356 related articles for article (PubMed ID: 27694307)
1. Distribution and effects of amino acid changes in drug-resistant α and β herpesviruses DNA polymerase.
Topalis D; Gillemot S; Snoeck R; Andrei G
Nucleic Acids Res; 2016 Nov; 44(20):9530-9554. PubMed ID: 27694307
[TBL] [Abstract][Full Text] [Related]
2. Amino acid changes within conserved region III of the herpes simplex virus and human cytomegalovirus DNA polymerases confer resistance to 4-oxo-dihydroquinolines, a novel class of herpesvirus antiviral agents.
Thomsen DR; Oien NL; Hopkins TA; Knechtel ML; Brideau RJ; Wathen MW; Homa FL
J Virol; 2003 Feb; 77(3):1868-76. PubMed ID: 12525621
[TBL] [Abstract][Full Text] [Related]
3. Thymidine kinase and protein kinase in drug-resistant herpesviruses: Heads of a Lernaean Hydra.
Topalis D; Gillemot S; Snoeck R; Andrei G
Drug Resist Updat; 2018 Mar; 37():1-16. PubMed ID: 29548479
[TBL] [Abstract][Full Text] [Related]
4. DNA polymerase mutations in drug-resistant herpes simplex virus mutants determine in vivo neurovirulence and drug-enzyme interactions.
Andrei G; Fiten P; Froeyen M; De Clercq E; Opdenakker G; Snoeck R
Antivir Ther; 2007; 12(5):719-32. PubMed ID: 17713155
[TBL] [Abstract][Full Text] [Related]
5. 4-Oxo-4,7-dihydrothieno[2,3-b]pyridines as non-nucleoside inhibitors of human cytomegalovirus and related herpesvirus polymerases.
Schnute ME; Cudahy MM; Brideau RJ; Homa FL; Hopkins TA; Knechtel ML; Oien NL; Pitts TW; Poorman RA; Wathen MW; Wieber JL
J Med Chem; 2005 Sep; 48(18):5794-804. PubMed ID: 16134946
[TBL] [Abstract][Full Text] [Related]
6. Differential impact of various substitutions at codon 715 in region II of HSV-1 and HCMV DNA polymerases.
Zarrouk K; Zhu X; Goyette N; Piret J; Shi R; Boivin G
Antiviral Res; 2021 Apr; 188():105046. PubMed ID: 33588012
[TBL] [Abstract][Full Text] [Related]
7. Contrasting effects of W781V and W780V mutations in helix N of herpes simplex virus 1 and human cytomegalovirus DNA polymerases on antiviral drug susceptibility.
Piret J; Goyette N; Eckenroth BE; Drouot E; Götte M; Boivin G
J Virol; 2015 Apr; 89(8):4636-44. PubMed ID: 25673718
[TBL] [Abstract][Full Text] [Related]
8. Drug resistance patterns of recombinant herpes simplex virus DNA polymerase mutants generated with a set of overlapping cosmids and plasmids.
Bestman-Smith J; Boivin G
J Virol; 2003 Jul; 77(14):7820-9. PubMed ID: 12829822
[TBL] [Abstract][Full Text] [Related]
9. In vitro-selected drug-resistant varicella-zoster virus mutants in the thymidine kinase and DNA polymerase genes yield novel phenotype-genotype associations and highlight differences between antiherpesvirus drugs.
Andrei G; Topalis D; Fiten P; McGuigan C; Balzarini J; Opdenakker G; Snoeck R
J Virol; 2012 Mar; 86(5):2641-52. PubMed ID: 22190713
[TBL] [Abstract][Full Text] [Related]
10. A mutation in the DNA polymerase accessory factor of herpes simplex virus 1 restores viral DNA replication in the presence of raltegravir.
Zhou B; Yang K; Wills E; Tang L; Baines JD
J Virol; 2014 Oct; 88(19):11121-9. PubMed ID: 25008933
[TBL] [Abstract][Full Text] [Related]
11. Cytomegalovirus antiviral resistance associated with treatment induced UL97 (protein kinase) and UL54 (DNA polymerase) mutations.
Scott GM; Isaacs MA; Zeng F; Kesson AM; Rawlinson WD
J Med Virol; 2004 Sep; 74(1):85-93. PubMed ID: 15258973
[TBL] [Abstract][Full Text] [Related]
12. Genotypic characterization of herpes simplex virus DNA polymerase UL42 processivity factor.
Burrel S; Aït-Arkoub Z; Agut H; Boutolleau D
Antiviral Res; 2012 Jan; 93(1):199-203. PubMed ID: 22061617
[TBL] [Abstract][Full Text] [Related]
13. Finger domain mutation affects enzyme activity, DNA replication efficiency, and fidelity of an exonuclease-deficient DNA polymerase of herpes simplex virus type 1.
Tian W; Hwang YT; Lu Q; Hwang CB
J Virol; 2009 Jul; 83(14):7194-201. PubMed ID: 19420083
[TBL] [Abstract][Full Text] [Related]
14. Inhibition of herpesvirus replication by 5-substituted 4'-thiopyrimidine nucleosides.
Prichard MN; Quenelle DC; Hartline CB; Harden EA; Jefferson G; Frederick SL; Daily SL; Whitley RJ; Tiwari KN; Maddry JA; Secrist JA; Kern ER
Antimicrob Agents Chemother; 2009 Dec; 53(12):5251-8. PubMed ID: 19770274
[TBL] [Abstract][Full Text] [Related]
15. An importin alpha/beta-recognized bipartite nuclear localization signal mediates targeting of the human herpes simplex virus type 1 DNA polymerase catalytic subunit pUL30 to the nucleus.
Alvisi G; Musiani D; Jans DA; Ripalti A
Biochemistry; 2007 Aug; 46(32):9155-63. PubMed ID: 17640102
[TBL] [Abstract][Full Text] [Related]
16. Evaluating phenotype and genotype of drug-resistant strains in herpesviruses.
Andrei G; Fiten P; De Clercq E; Snoeck R; Opdenakker G
Mol Biotechnol; 2001 Jun; 18(2):155-67. PubMed ID: 11471457
[TBL] [Abstract][Full Text] [Related]
17. Herpesvirus DNA polymerases: Structures, functions and inhibitors.
Zarrouk K; Piret J; Boivin G
Virus Res; 2017 Apr; 234():177-192. PubMed ID: 28153606
[TBL] [Abstract][Full Text] [Related]
18. Effects of Acyclovir, Foscarnet, and Ribonucleotides on Herpes Simplex Virus-1 DNA Polymerase: Mechanistic Insights and a Novel Mechanism for Preventing Stable Incorporation of Ribonucleotides into DNA.
Vashishtha AK; Kuchta RD
Biochemistry; 2016 Feb; 55(7):1168-77. PubMed ID: 26836009
[TBL] [Abstract][Full Text] [Related]
19. Resistance to antiviral inhibitors caused by the mutation S889A in the highly-conserved 885-GDTDS motif of the herpes simplex virus type 1 DNA polymerase.
Dorsky DI; Plourde C
Virology; 1993 Aug; 195(2):831-5. PubMed ID: 8337848
[TBL] [Abstract][Full Text] [Related]
20. Single nucleotide polymorphisms of thymidine kinase and DNA polymerase genes in clinical herpes simplex virus type 1 isolates associated with different resistance phenotypes.
Schubert A; Gentner E; Bohn K; Schwarz M; Mertens T; Sauerbrei A
Antiviral Res; 2014 Jul; 107():16-22. PubMed ID: 24747042
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
