BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

307 related articles for article (PubMed ID: 27694439)

  • 1. Mechanisms of Insertion of dCTP and dTTP Opposite the DNA Lesion O6-Methyl-2'-deoxyguanosine by Human DNA Polymerase η.
    Patra A; Zhang Q; Guengerich FP; Egli M
    J Biol Chem; 2016 Nov; 291(46):24304-24313. PubMed ID: 27694439
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural basis for proficient incorporation of dTTP opposite O6-methylguanine by human DNA polymerase iota.
    Pence MG; Choi JY; Egli M; Guengerich FP
    J Biol Chem; 2010 Dec; 285(52):40666-72. PubMed ID: 20961860
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular basis of selectivity of nucleoside triphosphate incorporation opposite O6-benzylguanine by sulfolobus solfataricus DNA polymerase Dpo4: steady-state and pre-steady-state kinetics and x-ray crystallography of correct and incorrect pairing.
    Eoff RL; Angel KC; Egli M; Guengerich FP
    J Biol Chem; 2007 May; 282(18):13573-84. PubMed ID: 17337730
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Efficient and high fidelity incorporation of dCTP opposite 7,8-dihydro-8-oxodeoxyguanosine by Sulfolobus solfataricus DNA polymerase Dpo4.
    Zang H; Irimia A; Choi JY; Angel KC; Loukachevitch LV; Egli M; Guengerich FP
    J Biol Chem; 2006 Jan; 281(4):2358-72. PubMed ID: 16306039
    [TBL] [Abstract][Full Text] [Related]  

  • 5. How Y-Family DNA polymerase IV is more accurate than Dpo4 at dCTP insertion opposite an N2-dG adduct of benzo[a]pyrene.
    Sholder G; Creech A; Loechler EL
    DNA Repair (Amst); 2015 Nov; 35():144-53. PubMed ID: 26523515
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Enzymatic bypass and the structural basis of miscoding opposite the DNA adduct 1,N
    Ghodke PP; Mali JR; Patra A; Rizzo CJ; Guengerich FP; Egli M
    J Biol Chem; 2021; 296():100642. PubMed ID: 33839151
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural Basis for Error-Free Bypass of the 5-N-Methylformamidopyrimidine-dG Lesion by Human DNA Polymerase η and Sulfolobus solfataricus P2 Polymerase IV.
    Patra A; Banerjee S; Johnson Salyard TL; Malik CK; Christov PP; Rizzo CJ; Stone MP; Egli M
    J Am Chem Soc; 2015 Jun; 137(22):7011-4. PubMed ID: 25988947
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural and Kinetic Analysis of Miscoding Opposite the DNA Adduct 1,N6-Ethenodeoxyadenosine by Human Translesion DNA Polymerase η.
    Patra A; Su Y; Zhang Q; Johnson KM; Guengerich FP; Egli M
    J Biol Chem; 2016 Jul; 291(27):14134-14145. PubMed ID: 27226627
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The abundant DNA adduct
    Njuma OJ; Su Y; Guengerich FP
    J Biol Chem; 2019 Jun; 294(26):10253-10265. PubMed ID: 31101656
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mechanism of error-free DNA synthesis across N1-methyl-deoxyadenosine by human DNA polymerase-ι.
    Jain R; Choudhury JR; Buku A; Johnson RE; Prakash L; Prakash S; Aggarwal AK
    Sci Rep; 2017 Mar; 7():43904. PubMed ID: 28272441
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sulfolobus solfataricus DNA polymerase Dpo4 is partially inhibited by "wobble" pairing between O6-methylguanine and cytosine, but accurate bypass is preferred.
    Eoff RL; Irimia A; Egli M; Guengerich FP
    J Biol Chem; 2007 Jan; 282(2):1456-67. PubMed ID: 17105728
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural and functional analysis of Sulfolobus solfataricus Y-family DNA polymerase Dpo4-catalyzed bypass of the malondialdehyde-deoxyguanosine adduct.
    Eoff RL; Stafford JB; Szekely J; Rizzo CJ; Egli M; Guengerich FP; Marnett LJ
    Biochemistry; 2009 Aug; 48(30):7079-88. PubMed ID: 19492857
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure and activity of Y-class DNA polymerase DPO4 from Sulfolobus solfataricus with templates containing the hydrophobic thymine analog 2,4-difluorotoluene.
    Irimia A; Eoff RL; Pallan PS; Guengerich FP; Egli M
    J Biol Chem; 2007 Dec; 282(50):36421-33. PubMed ID: 17951245
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Evidence for Watson-Crick and not Hoogsteen or wobble base pairing in the selection of nucleotides for insertion opposite pyrimidines and a thymine dimer by yeast DNA pol eta.
    Hwang H; Taylor JS
    Biochemistry; 2005 Mar; 44(12):4850-60. PubMed ID: 15779911
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Versatility of Y-family Sulfolobus solfataricus DNA polymerase Dpo4 in translesion synthesis past bulky N2-alkylguanine adducts.
    Zhang H; Eoff RL; Kozekov ID; Rizzo CJ; Egli M; Guengerich FP
    J Biol Chem; 2009 Feb; 284(6):3563-76. PubMed ID: 19059910
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural and kinetic analysis of nucleoside triphosphate incorporation opposite an abasic site by human translesion DNA polymerase η.
    Patra A; Zhang Q; Lei L; Su Y; Egli M; Guengerich FP
    J Biol Chem; 2015 Mar; 290(13):8028-38. PubMed ID: 25666608
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Kinetics, structure, and mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine bypass by human DNA polymerase η.
    Patra A; Nagy LD; Zhang Q; Su Y; Müller L; Guengerich FP; Egli M
    J Biol Chem; 2014 Jun; 289(24):16867-82. PubMed ID: 24759104
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mutagenic nucleotide incorporation and hindered translocation by a food carcinogen C8-dG adduct in Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4): modeling and dynamics studies.
    Zhang L; Rechkoblit O; Wang L; Patel DJ; Shapiro R; Broyde S
    Nucleic Acids Res; 2006; 34(11):3326-37. PubMed ID: 16820532
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Bypass of aflatoxin B1 adducts by the Sulfolobus solfataricus DNA polymerase IV.
    Banerjee S; Brown KL; Egli M; Stone MP
    J Am Chem Soc; 2011 Aug; 133(32):12556-68. PubMed ID: 21790157
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural and functional elucidation of the mechanism promoting error-prone synthesis by human DNA polymerase kappa opposite the 7,8-dihydro-8-oxo-2'-deoxyguanosine adduct.
    Irimia A; Eoff RL; Guengerich FP; Egli M
    J Biol Chem; 2009 Aug; 284(33):22467-22480. PubMed ID: 19542228
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.