BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 27695899)

  • 1. Sequential cleavage of insulin receptor by calpain 2 and γ-secretase impairs insulin signalling.
    Yuasa T; Amo-Shiinoki K; Ishikura S; Takahara M; Matsuoka T; Kaneto H; Kuroda A; Matsuhisa M; Hashida S
    Diabetologia; 2016 Dec; 59(12):2711-2721. PubMed ID: 27695899
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Insulin receptor cleavage induced by estrogen impairs insulin signaling.
    Yuasa T; Takata Y; Aki N; Kunimi K; Satoh M; Nii M; Izumi Y; Otoda T; Hashida S; Osawa H; Aihara KI
    BMJ Open Diabetes Res Care; 2021 Dec; 9(2):. PubMed ID: 34969688
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Development of in vitro model of insulin receptor cleavage induced by high glucose in HepG2 cells.
    Yuasa T; Amo K; Ishikura S; Nagaya H; Uchiyama K; Hashida S; Ebina Y
    Biochem Biophys Res Commun; 2014 Feb; 445(1):236-43. PubMed ID: 24508798
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Generation of intracellular domain of insulin receptor tyrosine kinase by gamma-secretase.
    Kasuga K; Kaneko H; Nishizawa M; Onodera O; Ikeuchi T
    Biochem Biophys Res Commun; 2007 Aug; 360(1):90-6. PubMed ID: 17577576
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A novel hepatokine, HFREP1, plays a crucial role in the development of insulin resistance and type 2 diabetes.
    Wu HT; Ou HY; Hung HC; Su YC; Lu FH; Wu JS; Yang YC; Wu CL; Chang CJ
    Diabetologia; 2016 Aug; 59(8):1732-42. PubMed ID: 27221093
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease.
    Ho L; Qin W; Pompl PN; Xiang Z; Wang J; Zhao Z; Peng Y; Cambareri G; Rocher A; Mobbs CV; Hof PR; Pasinetti GM
    FASEB J; 2004 May; 18(7):902-4. PubMed ID: 15033922
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Proton myo-inositol cotransporter is a novel γ-secretase associated protein that regulates Aβ production without affecting Notch cleavage.
    Teranishi Y; Inoue M; Yamamoto NG; Kihara T; Wiehager B; Ishikawa T; Winblad B; Schedin-Weiss S; Frykman S; Tjernberg LO
    FEBS J; 2015 Sep; 282(17):3438-51. PubMed ID: 26094765
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The beta secretase BACE1 regulates the expression of insulin receptor in the liver.
    Meakin PJ; Mezzapesa A; Benabou E; Haas ME; Bonardo B; Grino M; Brunel JM; Desbois-Mouthon C; Biddinger SB; Govers R; Ashford MLJ; Peiretti F
    Nat Commun; 2018 Apr; 9(1):1306. PubMed ID: 29610518
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The type III TGF-β receptor betaglycan transmembrane-cytoplasmic domain fragment is stable after ectodomain cleavage and is a substrate of the intramembrane protease γ-secretase.
    Blair CR; Stone JB; Wells RG
    Biochim Biophys Acta; 2011 Feb; 1813(2):332-9. PubMed ID: 21167215
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The insulin-like growth factor 1 (IGF-1) receptor is a substrate for gamma-secretase-mediated intramembrane proteolysis.
    McElroy B; Powell JC; McCarthy JV
    Biochem Biophys Res Commun; 2007 Jul; 358(4):1136-41. PubMed ID: 17524361
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cocoa flavonoids attenuate high glucose-induced insulin signalling blockade and modulate glucose uptake and production in human HepG2 cells.
    Cordero-Herrera I; Martín MÁ; Goya L; Ramos S
    Food Chem Toxicol; 2014 Feb; 64():10-9. PubMed ID: 24262486
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ADAM17 cleaves the insulin receptor ectodomain on endothelial cells and causes vascular insulin resistance.
    Ghiarone T; Castorena-Gonzalez JA; Foote CA; Ramirez-Perez FI; Ferreira-Santos L; Cabral-Amador FJ; de la Torre R; Ganga RR; Wheeler AA; Manrique-Acevedo C; Padilla J; Martinez-Lemus LA
    Am J Physiol Heart Circ Physiol; 2022 Oct; 323(4):H688-H701. PubMed ID: 36018759
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Proteomic profiling of gamma-secretase substrates and mapping of substrate requirements.
    Hemming ML; Elias JE; Gygi SP; Selkoe DJ
    PLoS Biol; 2008 Oct; 6(10):e257. PubMed ID: 18942891
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Combined thiazolidinedione-metformin treatment synergistically improves insulin signalling to insulin receptor substrate-1-dependent phosphatidylinositol 3-kinase, atypical protein kinase C and protein kinase B/Akt in human diabetic muscle.
    Temofonte N; Sajan MP; Nimal S; Pastoor T; Fumero C; Casaubon L; Powe JL; Standaert ML; Farese RV
    Diabetologia; 2009 Jan; 52(1):60-4. PubMed ID: 18972094
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hypoglycemic effects of Grifola frondosa (Maitake) polysaccharides F2 and F3 through improvement of insulin resistance in diabetic rats.
    Xiao C; Wu Q; Xie Y; Zhang J; Tan J
    Food Funct; 2015 Nov; 6(11):3567-75. PubMed ID: 26311233
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Insulin receptor deficits in schizophrenia and in cellular and animal models of insulin receptor dysfunction.
    Zhao Z; Ksiezak-Reding H; Riggio S; Haroutunian V; Pasinetti GM
    Schizophr Res; 2006 May; 84(1):1-14. PubMed ID: 16581231
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification and mutagenesis of the TACE and γ-secretase cleavage sites in the colony-stimulating factor 1 receptor.
    Vahidi A; Glenn G; van der Geer P
    Biochem Biophys Res Commun; 2014 Jul; 450(1):782-7. PubMed ID: 24955855
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Insulin resistance and increased pancreatic beta-cell proliferation in mice expressing a mutant insulin receptor (P1195L).
    Ogino J; Sakurai K; Yoshiwara K; Suzuki Y; Ishizuka N; Seki N; Suzuki Y; Koseki H; Shirasawa T; Hashimoto N; Yagui K; Saito Y
    J Endocrinol; 2006 Sep; 190(3):739-47. PubMed ID: 17003275
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Altered insulin receptor messenger ribonucleic acid splicing in liver is associated with deterioration of glucose tolerance in the spontaneously obese and diabetic rhesus monkey: analysis of controversy between monkey and human studies.
    Huang Z; Bodkin NL; Ortmeyer HK; Zenilman ME; Webster NJ; Hansen BC; Shuldiner AR
    J Clin Endocrinol Metab; 1996 Apr; 81(4):1552-6. PubMed ID: 8636366
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Insulin signalling in skeletal muscle of subjects with or without Type II-diabetes and first degree relatives of patients with the disease.
    Meyer MM; Levin K; Grimmsmann T; Beck-Nielsen H; Klein HH
    Diabetologia; 2002 Jun; 45(6):813-22. PubMed ID: 12107725
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.