These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

110 related articles for article (PubMed ID: 27689727)

  • 1. Synthesis, biological evaluation and molecular modeling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT
    Franchini S; Manasieva LI; Sorbi C; Battisti UM; Fossa P; Cichero E; Denora N; Iacobazzi RM; Cilia A; Pirona L; Ronsisvalle S; Aricò G; Brasili L
    Eur J Med Chem; 2017 Jan; 125():435-452. PubMed ID: 27689727
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure-affinity/activity relationships of 1,4-dioxa-spiro[4.5]decane based ligands at α1 and 5-HT1A receptors.
    Franchini S; Battisti UM; Baraldi A; Prandi A; Fossa P; Cichero E; Tait A; Sorbi C; Marucci G; Cilia A; Pirona L; Brasili L
    Eur J Med Chem; 2014 Nov; 87():248-66. PubMed ID: 25261823
    [TBL] [Abstract][Full Text] [Related]  

  • 3. New serotonin 5-HT1A receptor agonists endowed with antinociceptive activity in vivo.
    Valhondo M; Marco I; Martín-Fontecha M; Vázquez-Villa H; Ramos JA; Berkels R; Lauterbach T; Benhamú B; López-Rodríguez ML
    J Med Chem; 2013 Oct; 56(20):7851-61. PubMed ID: 24050112
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 1,3-Dioxane as a scaffold for potent and selective 5-HT
    Franchini S; Sorbi C; Linciano P; Carnevale G; Tait A; Ronsisvalle S; Buccioni M; Del Bello F; Cilia A; Pirona L; Denora N; Iacobazzi RM; Brasili L
    Eur J Med Chem; 2019 Aug; 176():310-325. PubMed ID: 31112892
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and biological evaluation of 1,3-dioxolane-based 5-HT
    Franchini S; Bencheva LI; Battisti UM; Tait A; Sorbi C; Fossa P; Cichero E; Ronsisvalle S; Aricò G; Denora N; Iacobazzi RM; Cilia A; Pirona L; Brasili L
    Future Med Chem; 2018 Sep; 10(18):2137-2154. PubMed ID: 30043643
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 4-Aryl-1-oxa-4,9-diazaspiro[5.5]undecane Derivatives as Dual μ-Opioid Receptor Agonists and σ
    García M; Virgili M; Alonso M; Alegret C; Fernández B; Port A; Pascual R; Monroy X; Vidal-Torres A; Serafini MT; Vela JM; Almansa C
    J Med Chem; 2020 Mar; 63(5):2434-2454. PubMed ID: 31743642
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Higher-Affinity Agonists of 5-HT1AR Discovered through Tuning the Binding-Site Flexibility.
    Lian P; Li L; Geng C; Zhen X; Fu W
    J Chem Inf Model; 2015 Aug; 55(8):1616-27. PubMed ID: 26131601
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and structure-activity relationship studies in serotonin 5-HT(1A) receptor agonists based on fused pyrrolidone scaffolds.
    Cappelli A; Manini M; Valenti S; Castriconi F; Giuliani G; Anzini M; Brogi S; Butini S; Gemma S; Campiani G; Giorgi G; Mennuni L; Lanza M; Giordani A; Caselli G; Letari O; Makovec F
    Eur J Med Chem; 2013 May; 63():85-94. PubMed ID: 23466604
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and evaluation of arylpiperazines derivatives of 3,5-dioxo-(2H,4H)-1,2,4-triazine as 5-HT1AR ligands.
    Kumar JSD; Majo VJ; Prabhakaran J; Mann JJ
    Bioorg Med Chem Lett; 2014 Oct; 24(19):4759-4762. PubMed ID: 25182564
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of Novel Indolealkylpiperazine Derivatives as Potent 5-HT
    Zhu C; Li X; Peng W; Fu W
    Molecules; 2020 Nov; 25(21):. PubMed ID: 33139658
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 1,3-Dioxolane-based ligands incorporating a lactam or imide moiety: structure-affinity/activity relationship at alpha1-adrenoceptor subtypes and at 5-HT1A receptors.
    Franchini S; Prandi A; Baraldi A; Sorbi C; Tait A; Buccioni M; Marucci G; Cilia A; Pirona L; Fossa P; Cichero E; Brasili L
    Eur J Med Chem; 2010 Sep; 45(9):3740-51. PubMed ID: 20605276
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Antidepressant-like activity and safety profile evaluation of 1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione derivatives as 5-HT1A receptor partial agonists.
    Partyka A; Zagórska A; Kotańska M; Walczak M; Jastrzębska-Więsek M; Knutelska J; Bednarski M; Głuch-Lutwin M; Mordyl B; Janiszewska P; Wesołowska A
    PLoS One; 2020; 15(8):e0237196. PubMed ID: 32764777
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular docking, dynamics simulations and 3D-QSAR modeling of arylpiperazine derivatives of 3,5-dioxo-(2H,4H)-1,2,4-triazine as 5-HT
    Sherin DR; Geethu CK; Prabhakaran J; Mann JJ; Dileep Kumar JS; Manojkumar TK
    Comput Biol Chem; 2019 Feb; 78():108-115. PubMed ID: 30502727
    [TBL] [Abstract][Full Text] [Related]  

  • 14. New serotonin 5-HT(1A) receptor agonists with neuroprotective effect against ischemic cell damage.
    Marco I; Valhondo M; Martín-Fontecha M; Vázquez-Villa H; Del Río J; Planas A; Sagredo O; Ramos JA; Torrecillas IR; Pardo L; Frechilla D; Benhamú B; López-Rodríguez ML
    J Med Chem; 2011 Dec; 54(23):7986-99. PubMed ID: 22029386
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Chemical manipulations on the 1,4-dioxane ring of 5-HT
    Del Bello F; Bonifazi A; Giorgioni G; Quaglia W; Amantini C; Morelli MB; Santoni G; Battiti FO; Vistoli G; Cilia A; Piergentili A
    Eur J Med Chem; 2019 Apr; 168():461-473. PubMed ID: 30844609
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis, biological evaluation, and docking studies of tetrahydrofuran- cyclopentanone- and cyclopentanol-based ligands acting at adrenergic α₁- and serotonine 5-HT1A receptors.
    Prandi A; Franchini S; Manasieva LI; Fossa P; Cichero E; Marucci G; Buccioni M; Cilia A; Pirona L; Brasili L
    J Med Chem; 2012 Jan; 55(1):23-36. PubMed ID: 22145629
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pharmacological, neurochemical, and behavioral profile of JB-788, a new 5-HT1A agonist.
    Picard M; Morisset S; Cloix JF; Bizot JC; Guerin M; Beneteau V; Guillaumet G; Hevor TK
    Neuroscience; 2010 Sep; 169(3):1337-46. PubMed ID: 20580787
    [TBL] [Abstract][Full Text] [Related]  

  • 18. New pyridobenzoxazepine derivatives derived from 5-(4-methylpiperazin-1-yl)-8-chloro-pyrido[2,3-b][1,5]benzoxazepine (JL13): chemical synthesis and pharmacological evaluation.
    Liégeois JF; Deville M; Dilly S; Lamy C; Mangin F; Résimont M; Tarazi FI
    J Med Chem; 2012 Feb; 55(4):1572-82. PubMed ID: 22268448
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis, and pharmacological evaluation of azetedine and pyrrolidine derivatives as dual norepinephrine reuptake inhibitors and 5-HT(1A) partial agonists.
    Pettersson M; Campbell BM; Dounay AB; Gray DL; Xie L; O'Donnell CJ; Stratman NC; Zoski K; Drummond E; Bora G; Probert A; Whisman T
    Bioorg Med Chem Lett; 2011 Jan; 21(2):865-8. PubMed ID: 21185183
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and in vivo evaluation of [(18)F]2-(4-(4-(2-(2-fluoroethoxy)phenyl)piperazin-1-yl)butyl)-4-methyl-1,2,4-triazine-3,5(2H,4H)-dione ([(18)F]FECUMI-101) as an imaging probe for 5-HT1A receptor agonist in nonhuman primates.
    Majo VJ; Milak MS; Prabhakaran J; Mali P; Savenkova L; Simpson NR; Mann JJ; Parsey RV; Kumar JS
    Bioorg Med Chem; 2013 Sep; 21(17):5598-604. PubMed ID: 23816046
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.