POLE-mutant endometrial cancer.
    Mehnert JM; Panda A; Zhong H; Hirshfield K; Damare S; Lane K; Sokol L; Stein MN; Rodriguez-Rodriquez L; Kaufman HL; Ali S; Ross JS; Pavlick DC; Bhanot G; White EP; DiPaola RS; Lovell A; Cheng J; Ganesan S
    J Clin Invest; 2016 Jun; 126(6):2334-40. PubMed ID: 27159395
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Germline RAD54L with somatic POLE defect implicated in Hypermutation phenotype: case report.
    Zohud BA; Wang M; Cai X
    BMC Gastroenterol; 2020 Aug; 20(1):255. PubMed ID: 32758138
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cancers from Novel
    Galati MA; Hodel KP; Gams MS; Sudhaman S; Bridge T; Zahurancik WJ; Ungerleider NA; Park VS; Ercan AB; Joksimovic L; Siddiqui I; Siddaway R; Edwards M; de Borja R; Elshaer D; Chung J; Forster VJ; Nunes NM; Aronson M; Wang X; Ramdas J; Seeley A; Sarosiek T; Dunn GP; Byrd JN; Mordechai O; Durno C; Martin A; Shlien A; Bouffet E; Suo Z; Jackson JG; Hawkins CE; Guidos CJ; Pursell ZF; Tabori U
    Cancer Res; 2020 Dec; 80(24):5606-5618. PubMed ID: 32938641
    [No Abstract]   [Full Text] [Related]  

  • 13. Successful immune checkpoint blockade in a patient with advanced stage microsatellite-unstable biliary tract cancer.
    Czink E; Kloor M; Goeppert B; Fröhling S; Uhrig S; Weber TF; Meinel J; Sutter C; Weiss KH; Schirmacher P; Doeberitz MVK; Jäger D; Springfeld C
    Cold Spring Harb Mol Case Stud; 2017 Sep; 3(5):. PubMed ID: 28619747
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [Not Available].
    Pagès C; Baroudjian B; Lebbé C
    Bull Cancer; 2016 Nov; 103 Suppl 1():S132-S137. PubMed ID: 28057176
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Emerging immunotherapies for malignant glioma: from immunogenomics to cell therapy.
    Dunn GP; Cloughesy TF; Maus MV; Prins RM; Reardon DA; Sonabend AM
    Neuro Oncol; 2020 Oct; 22(10):1425-1438. PubMed ID: 32615600
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Prolonged response of recurrent
    Hwang H; Huang J; Khaddour K; Butt OH; Ansstas G; Chen J; Katumba RG; Kim AH; Leuthardt EC; Campian JL
    CNS Oncol; 2022 Mar; 11(1):CNS81. PubMed ID: 35043686
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Immunomodulation: checkpoint blockade etc.
    Curry WT; Lim M
    Neuro Oncol; 2015 Nov; 17 Suppl 7(Suppl 7):vii26-vii31. PubMed ID: 26516223
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens.
    Gubin MM; Zhang X; Schuster H; Caron E; Ward JP; Noguchi T; Ivanova Y; Hundal J; Arthur CD; Krebber WJ; Mulder GE; Toebes M; Vesely MD; Lam SS; Korman AJ; Allison JP; Freeman GJ; Sharpe AH; Pearce EL; Schumacher TN; Aebersold R; Rammensee HG; Melief CJ; Mardis ER; Gillanders WE; Artyomov MN; Schreiber RD
    Nature; 2014 Nov; 515(7528):577-81. PubMed ID: 25428507
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Emerging immunotherapies for glioblastoma.
    Desai R; Suryadevara CM; Batich KA; Farber SH; Sanchez-Perez L; Sampson JH
    Expert Opin Emerg Drugs; 2016 Jun; 21(2):133-45. PubMed ID: 27223671
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Immune Checkpoint Inhibitors in Gynecological Cancers: Update of Literature and Perspectives of Clinical Research.
    Gadducci A; Guerrieri ME
    Anticancer Res; 2017 Nov; 37(11):5955-5965. PubMed ID: 29061774
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.