These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

468 related articles for article (PubMed ID: 27697860)

  • 1. Absolute Amounts and Status of the Nrf2-Keap1-Cul3 Complex within Cells.
    Iso T; Suzuki T; Baird L; Yamamoto M
    Mol Cell Biol; 2016 Dec; 36(24):3100-3112. PubMed ID: 27697860
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2.
    Kobayashi A; Kang MI; Okawa H; Ohtsuji M; Zenke Y; Chiba T; Igarashi K; Yamamoto M
    Mol Cell Biol; 2004 Aug; 24(16):7130-9. PubMed ID: 15282312
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Zinc-binding triggers a conformational-switch in the cullin-3 substrate adaptor protein KEAP1 that controls transcription factor NRF2.
    McMahon M; Swift SR; Hayes JD
    Toxicol Appl Pharmacol; 2018 Dec; 360():45-57. PubMed ID: 30261176
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.
    Zhang DD; Lo SC; Cross JV; Templeton DJ; Hannink M
    Mol Cell Biol; 2004 Dec; 24(24):10941-53. PubMed ID: 15572695
    [TBL] [Abstract][Full Text] [Related]  

  • 5. CAND1-mediated substrate adaptor recycling is required for efficient repression of Nrf2 by Keap1.
    Lo SC; Hannink M
    Mol Cell Biol; 2006 Feb; 26(4):1235-44. PubMed ID: 16449638
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Diffusion dynamics of the Keap1-Cullin3 interaction in single live cells.
    Baird L; Dinkova-Kostova AT
    Biochem Biophys Res Commun; 2013 Mar; 433(1):58-65. PubMed ID: 23454126
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Antioxidant-induced INrf2 (Keap1) tyrosine 85 phosphorylation controls the nuclear export and degradation of the INrf2-Cul3-Rbx1 complex to allow normal Nrf2 activation and repression.
    Kaspar JW; Niture SK; Jaiswal AK
    J Cell Sci; 2012 Feb; 125(Pt 4):1027-38. PubMed ID: 22448038
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Keap1-Nrf2 system as an in vivo sensor for electrophiles.
    Uruno A; Motohashi H
    Nitric Oxide; 2011 Aug; 25(2):153-60. PubMed ID: 21385624
    [TBL] [Abstract][Full Text] [Related]  

  • 9. BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase.
    Furukawa M; Xiong Y
    Mol Cell Biol; 2005 Jan; 25(1):162-71. PubMed ID: 15601839
    [TBL] [Abstract][Full Text] [Related]  

  • 10. p97 Negatively Regulates NRF2 by Extracting Ubiquitylated NRF2 from the KEAP1-CUL3 E3 Complex.
    Tao S; Liu P; Luo G; Rojo de la Vega M; Chen H; Wu T; Tillotson J; Chapman E; Zhang DD
    Mol Cell Biol; 2017 Apr; 37(8):. PubMed ID: 28115426
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Arsenic induces NAD(P)H-quinone oxidoreductase I by disrupting the Nrf2 x Keap1 x Cul3 complex and recruiting Nrf2 x Maf to the antioxidant response element enhancer.
    He X; Chen MG; Lin GX; Ma Q
    J Biol Chem; 2006 Aug; 281(33):23620-31. PubMed ID: 16785233
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway.
    Zhang DD; Lo SC; Sun Z; Habib GM; Lieberman MW; Hannink M
    J Biol Chem; 2005 Aug; 280(34):30091-9. PubMed ID: 15983046
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase.
    Cullinan SB; Gordan JD; Jin J; Harper JW; Diehl JA
    Mol Cell Biol; 2004 Oct; 24(19):8477-86. PubMed ID: 15367669
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2.
    Sun Z; Zhang S; Chan JY; Zhang DD
    Mol Cell Biol; 2007 Sep; 27(18):6334-49. PubMed ID: 17636022
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Prothymosin-alpha mediates nuclear import of the INrf2/Cul3 Rbx1 complex to degrade nuclear Nrf2.
    Niture SK; Jaiswal AK
    J Biol Chem; 2009 May; 284(20):13856-13868. PubMed ID: 19279002
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular Basis of the KEAP1-NRF2 Signaling Pathway.
    Suzuki T; Takahashi J; Yamamoto M
    Mol Cells; 2023 Mar; 46(3):133-141. PubMed ID: 36994473
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy.
    Shibata T; Ohta T; Tong KI; Kokubu A; Odogawa R; Tsuta K; Asamura H; Yamamoto M; Hirohashi S
    Proc Natl Acad Sci U S A; 2008 Sep; 105(36):13568-73. PubMed ID: 18757741
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Gene-expression signature regulated by the KEAP1-NRF2-CUL3 axis is associated with a poor prognosis in head and neck squamous cell cancer.
    Namani A; Matiur Rahaman M; Chen M; Tang X
    BMC Cancer; 2018 Jan; 18(1):46. PubMed ID: 29306329
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Stress-sensing mechanisms and the physiological roles of the Keap1-Nrf2 system during cellular stress.
    Suzuki T; Yamamoto M
    J Biol Chem; 2017 Oct; 292(41):16817-16824. PubMed ID: 28842501
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural and biochemical characterization establishes a detailed understanding of KEAP1-CUL3 complex assembly.
    Adamson RJ; Payne NC; Bartual SG; Mazitschek R; Bullock AN
    Free Radic Biol Med; 2023 Aug; 204():215-225. PubMed ID: 37156295
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.