These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
439 related articles for article (PubMed ID: 27712045)
1. Systematic Analysis of Tyrosine Kinase Inhibitor Response to RET Gatekeeper Mutations in Thyroid Cancer. Meng S; Wu H; Wang J; Qiu Q Mol Inform; 2016 Oct; 35(10):495-505. PubMed ID: 27712045 [TBL] [Abstract][Full Text] [Related]
2. Role of RET protein-tyrosine kinase inhibitors in the treatment RET-driven thyroid and lung cancers. Roskoski R; Sadeghi-Nejad A Pharmacol Res; 2018 Feb; 128():1-17. PubMed ID: 29284153 [TBL] [Abstract][Full Text] [Related]
3. Alectinib shows potent antitumor activity against RET-rearranged non-small cell lung cancer. Kodama T; Tsukaguchi T; Satoh Y; Yoshida M; Watanabe Y; Kondoh O; Sakamoto H Mol Cancer Ther; 2014 Dec; 13(12):2910-8. PubMed ID: 25349307 [TBL] [Abstract][Full Text] [Related]
4. Ponatinib (AP24534) is a novel potent inhibitor of oncogenic RET mutants associated with thyroid cancer. De Falco V; Buonocore P; Muthu M; Torregrossa L; Basolo F; Billaud M; Gozgit JM; Carlomagno F; Santoro M J Clin Endocrinol Metab; 2013 May; 98(5):E811-9. PubMed ID: 23526464 [TBL] [Abstract][Full Text] [Related]
5. Ponatinib is a potent inhibitor of wild-type and drug-resistant gatekeeper mutant RET kinase. Mologni L; Redaelli S; Morandi A; Plaza-Menacho I; Gambacorti-Passerini C Mol Cell Endocrinol; 2013 Sep; 377(1-2):1-6. PubMed ID: 23811235 [TBL] [Abstract][Full Text] [Related]
6. Drug resistance profiles of mutations in the RET kinase domain. Liu X; Shen T; Mooers BHM; Hilberg F; Wu J Br J Pharmacol; 2018 Sep; 175(17):3504-3515. PubMed ID: 29908090 [TBL] [Abstract][Full Text] [Related]
7. A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants. Yoon H; Kwak Y; Choi S; Cho H; Kim ND; Sim T J Med Chem; 2016 Jan; 59(1):358-73. PubMed ID: 26652860 [TBL] [Abstract][Full Text] [Related]
8. Discovery of 4-methyl-N-(4-((4-methylpiperazin- 1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-oxy)benzamide as a potent inhibitor of RET and its gatekeeper mutant. Li X; Su J; Yang Y; Lian W; Deng Z; Yang Z; Chen G; Zhang B; Dong C; Liu X; Li L; Wang Z; Hu Z; Xu Q; Deng X Eur J Med Chem; 2020 Dec; 207():112755. PubMed ID: 32882611 [TBL] [Abstract][Full Text] [Related]
9. Challenging clinically unresponsive medullary thyroid cancer: Discovery and pharmacological activity of novel RET inhibitors. La Pietra V; Sartini S; Botta L; Antonelli A; Ferrari SM; Fallahi P; Moriconi A; Coviello V; Quattrini L; Ke YY; Hsing-Pang H; Da Settimo F; Novellino E; La Motta C; Marinelli L Eur J Med Chem; 2018 Apr; 150():491-505. PubMed ID: 29549836 [TBL] [Abstract][Full Text] [Related]
10. The molecular basis for RET tyrosine-kinase inhibitors in thyroid cancer. De Falco V; Carlomagno F; Li HY; Santoro M Best Pract Res Clin Endocrinol Metab; 2017 Jun; 31(3):307-318. PubMed ID: 28911727 [TBL] [Abstract][Full Text] [Related]
11. Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants. Yang J; Chen K; Zhang G; Yang QY; Li YS; Huang SZ; Wang YL; Yang W; Jiang XJ; Yan HX; Zhu JQ; Xiang R; Luo YF; Li WM; Wei YQ; Li LL; Yang SY Eur J Med Chem; 2018 Jan; 143():1148-1164. PubMed ID: 29133048 [TBL] [Abstract][Full Text] [Related]
12. In silico profiling and structural insights of missense mutations in RET protein kinase domain by molecular dynamics and docking approach. George Priya Doss C; Rajith B; Chakraboty C; Balaji V; Magesh R; Gowthami B; Menon S; Swati M; Trivedi M; Paul J; Vasan R; Das M Mol Biosyst; 2014 Mar; 10(3):421-36. PubMed ID: 24336963 [TBL] [Abstract][Full Text] [Related]
13. Selective RET kinase inhibition for patients with RET-altered cancers. Subbiah V; Velcheti V; Tuch BB; Ebata K; Busaidy NL; Cabanillas ME; Wirth LJ; Stock S; Smith S; Lauriault V; Corsi-Travali S; Henry D; Burkard M; Hamor R; Bouhana K; Winski S; Wallace RD; Hartley D; Rhodes S; Reddy M; Brandhuber BJ; Andrews S; Rothenberg SM; Drilon A Ann Oncol; 2018 Aug; 29(8):1869-1876. PubMed ID: 29912274 [TBL] [Abstract][Full Text] [Related]
14. Emergence of RET rearrangement co-existing with activated EGFR mutation in EGFR-mutated NSCLC patients who had progressed on first- or second-generation EGFR TKI. Klempner SJ; Bazhenova LA; Braiteh FS; Nikolinakos PG; Gowen K; Cervantes CM; Chmielecki J; Greenbowe JR; Ross JS; Stephens PJ; Miller VA; Ali SM; Ou SH Lung Cancer; 2015 Sep; 89(3):357-9. PubMed ID: 26187428 [TBL] [Abstract][Full Text] [Related]
15. Targeting RET for thyroid cancer therapy. Lanzi C; Cassinelli G; Nicolini V; Zunino F Biochem Pharmacol; 2009 Feb; 77(3):297-309. PubMed ID: 19028457 [TBL] [Abstract][Full Text] [Related]
16. Combination of In Silico Analysis and In Vitro Assay to Investigate Drug Response to Human Epidermal Growth Factor Receptor 2 Mutations in Lung Cancer. Yu X; Wang T; Lou Y; Li Y Mol Inform; 2016 Jan; 35(1):25-35. PubMed ID: 27491651 [TBL] [Abstract][Full Text] [Related]
17. Precision Targeted Therapy with BLU-667 for Subbiah V; Gainor JF; Rahal R; Brubaker JD; Kim JL; Maynard M; Hu W; Cao Q; Sheets MP; Wilson D; Wilson KJ; DiPietro L; Fleming P; Palmer M; Hu MI; Wirth L; Brose MS; Ou SI; Taylor M; Garralda E; Miller S; Wolf B; Lengauer C; Guzi T; Evans EK Cancer Discov; 2018 Jul; 8(7):836-849. PubMed ID: 29657135 [TBL] [Abstract][Full Text] [Related]
18. Targeting RET receptor tyrosine kinase activation in cancer. Phay JE; Shah MH Clin Cancer Res; 2010 Dec; 16(24):5936-41. PubMed ID: 20930041 [TBL] [Abstract][Full Text] [Related]
19. Structural basis of acquired resistance to selpercatinib and pralsetinib mediated by non-gatekeeper RET mutations. Subbiah V; Shen T; Terzyan SS; Liu X; Hu X; Patel KP; Hu M; Cabanillas M; Behrang A; Meric-Bernstam F; Vo PTT; Mooers BHM; Wu J Ann Oncol; 2021 Feb; 32(2):261-268. PubMed ID: 33161056 [TBL] [Abstract][Full Text] [Related]
20. RET fusions in solid tumors. Li AY; McCusker MG; Russo A; Scilla KA; Gittens A; Arensmeyer K; Mehra R; Adamo V; Rolfo C Cancer Treat Rev; 2019 Dec; 81():101911. PubMed ID: 31715421 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]