These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Inhibition of EGFR or IGF-1R signaling enhances radiation response in head and neck cancer models but concurrent inhibition has no added benefit. Raju U; Molkentine DP; Valdecanas DR; Deorukhkar A; Mason KA; Buchholz TA; Meyn RE; Ang KK; Skinner H Cancer Med; 2015 Jan; 4(1):65-74. PubMed ID: 25355701 [TBL] [Abstract][Full Text] [Related]
3. Insulin-like growth factor-1 receptor inhibition induces a resistance mechanism via the epidermal growth factor receptor/HER3/AKT signaling pathway: rational basis for cotargeting insulin-like growth factor-1 receptor and epidermal growth factor receptor in hepatocellular carcinoma. Desbois-Mouthon C; Baron A; Blivet-Van Eggelpoël MJ; Fartoux L; Venot C; Bladt F; Housset C; Rosmorduc O Clin Cancer Res; 2009 Sep; 15(17):5445-56. PubMed ID: 19706799 [TBL] [Abstract][Full Text] [Related]
4. [Relationship between the insulin-like growth factor 1 receptor signaling pathway and the resistance of nasopharyngeal carcinoma to cetuximab]. Zuo Q; Luo RC Zhonghua Zhong Liu Za Zhi; 2010 Aug; 32(8):575-9. PubMed ID: 21122407 [TBL] [Abstract][Full Text] [Related]
5. Signaling via ErbB2 and ErbB3 associates with resistance and epidermal growth factor receptor (EGFR) amplification with sensitivity to EGFR inhibitor gefitinib in head and neck squamous cell carcinoma cells. Erjala K; Sundvall M; Junttila TT; Zhang N; Savisalo M; Mali P; Kulmala J; Pulkkinen J; Grenman R; Elenius K Clin Cancer Res; 2006 Jul; 12(13):4103-11. PubMed ID: 16818711 [TBL] [Abstract][Full Text] [Related]
6. XGFR*, a novel affinity-matured bispecific antibody targeting IGF-1R and EGFR with combined signaling inhibition and enhanced immune activation for the treatment of pancreatic cancer. Schanzer JM; Wartha K; Moessner E; Hosse RJ; Moser S; Croasdale R; Trochanowska H; Shao C; Wang P; Shi L; Weinzierl T; Rieder N; Bacac M; Ries CH; Kettenberger H; Schlothauer T; Friess T; Umana P; Klein C MAbs; 2016; 8(4):811-27. PubMed ID: 26984378 [TBL] [Abstract][Full Text] [Related]
7. Growth and molecular interactions of the anti-EGFR antibody cetuximab and the DNA cross-linking agent cisplatin in gefitinib-resistant MDA-MB-468 cells: new prospects in the treatment of triple-negative/basal-like breast cancer. Oliveras-Ferraros C; Vazquez-Martin A; López-Bonet E; Martín-Castillo B; Del Barco S; Brunet J; Menendez JA Int J Oncol; 2008 Dec; 33(6):1165-76. PubMed ID: 19020749 [TBL] [Abstract][Full Text] [Related]
8. Insulin receptor substrate-1 involvement in epidermal growth factor receptor and insulin-like growth factor receptor signalling: implication for Gefitinib ('Iressa') response and resistance. Knowlden JM; Jones HE; Barrow D; Gee JM; Nicholson RI; Hutcheson IR Breast Cancer Res Treat; 2008 Sep; 111(1):79-91. PubMed ID: 17902048 [TBL] [Abstract][Full Text] [Related]
9. Insulin-like growth factor-I receptor signaling in tamoxifen-resistant breast cancer: a supporting role to the epidermal growth factor receptor. Knowlden JM; Hutcheson IR; Barrow D; Gee JM; Nicholson RI Endocrinology; 2005 Nov; 146(11):4609-18. PubMed ID: 16037379 [TBL] [Abstract][Full Text] [Related]
14. Reduced expression of EI24 confers resistance to gefitinib through IGF-1R signaling in PC9 NSCLC cells. Choi JM; Jang JY; Choi YR; Kim HR; Cho BC; Lee HW Lung Cancer; 2015 Nov; 90(2):175-81. PubMed ID: 26342551 [TBL] [Abstract][Full Text] [Related]
15. Dual-agent molecular targeting of the epidermal growth factor receptor (EGFR): combining anti-EGFR antibody with tyrosine kinase inhibitor. Huang S; Armstrong EA; Benavente S; Chinnaiyan P; Harari PM Cancer Res; 2004 Aug; 64(15):5355-62. PubMed ID: 15289342 [TBL] [Abstract][Full Text] [Related]
16. Combating resistance to anti-IGFR antibody by targeting the integrin β3-Src pathway. Shin DH; Lee HJ; Min HY; Choi SP; Lee MS; Lee JW; Johnson FM; Mehta K; Lippman SM; Glisson BS; Lee HY J Natl Cancer Inst; 2013 Oct; 105(20):1558-70. PubMed ID: 24092920 [TBL] [Abstract][Full Text] [Related]
17. Picropodophyllin inhibits proliferation and survival of diffuse large B-cell lymphoma cells. Strömberg T; Feng X; Delforoush M; Berglund M; Lin Y; Axelson M; Larsson O; Georgii-Hemming P; Lennartsson J; Enblad G Med Oncol; 2015 Jul; 32(7):188. PubMed ID: 26021470 [TBL] [Abstract][Full Text] [Related]
18. Inhibition of tumor growth by targeted anti-EGFR/IGF-1R nanobullets depends on efficient blocking of cell survival pathways. van der Meel R; Oliveira S; Altintas I; Heukers R; Pieters EH; van Bergen en Henegouwen PM; Storm G; Hennink WE; Kok RJ; Schiffelers RM Mol Pharm; 2013 Oct; 10(10):3717-27. PubMed ID: 23889133 [TBL] [Abstract][Full Text] [Related]
19. A novel glycoengineered bispecific antibody format for targeted inhibition of epidermal growth factor receptor (EGFR) and insulin-like growth factor receptor type I (IGF-1R) demonstrating unique molecular properties. Schanzer JM; Wartha K; Croasdale R; Moser S; Künkele KP; Ries C; Scheuer W; Duerr H; Pompiati S; Pollman J; Stracke J; Lau W; Ries S; Brinkmann U; Klein C; Umana P J Biol Chem; 2014 Jul; 289(27):18693-706. PubMed ID: 24841203 [TBL] [Abstract][Full Text] [Related]
20. Epidermal growth factor receptor (EGFR) ubiquitination as a mechanism of acquired resistance escaping treatment by the anti-EGFR monoclonal antibody cetuximab. Lu Y; Li X; Liang K; Luwor R; Siddik ZH; Mills GB; Mendelsohn J; Fan Z Cancer Res; 2007 Sep; 67(17):8240-7. PubMed ID: 17804738 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]