BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

292 related articles for article (PubMed ID: 27709006)

  • 1. An update on the role of intestinal cytochrome P450 enzymes in drug disposition.
    Xie F; Ding X; Zhang QY
    Acta Pharm Sin B; 2016 Sep; 6(5):374-383. PubMed ID: 27709006
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Role of intestinal cytochrome P450 (P450) in modulating the bioavailability of oral lovastatin: insights from studies on the intestinal epithelium-specific P450 reductase knockout mouse.
    Zhu Y; D'Agostino J; Zhang QY
    Drug Metab Dispos; 2011 Jun; 39(6):939-43. PubMed ID: 21349922
    [TBL] [Abstract][Full Text] [Related]  

  • 3. An intestinal epithelium-specific cytochrome P450 (P450) reductase-knockout mouse model: direct evidence for a role of intestinal p450s in first-pass clearance of oral nifedipine.
    Zhang QY; Fang C; Zhang J; Dunbar D; Kaminsky L; Ding X
    Drug Metab Dispos; 2009 Mar; 37(3):651-7. PubMed ID: 19056912
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation of intestinal cytochrome P450 expression by hepatic cytochrome P450: possible involvement of fibroblast growth factor 15 and impact on systemic drug exposure.
    Zhu Y; Ding X; Fang C; Zhang QY
    Mol Pharmacol; 2014 Jan; 85(1):139-47. PubMed ID: 24184963
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effect of Cytochrome P450 Reductase Deficiency on 2-Amino-9H-pyrido[2,3-b]indole Metabolism and DNA Adduct Formation in Liver and Extrahepatic Tissues of Mice.
    Turesky RJ; Konorev D; Fan X; Tang Y; Yao L; Ding X; Xie F; Zhu Y; Zhang QY
    Chem Res Toxicol; 2015 Dec; 28(12):2400-10. PubMed ID: 26583703
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Role of small intestinal cytochromes p450 in the bioavailability of oral nifedipine.
    Zhang QY; Kaminsky LS; Dunbar D; Zhang J; Ding X
    Drug Metab Dispos; 2007 Sep; 35(9):1617-23. PubMed ID: 17567730
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Contributions of Hepatic and Intestinal Metabolism to the Disposition of Niclosamide, a Repurposed Drug with Poor Bioavailability.
    Fan X; Li H; Ding X; Zhang QY
    Drug Metab Dispos; 2019 Jul; 47(7):756-763. PubMed ID: 31040114
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A mouse model with liver-specific deletion and global suppression of the NADPH-cytochrome P450 reductase gene: characterization and utility for in vivo studies of cyclophosphamide disposition.
    Gu J; Chen CS; Wei Y; Fang C; Xie F; Kannan K; Yang W; Waxman DJ; Ding X
    J Pharmacol Exp Ther; 2007 Apr; 321(1):9-17. PubMed ID: 17218484
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The role of small-intestinal P450 enzymes in protection against systemic exposure of orally administered benzo[a]pyrene.
    Fang C; Zhang QY
    J Pharmacol Exp Ther; 2010 Jul; 334(1):156-63. PubMed ID: 20400470
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role of hepatic and intestinal p450 enzymes in the metabolic activation of the colon carcinogen azoxymethane in mice.
    Megaraj V; Ding X; Fang C; Kovalchuk N; Zhu Y; Zhang QY
    Chem Res Toxicol; 2014 Apr; 27(4):656-62. PubMed ID: 24552495
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of hepatic and intestinal cytochrome P450 3A and 2B6 in the metabolism, disposition, and miotic effects of methadone.
    Kharasch ED; Hoffer C; Whittington D; Sheffels P
    Clin Pharmacol Ther; 2004 Sep; 76(3):250-69. PubMed ID: 15371986
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of intestinal cytochrome p450 enzymes in diclofenac-induced toxicity in the small intestine.
    Zhu Y; Zhang QY
    J Pharmacol Exp Ther; 2012 Nov; 343(2):362-70. PubMed ID: 22892338
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Adaptive hepatic and intestinal alterations in mice after deletion of NADPH-cytochrome P450 Oxidoreductase (Cpr) in hepatocytes.
    Cheng X; Gu J; Klaassen CD
    Drug Metab Dispos; 2014 Nov; 42(11):1826-33. PubMed ID: 25147274
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Utilizing in vitro and PBPK tools to link ADME characteristics to plasma profiles: case example nifedipine immediate release formulation.
    Wagner C; Thelen K; Willmann S; Selen A; Dressman JB
    J Pharm Sci; 2013 Sep; 102(9):3205-19. PubMed ID: 23696038
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Exposure-dependent inhibition of intestinal and hepatic CYP3A4 in vivo by grapefruit juice.
    Veronese ML; Gillen LP; Burke JP; Dorval EP; Hauck WW; Pequignot E; Waldman SA; Greenberg HE
    J Clin Pharmacol; 2003 Aug; 43(8):831-9. PubMed ID: 12953340
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In Vitro Human Cell-Based Experimental Models for the Evaluation of Enteric Metabolism and Drug Interaction Potential of Drugs and Natural Products.
    Li AP
    Drug Metab Dispos; 2020 Oct; 48(10):980-992. PubMed ID: 32636209
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cytochrome P450-mediated metabolism in the human gut wall.
    Thelen K; Dressman JB
    J Pharm Pharmacol; 2009 May; 61(5):541-58. PubMed ID: 19405992
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Narcotic drugs change the expression of cytochrome P450 2E1 and 2C6 and other activities of carcinogen-metabolizing enzymes in the liver of male mice.
    Sheweita SA
    Toxicology; 2003 Sep; 191(2-3):133-42. PubMed ID: 12965116
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Determination of the role of target tissue metabolism in lung carcinogenesis using conditional cytochrome P450 reductase-null mice.
    Weng Y; Fang C; Turesky RJ; Behr M; Kaminsky LS; Ding X
    Cancer Res; 2007 Aug; 67(16):7825-32. PubMed ID: 17699788
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Intestinal epithelium-specific knockout of the cytochrome P450 reductase gene exacerbates dextran sulfate sodium-induced colitis.
    Zhu Y; Xie F; Ding L; Fan X; Ding X; Zhang QY
    J Pharmacol Exp Ther; 2015 Jul; 354(1):10-7. PubMed ID: 25926522
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.