BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

129 related articles for article (PubMed ID: 27692832)

  • 1. Synthesis and evaluation of a 2-benzothiazolylphenylmethyl ether class of histamine H4 receptor antagonists.
    Labeeuw O; Levoin N; Billot X; Danvy D; Calmels T; Krief S; Ligneau X; Berrebi-Bertrand I; Robert P; Lecomte JM; Schwartz JC; Capet M
    Bioorg Med Chem Lett; 2016 Nov; 26(21):5263-5266. PubMed ID: 27692832
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification and hit-to-lead exploration of a novel series of histamine H4 receptor inverse agonists.
    Cramp S; Dyke HJ; Higgs C; Clark DE; Gill M; Savy P; Jennings N; Price S; Lockey PM; Norman D; Porres S; Wilson F; Jones A; Ramsden N; Mangano R; Leggate D; Andersson M; Hale R
    Bioorg Med Chem Lett; 2010 Apr; 20(8):2516-9. PubMed ID: 20299215
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Histamine H4 receptor antagonists: the new antihistamines?
    Fung-Leung WP; Thurmond RL; Ling P; Karlsson L
    Curr Opin Investig Drugs; 2004 Nov; 5(11):1174-83. PubMed ID: 15573868
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Clinical Development of Histamine H
    Thurmond RL; Venable J; Savall B; La D; Snook S; Dunford PJ; Edwards JP
    Handb Exp Pharmacol; 2017; 241():301-320. PubMed ID: 28233185
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The first potent and selective non-imidazole human histamine H4 receptor antagonists.
    Jablonowski JA; Grice CA; Chai W; Dvorak CA; Venable JD; Kwok AK; Ly KS; Wei J; Baker SM; Desai PJ; Jiang W; Wilson SJ; Thurmond RL; Karlsson L; Edwards JP; Lovenberg TW; Carruthers NI
    J Med Chem; 2003 Sep; 46(19):3957-60. PubMed ID: 12954048
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Lead identification and optimization of diaminopyrimidines as histamine H4 receptor ligands.
    Sander K; Kottke T; Proschak E; Tanrikulu Y; Schneider EH; Seifert R; Schneider G; Stark H
    Inflamm Res; 2010 Mar; 59 Suppl 2():S249-51. PubMed ID: 20012148
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A new generation of anti-histamines: Histamine H4 receptor antagonists on their way to the clinic.
    Engelhardt H; Smits RA; Leurs R; Haaksma E; de Esch IJ
    Curr Opin Drug Discov Devel; 2009 Sep; 12(5):628-43. PubMed ID: 19736622
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery and SAR of 6-alkyl-2,4-diaminopyrimidines as histamine H₄ receptor antagonists.
    Savall BM; Chavez F; Tays K; Dunford PJ; Cowden JM; Hack MD; Wolin RL; Thurmond RL; Edwards JP
    J Med Chem; 2014 Mar; 57(6):2429-39. PubMed ID: 24495018
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery of a Novel Highly Selective Histamine H4 Receptor Antagonist for the Treatment of Atopic Dermatitis.
    Ko K; Kim HJ; Ho PS; Lee SO; Lee JE; Min CR; Kim YC; Yoon JH; Park EJ; Kwon YJ; Yun JH; Yoon DO; Kim JS; Park WS; Oh SS; Song YM; Cho WK; Morikawa K; Lee KJ; Park CH
    J Med Chem; 2018 Apr; 61(7):2949-2961. PubMed ID: 29579390
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of novel human histamine H4 receptor ligands by large-scale structure-based virtual screening.
    Kiss R; Kiss B; Könczöl A; Szalai F; Jelinek I; László V; Noszál B; Falus A; Keseru GM
    J Med Chem; 2008 Jun; 51(11):3145-53. PubMed ID: 18459760
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of a series of potent and selective human H4 antagonists using ligand efficiency and libraries to explore structure-activity relationship (SAR).
    Masood MA; Selby MD; Bell AS; Mansfield AC; Gardner M; Smith GF; Lane C; Kenyon-Edwards H; Osborne R; Jones RM; Liu WL; Brown CD; Clarke N; Perrucio F; Mowbray CE
    Bioorg Med Chem Lett; 2011 Nov; 21(21):6591-5. PubMed ID: 21955944
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Histamine H4 receptor ligands and their potential therapeutic applications.
    Kiss R; Keseru GM
    Expert Opin Ther Pat; 2009 Feb; 19(2):119-35. PubMed ID: 19441913
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Histamine H3 and H4 receptors as novel drug targets.
    Tiligada E; Zampeli E; Sander K; Stark H
    Expert Opin Investig Drugs; 2009 Oct; 18(10):1519-31. PubMed ID: 19758107
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Azines as histamine H4 receptor antagonists.
    Lazewska D; Kiec-Kononowicz K
    Front Biosci (Schol Ed); 2012 Jan; 4(3):967-87. PubMed ID: 22202103
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Histamine induces proliferation in keratinocytes from patients with atopic dermatitis through the histamine 4 receptor.
    Glatzer F; Gschwandtner M; Ehling S; Rossbach K; Janik K; Klos A; Bäumer W; Kietzmann M; Werfel T; Gutzmer R
    J Allergy Clin Immunol; 2013 Dec; 132(6):1358-67. PubMed ID: 23932072
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tricyclic aminopyrimidine histamine H4 receptor antagonists.
    Savall BM; Gomez L; Chavez F; Curtis M; Meduna SP; Kearney A; Dunford P; Cowden J; Thurmond RL; Grice C; Edwards JP
    Bioorg Med Chem Lett; 2011 Nov; 21(21):6577-81. PubMed ID: 21920744
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The histamine H4 receptor in autoimmune disease.
    Zhang M; Venable JD; Thurmond RL
    Expert Opin Investig Drugs; 2006 Nov; 15(11):1443-52. PubMed ID: 17040202
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A novel series of histamine H4 receptor antagonists based on the pyrido[3,2-d]pyrimidine scaffold: comparison of hERG binding and target residence time with PF-3893787.
    Andaloussi M; Lim HD; van der Meer T; Sijm M; Poulie CB; de Esch IJ; Leurs R; Smits RA
    Bioorg Med Chem Lett; 2013 May; 23(9):2663-70. PubMed ID: 23558237
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Challenges of drug discovery in novel target space. The discovery and evaluation of PF-3893787: a novel histamine H4 receptor antagonist.
    Mowbray CE; Bell AS; Clarke NP; Collins M; Jones RM; Lane CA; Liu WL; Newman SD; Paradowski M; Schenck EJ; Selby MD; Swain NA; Williams DH
    Bioorg Med Chem Lett; 2011 Nov; 21(21):6596-602. PubMed ID: 21920751
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Novel histamine H4 receptor ligands and their potential therapeutic applications: an update.
    Kiss R; Keseru GM
    Expert Opin Ther Pat; 2014 Nov; 24(11):1185-97. PubMed ID: 25219452
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.