BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

2058 related articles for article (PubMed ID: 27698118)

  • 1. Activation of SAT1 engages polyamine metabolism with p53-mediated ferroptotic responses.
    Ou Y; Wang SJ; Li D; Chu B; Gu W
    Proc Natl Acad Sci U S A; 2016 Nov; 113(44):E6806-E6812. PubMed ID: 27698118
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Depletion of the polyamines spermidine and spermine by overexpression of spermidine/spermine N¹-acetyltransferase 1 (SAT1) leads to mitochondria-mediated apoptosis in mammalian cells.
    Mandal S; Mandal A; Park MH
    Biochem J; 2015 Jun; 468(3):435-47. PubMed ID: 25849284
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Lipoxygenase inhibitors protect acute lymphoblastic leukemia cells from ferroptotic cell death.
    Probst L; Dächert J; Schenk B; Fulda S
    Biochem Pharmacol; 2017 Sep; 140():41-52. PubMed ID: 28595877
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ferroptosis as a p53-mediated activity during tumour suppression.
    Jiang L; Kon N; Li T; Wang SJ; Su T; Hibshoosh H; Baer R; Gu W
    Nature; 2015 Apr; 520(7545):57-62. PubMed ID: 25799988
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Polyamine regulation of porcine reproductive and respiratory syndrome virus infection depends on spermidine-spermine acetyltransferase 1.
    Zhou Y; Hou Z; Fang L; Ke Q; Xiong Y; Fang P; Xiao S
    Vet Microbiol; 2020 Nov; 250():108839. PubMed ID: 33002680
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Coupling of the polyamine and iron metabolism pathways in the regulation of proliferation: Mechanistic links to alterations in key polyamine biosynthetic and catabolic enzymes.
    Lane DJR; Bae DH; Siafakas AR; Suryo Rahmanto Y; Al-Akra L; Jansson PJ; Casero RA; Richardson DR
    Biochim Biophys Acta Mol Basis Dis; 2018 Sep; 1864(9 Pt B):2793-2813. PubMed ID: 29777905
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Depletion of cellular polyamines, spermidine and spermine, causes a total arrest in translation and growth in mammalian cells.
    Mandal S; Mandal A; Johansson HE; Orjalo AV; Park MH
    Proc Natl Acad Sci U S A; 2013 Feb; 110(6):2169-74. PubMed ID: 23345430
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Spermidine/spermine N1-acetyltransferase-mediated polyamine catabolism regulates beige adipocyte biogenesis.
    Yuan F; Zhang L; Cao Y; Gao W; Zhao C; Fang Y; Zahedi K; Soleimani M; Lu X; Fang Z; Yang Q
    Metabolism; 2018 Aug; 85():298-304. PubMed ID: 29715464
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation of polyamine catabolism promotes glutamine metabolism and creates a targetable vulnerability in lung cancer.
    Han X; Wang D; Yang L; Wang N; Shen J; Wang J; Zhang L; Chen L; Gao S; Zong WX; Wang Y
    Proc Natl Acad Sci U S A; 2024 Mar; 121(13):e2319429121. PubMed ID: 38513095
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Spermidine/spermine-N(1)-acetyltransferase: a key metabolic regulator.
    Pegg AE
    Am J Physiol Endocrinol Metab; 2008 Jun; 294(6):E995-1010. PubMed ID: 18349109
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Continuous oxidative stress due to activation of polyamine catabolism accelerates aging and protects against hepatotoxic insults.
    Cerrada-Gimenez M; Pietilä M; Loimas S; Pirinen E; Hyvönen MT; Keinänen TA; Jänne J; Alhonen L
    Transgenic Res; 2011 Apr; 20(2):387-96. PubMed ID: 20577801
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The tumor suppressor protein p53 and the ferroptosis network.
    Kang R; Kroemer G; Tang D
    Free Radic Biol Med; 2019 Mar; 133():162-168. PubMed ID: 29800655
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The MUC1-HIF-1α signaling axis regulates pancreatic cancer pathogenesis through polyamine metabolism remodeling.
    Murthy D; Attri KS; Suresh V; Rajacharya GH; Valenzuela CA; Thakur R; Zhao J; Shukla SK; Chaika NV; LaBreck D; Rao CV; Hollingsworth MA; Mehla K; Singh PK
    Proc Natl Acad Sci U S A; 2024 Apr; 121(14):e2315509121. PubMed ID: 38547055
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The polyamine catabolic enzyme SAT1 modulates tumorigenesis and radiation response in GBM.
    Brett-Morris A; Wright BM; Seo Y; Pasupuleti V; Zhang J; Lu J; Spina R; Bar EE; Gujrati M; Schur R; Lu ZR; Welford SM
    Cancer Res; 2014 Dec; 74(23):6925-34. PubMed ID: 25277523
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Reduction in polyamine catabolism leads to spermine-mediated airway epithelial injury and induces asthma features.
    Jain V; Raina S; Gheware AP; Singh R; Rehman R; Negi V; Murray Stewart T; Mabalirajan U; Mishra AK; Casero RA; Agrawal A; Ghosh B
    Allergy; 2018 Oct; 73(10):2033-2045. PubMed ID: 29729200
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interferon-Induced Spermidine-Spermine Acetyltransferase and Polyamine Depletion Restrict Zika and Chikungunya Viruses.
    Mounce BC; Poirier EZ; Passoni G; Simon-Loriere E; Cesaro T; Prot M; Stapleford KA; Moratorio G; Sakuntabhai A; Levraud JP; Vignuzzi M
    Cell Host Microbe; 2016 Aug; 20(2):167-77. PubMed ID: 27427208
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Growth arrest- and polyamine-dependent expression of spermidine/spermine N1-acetyltransferase in human tumor cells.
    Ignatenko NA; Gerner EW
    Cell Growth Differ; 1996 Apr; 7(4):481-6. PubMed ID: 9052989
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Acetylation Is Crucial for p53-Mediated Ferroptosis and Tumor Suppression.
    Wang SJ; Li D; Ou Y; Jiang L; Chen Y; Zhao Y; Gu W
    Cell Rep; 2016 Oct; 17(2):366-373. PubMed ID: 27705786
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation of SSAT1/ALOX15 Axis Aggravates Cerebral Ischemia/Reperfusion Injury via Triggering Neuronal Ferroptosis.
    Zhao J; Wu Y; Liang S; Piao X
    Neuroscience; 2022 Mar; 485():78-90. PubMed ID: 35090880
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Polyamine catabolism is concentrated in tumor-associated histiocytes in diffuse large B-cell lymphoma and classic Hodgkin lymphoma.
    Bronson AS; Lilley CM; Zleczewski M; Mirza KM
    Pathol Res Pract; 2023 Aug; 248():154627. PubMed ID: 37343378
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 103.