BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

503 related articles for article (PubMed ID: 27693422)

  • 1. Endogenously produced nonclassical vitamin D hydroxy-metabolites act as "biased" agonists on VDR and inverse agonists on RORα and RORγ.
    Slominski AT; Kim TK; Hobrath JV; Oak ASW; Tang EKY; Tieu EW; Li W; Tuckey RC; Jetten AM
    J Steroid Biochem Mol Biol; 2017 Oct; 173():42-56. PubMed ID: 27693422
    [TBL] [Abstract][Full Text] [Related]  

  • 2. RORα and ROR γ are expressed in human skin and serve as receptors for endogenously produced noncalcemic 20-hydroxy- and 20,23-dihydroxyvitamin D.
    Slominski AT; Kim TK; Takeda Y; Janjetovic Z; Brozyna AA; Skobowiat C; Wang J; Postlethwaite A; Li W; Tuckey RC; Jetten AM
    FASEB J; 2014 Jul; 28(7):2775-89. PubMed ID: 24668754
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The role of CYP11A1 in the production of vitamin D metabolites and their role in the regulation of epidermal functions.
    Slominski AT; Kim TK; Li W; Yi AK; Postlethwaite A; Tuckey RC
    J Steroid Biochem Mol Biol; 2014 Oct; 144 Pt A():28-39. PubMed ID: 24176765
    [TBL] [Abstract][Full Text] [Related]  

  • 4. CYP11A1‑derived vitamin D hydroxyderivatives as candidates for therapy of basal and squamous cell carcinomas.
    Slominski AT; Brożyna AA; Kim TK; Elsayed MM; Janjetovic Z; Qayyum S; Slominski RM; Oak ASW; Li C; Podgorska E; Li W; Jetten AM; Tuckey RC; Tang EKY; Elmets C; Athar M
    Int J Oncol; 2022 Aug; 61(2):. PubMed ID: 35775377
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Antifibrogenic Activities of CYP11A1-derived Vitamin D3-hydroxyderivatives Are Dependent on RORγ.
    Janjetovic Z; Postlethwaite A; Kang HS; Kim TK; Tuckey RC; Crossman DK; Qayyum S; Jetten AM; Slominski AT
    Endocrinology; 2021 Jan; 162(1):. PubMed ID: 33107570
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Detection of novel CYP11A1-derived secosteroids in the human epidermis and serum and pig adrenal gland.
    Slominski AT; Kim TK; Li W; Postlethwaite A; Tieu EW; Tang EKY; Tuckey RC
    Sci Rep; 2015 Oct; 5():14875. PubMed ID: 26445902
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Chemical synthesis, biological activities and action on nuclear receptors of 20S(OH)D
    Brzeminski P; Fabisiak A; Slominski RM; Kim TK; Janjetovic Z; Podgorska E; Song Y; Saleem M; Reddy SB; Qayyum S; Song Y; Tuckey RC; Atigadda V; Jetten AM; Sicinski RR; Raman C; Slominski AT
    Bioorg Chem; 2022 Apr; 121():105660. PubMed ID: 35168121
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Temporal changes in tissue 1α,25-dihydroxyvitamin D3, vitamin D receptor target genes, and calcium and PTH levels after 1,25(OH)2D3 treatment in mice.
    Chow EC; Quach HP; Vieth R; Pang KS
    Am J Physiol Endocrinol Metab; 2013 May; 304(9):E977-89. PubMed ID: 23482451
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Association among Vitamin D, Retinoic Acid-Related Orphan Receptors, and Vitamin D Hydroxyderivatives in Ovarian Cancer.
    Brożyna AA; Kim TK; Zabłocka M; Jóźwicki W; Yue J; Tuckey RC; Jetten AM; Slominski AT
    Nutrients; 2020 Nov; 12(11):. PubMed ID: 33227893
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Vitamin D receptors (VDR), hydroxylases CYP27B1 and CYP24A1 and retinoid-related orphan receptors (ROR) level in human uveal tract and ocular melanoma with different melanization levels.
    Markiewicz A; Brożyna AA; Podgórska E; Elas M; Urbańska K; Jetten AM; Slominski AT; Jóźwicki W; Orłowska-Heitzman J; Dyduch G; Romanowska-Dixon B
    Sci Rep; 2019 Jun; 9(1):9142. PubMed ID: 31235702
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Evidence that both 1alpha,25-dihydroxyvitamin D3 and 24-hydroxylated D3 enhance human osteoblast differentiation and mineralization.
    van Driel M; Koedam M; Buurman CJ; Roelse M; Weyts F; Chiba H; Uitterlinden AG; Pols HA; van Leeuwen JP
    J Cell Biochem; 2006 Oct; 99(3):922-35. PubMed ID: 16741965
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Vitamin D signaling and melanoma: role of vitamin D and its receptors in melanoma progression and management.
    Slominski AT; Brożyna AA; Zmijewski MA; Jóźwicki W; Jetten AM; Mason RS; Tuckey RC; Elmets CA
    Lab Invest; 2017 Jun; 97(6):706-724. PubMed ID: 28218743
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Production of 22-hydroxy metabolites of vitamin d3 by cytochrome p450scc (CYP11A1) and analysis of their biological activities on skin cells.
    Tuckey RC; Li W; Shehabi HZ; Janjetovic Z; Nguyen MN; Kim TK; Chen J; Howell DE; Benson HA; Sweatman T; Baldisseri DM; Slominski A
    Drug Metab Dispos; 2011 Sep; 39(9):1577-88. PubMed ID: 21677063
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Vitamin D and lumisterol derivatives can act on liver X receptors (LXRs).
    Slominski AT; Kim TK; Qayyum S; Song Y; Janjetovic Z; Oak ASW; Slominski RM; Raman C; Stefan J; Mier-Aguilar CA; Atigadda V; Crossman DK; Golub A; Bilokin Y; Tang EKY; Chen JY; Tuckey RC; Jetten AM; Song Y
    Sci Rep; 2021 Apr; 11(1):8002. PubMed ID: 33850196
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The serum vitamin D metabolome: What we know and what is still to discover.
    Tuckey RC; Cheng CYS; Slominski AT
    J Steroid Biochem Mol Biol; 2019 Feb; 186():4-21. PubMed ID: 30205156
    [TBL] [Abstract][Full Text] [Related]  

  • 16. On the relationship between VDR, RORα and RORγ receptors expression and HIF1-α levels in human melanomas.
    Brożyna AA; Jóźwicki W; Jetten AM; Slominski AT
    Exp Dermatol; 2019 Sep; 28(9):1036-1043. PubMed ID: 31287590
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A second class of nuclear receptors for oxysterols: Regulation of RORalpha and RORgamma activity by 24S-hydroxycholesterol (cerebrosterol).
    Wang Y; Kumar N; Crumbley C; Griffin PR; Burris TP
    Biochim Biophys Acta; 2010 Aug; 1801(8):917-23. PubMed ID: 20211758
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel Vitamin D3 Hydroxymetabolites Require Involvement of the Vitamin D Receptor or Retinoic Acid-Related Orphan Receptors for Their Antifibrogenic Activities in Human Fibroblasts.
    Janjetovic Z; Qayyum S; Reddy SB; Podgorska E; Scott SG; Szpotan J; Mobley AA; Li W; Boda VK; Ravichandran S; Tuckey RC; Jetten AM; Slominski AT
    Cells; 2024 Jan; 13(3):. PubMed ID: 38334631
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Potent antiproliferative effects of 25-hydroxy-16-ene-23-yne-vitamin D₃ that resists the catalytic activity of both CYP27B1 and CYP24A1.
    Rhieu SY; Annalora AJ; LaPorta E; Welsh J; Itoh T; Yamamoto K; Sakaki T; Chen TC; Uskokovic MR; Reddy GS
    J Cell Biochem; 2014 Aug; 115(8):1392-402. PubMed ID: 24535953
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 25-Dehydro-1alpha-hydroxyvitamin D3-26,23S-lactone antagonizes the nuclear vitamin D receptor by mediating a unique noncovalent conformational change.
    Bula CM; Bishop JE; Ishizuka S; Norman AW
    Mol Endocrinol; 2000 Nov; 14(11):1788-96. PubMed ID: 11075812
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.