633 related articles for article (PubMed ID: 27708104)
1. High-resolution interrogation of functional elements in the noncoding genome.
Sanjana NE; Wright J; Zheng K; Shalem O; Fontanillas P; Joung J; Cheng C; Regev A; Zhang F
Science; 2016 Sep; 353(6307):1545-1549. PubMed ID: 27708104
[TBL] [Abstract][Full Text] [Related]
2. Genome-scale CRISPR-Cas9 knockout screening in human cells.
Shalem O; Sanjana NE; Hartenian E; Shi X; Scott DA; Mikkelson T; Heckl D; Ebert BL; Root DE; Doench JG; Zhang F
Science; 2014 Jan; 343(6166):84-87. PubMed ID: 24336571
[TBL] [Abstract][Full Text] [Related]
3. Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood.
Joung J; Engreitz JM; Konermann S; Abudayyeh OO; Verdine VK; Aguet F; Gootenberg JS; Sanjana NE; Wright JB; Fulco CP; Tseng YY; Yoon CH; Boehm JS; Lander ES; Zhang F
Nature; 2017 Aug; 548(7667):343-346. PubMed ID: 28792927
[TBL] [Abstract][Full Text] [Related]
4. Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex.
Konermann S; Brigham MD; Trevino AE; Joung J; Abudayyeh OO; Barcena C; Hsu PD; Habib N; Gootenberg JS; Nishimasu H; Nureki O; Zhang F
Nature; 2015 Jan; 517(7536):583-8. PubMed ID: 25494202
[TBL] [Abstract][Full Text] [Related]
5. CRISPR Screens Identify Essential Cell Growth Mediators in BRAF Inhibitor-resistant Melanoma.
Li Z; Wang B; Gu S; Jiang P; Sahu A; Chen CH; Han T; Shi S; Wang X; Traugh N; Liu H; Liu Y; Wu Q; Brown M; Xiao T; Boland GM; Shirley Liu X
Genomics Proteomics Bioinformatics; 2020 Feb; 18(1):26-40. PubMed ID: 32413516
[TBL] [Abstract][Full Text] [Related]
6. High-Throughput Approaches to Pinpoint Function within the Noncoding Genome.
Montalbano A; Canver MC; Sanjana NE
Mol Cell; 2017 Oct; 68(1):44-59. PubMed ID: 28985510
[TBL] [Abstract][Full Text] [Related]
7. Enhancer-targeted genome editing selectively blocks innate resistance to oncokinase inhibition.
Webster DE; Barajas B; Bussat RT; Yan KJ; Neela PH; Flockhart RJ; Kovalski J; Zehnder A; Khavari PA
Genome Res; 2014 May; 24(5):751-60. PubMed ID: 24443471
[TBL] [Abstract][Full Text] [Related]
8. Vemurafenib.
Flaherty KT; Yasothan U; Kirkpatrick P
Nat Rev Drug Discov; 2011 Oct; 10(11):811-2. PubMed ID: 22037033
[TBL] [Abstract][Full Text] [Related]
9. Identification of multiple mechanisms of resistance to vemurafenib in a patient with BRAFV600E-mutated cutaneous melanoma successfully rechallenged after progression.
Romano E; Pradervand S; Paillusson A; Weber J; Harshman K; Muehlethaler K; Speiser D; Peters S; Rimoldi D; Michielin O
Clin Cancer Res; 2013 Oct; 19(20):5749-57. PubMed ID: 23948972
[TBL] [Abstract][Full Text] [Related]
10. Mechanisms of resistance to RAF inhibition in melanomas harboring a BRAF mutation.
Chapman PB
Am Soc Clin Oncol Educ Book; 2013; ():. PubMed ID: 23714462
[TBL] [Abstract][Full Text] [Related]
11. Creation of Novel Protein Variants with CRISPR/Cas9-Mediated Mutagenesis: Turning a Screening By-Product into a Discovery Tool.
Donovan KF; Hegde M; Sullender M; Vaimberg EW; Johannessen CM; Root DE; Doench JG
PLoS One; 2017; 12(1):e0170445. PubMed ID: 28118392
[TBL] [Abstract][Full Text] [Related]
12. The discovery of vemurafenib for the treatment of BRAF-mutated metastatic melanoma.
Kim A; Cohen MS
Expert Opin Drug Discov; 2016 Sep; 11(9):907-16. PubMed ID: 27327499
[TBL] [Abstract][Full Text] [Related]
13. PDGFRα up-regulation mediated by sonic hedgehog pathway activation leads to BRAF inhibitor resistance in melanoma cells with BRAF mutation.
Sabbatino F; Wang Y; Wang X; Flaherty KT; Yu L; Pepin D; Scognamiglio G; Pepe S; Kirkwood JM; Cooper ZA; Frederick DT; Wargo JA; Ferrone S; Ferrone CR
Oncotarget; 2014 Apr; 5(7):1926-41. PubMed ID: 24732172
[TBL] [Abstract][Full Text] [Related]
14. [Cellular and molecular mechanisms of carcinogenic side effects and resistance to BRAF inhibitors in metastatic melanoma with BRAFV600 mutation: state of the knowledge].
Capovilla M
Ann Pathol; 2013 Dec; 33(6):375-85. PubMed ID: 24331719
[TBL] [Abstract][Full Text] [Related]
15. Elucidating distinct roles for NF1 in melanomagenesis.
Maertens O; Johnson B; Hollstein P; Frederick DT; Cooper ZA; Messiaen L; Bronson RT; McMahon M; Granter S; Flaherty K; Wargo JA; Marais R; Cichowski K
Cancer Discov; 2013 Mar; 3(3):338-49. PubMed ID: 23171796
[TBL] [Abstract][Full Text] [Related]
16. BRAF
Lunavat TR; Cheng L; Einarsdottir BO; Olofsson Bagge R; Veppil Muralidharan S; Sharples RA; Lässer C; Gho YS; Hill AF; Nilsson JA; Lötvall J
Proc Natl Acad Sci U S A; 2017 Jul; 114(29):E5930-E5939. PubMed ID: 28684402
[TBL] [Abstract][Full Text] [Related]
17. Efficacy of vemurafenib in a trametinib-resistant stage IV melanoma patient--letter.
Bernhardt M; Orouji E; Larribere L; Gebhardt C; Utikal J
Clin Cancer Res; 2014 May; 20(9):2498-9. PubMed ID: 24789037
[No Abstract] [Full Text] [Related]
18. COT drives resistance to RAF inhibition through MAP kinase pathway reactivation.
Johannessen CM; Boehm JS; Kim SY; Thomas SR; Wardwell L; Johnson LA; Emery CM; Stransky N; Cogdill AP; Barretina J; Caponigro G; Hieronymus H; Murray RR; Salehi-Ashtiani K; Hill DE; Vidal M; Zhao JJ; Yang X; Alkan O; Kim S; Harris JL; Wilson CJ; Myer VE; Finan PM; Root DE; Roberts TM; Golub T; Flaherty KT; Dummer R; Weber BL; Sellers WR; Schlegel R; Wargo JA; Hahn WC; Garraway LA
Nature; 2010 Dec; 468(7326):968-72. PubMed ID: 21107320
[TBL] [Abstract][Full Text] [Related]
19. The genetic landscape of clinical resistance to RAF inhibition in metastatic melanoma.
Van Allen EM; Wagle N; Sucker A; Treacy DJ; Johannessen CM; Goetz EM; Place CS; Taylor-Weiner A; Whittaker S; Kryukov GV; Hodis E; Rosenberg M; McKenna A; Cibulskis K; Farlow D; Zimmer L; Hillen U; Gutzmer R; Goldinger SM; Ugurel S; Gogas HJ; Egberts F; Berking C; Trefzer U; Loquai C; Weide B; Hassel JC; Gabriel SB; Carter SL; Getz G; Garraway LA; Schadendorf D;
Cancer Discov; 2014 Jan; 4(1):94-109. PubMed ID: 24265153
[TBL] [Abstract][Full Text] [Related]
20. Targeting hyperactivation of the AKT survival pathway to overcome therapy resistance of melanoma brain metastases.
Niessner H; Forschner A; Klumpp B; Honegger JB; Witte M; Bornemann A; Dummer R; Adam A; Bauer J; Tabatabai G; Flaherty K; Sinnberg T; Beck D; Leiter U; Mauch C; Roesch A; Weide B; Eigentler T; Schadendorf D; Garbe C; Kulms D; Quintanilla-Martinez L; Meier F
Cancer Med; 2013 Feb; 2(1):76-85. PubMed ID: 24133630
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
