BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 27716614)

  • 1. TNF induced cleavage of HSP90 by cathepsin D potentiates apoptotic cell death.
    Fritsch J; Fickers R; Klawitter J; Särchen V; Zingler P; Adam D; Janssen O; Krause E; Schütze S
    Oncotarget; 2016 Nov; 7(46):75774-75789. PubMed ID: 27716614
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cathepsin D links TNF-induced acid sphingomyelinase to Bid-mediated caspase-9 and -3 activation.
    Heinrich M; Neumeyer J; Jakob M; Hallas C; Tchikov V; Winoto-Morbach S; Wickel M; Schneider-Brachert W; Trauzold A; Hethke A; Schütze S
    Cell Death Differ; 2004 May; 11(5):550-63. PubMed ID: 14739942
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tumor Necrosis Factor-α Induced Apoptosis in U937 Cells Promotes Cathepsin D-Independent Stefin B Degradation.
    Bidovec K; Božič J; Dolenc I; Turk B; Turk V; Stoka V
    J Cell Biochem; 2017 Dec; 118(12):4813-4820. PubMed ID: 28543404
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Selective HSP90β inhibition results in TNF and TRAIL mediated HIF1α degradation.
    Heck AL; Mishra S; Prenzel T; Feulner L; Achhammer E; Särchen V; Blagg BSJ; Schneider-Brachert W; Schütze S; Fritsch J
    Immunobiology; 2021 Mar; 226(2):152070. PubMed ID: 33639524
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cystein cathepsin and Hsp90 activities determine the balance between apoptotic and necrotic cell death pathways in caspase-compromised U937 cells.
    Imre G; Dunai Z; Petak I; Mihalik R
    Biochim Biophys Acta; 2007 Oct; 1773(10):1546-57. PubMed ID: 17707089
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Lysosome-mediated apoptosis is associated with cathepsin D-specific processing of bid at Phe24, Trp48, and Phe183.
    Appelqvist H; Johansson AC; Linderoth E; Johansson U; Antonsson B; Steinfeld R; Kågedal K; Ollinger K
    Ann Clin Lab Sci; 2012; 42(3):231-42. PubMed ID: 22964611
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Heat shock protein 90 suppresses tumor necrosis factor alpha induced apoptosis by preventing the cleavage of Bid in NIH3T3 fibroblasts.
    Zhao C; Wang E
    Cell Signal; 2004 Mar; 16(3):313-21. PubMed ID: 14687661
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Sensitization of mesothelioma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by heat stress via the inhibition of the 3-phosphoinositide-dependent kinase 1/Akt pathway.
    Pespeni MH; Hodnett M; Abayasiriwardana KS; Roux J; Howard M; Broaddus VC; Pittet JF
    Cancer Res; 2007 Mar; 67(6):2865-71. PubMed ID: 17363610
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of heat shock protein 90 function by 17-allylamino-17-demethoxy-geldanamycin in Hodgkin's lymphoma cells down-regulates Akt kinase, dephosphorylates extracellular signal-regulated kinase, and induces cell cycle arrest and cell death.
    Georgakis GV; Li Y; Rassidakis GZ; Martinez-Valdez H; Medeiros LJ; Younes A
    Clin Cancer Res; 2006 Jan; 12(2):584-90. PubMed ID: 16428504
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Histone deacetylase inhibitors strongly sensitise neuroblastoma cells to TRAIL-induced apoptosis by a caspases-dependent increase of the pro- to anti-apoptotic proteins ratio.
    Mühlethaler-Mottet A; Flahaut M; Bourloud KB; Auderset K; Meier R; Joseph JM; Gross N
    BMC Cancer; 2006 Aug; 6():214. PubMed ID: 16930472
    [TBL] [Abstract][Full Text] [Related]  

  • 11. FADD deficiency sensitises Jurkat T cells to TNF-alpha-dependent necrosis during activation-induced cell death.
    Lawrence CP; Chow SC
    FEBS Lett; 2005 Nov; 579(28):6465-72. PubMed ID: 16289096
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Aryl hydrocarbon receptor modulation of tumor necrosis factor-alpha-induced apoptosis and lysosomal disruption in a hepatoma model that is caspase-8-independent.
    Caruso JA; Mathieu PA; Joiakim A; Zhang H; Reiners JJ
    J Biol Chem; 2006 Apr; 281(16):10954-67. PubMed ID: 16446372
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 18β-glycyrrhetinic acid potentiates Hsp90 inhibition-induced apoptosis in human epithelial ovarian carcinoma cells via activation of death receptor and mitochondrial pathway.
    Yang JC; Myung SC; Kim W; Lee CS
    Mol Cell Biochem; 2012 Nov; 370(1-2):209-19. PubMed ID: 22865487
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Signaling events triggered by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL): caspase-8 is required for TRAIL-induced apoptosis.
    Seol DW; Li J; Seol MH; Park SY; Talanian RV; Billiar TR
    Cancer Res; 2001 Feb; 61(3):1138-43. PubMed ID: 11221844
    [TBL] [Abstract][Full Text] [Related]  

  • 15. HSP90 inhibitor NVP-AUY922 enhances TRAIL-induced apoptosis by suppressing the JAK2-STAT3-Mcl-1 signal transduction pathway in colorectal cancer cells.
    Lee DH; Sung KS; Bartlett DL; Kwon YT; Lee YJ
    Cell Signal; 2015 Feb; 27(2):293-305. PubMed ID: 25446253
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Increased heat shock protein 90 (hsp90) expression leads to increased apoptosis in the monoblastoid cell line U937 following induction with TNF-alpha and cycloheximide: a possible role in immunopathology.
    Galea-Lauri J; Richardson AJ; Latchman DS; Katz DR
    J Immunol; 1996 Nov; 157(9):4109-18. PubMed ID: 8892646
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nitric oxide prevents tumor necrosis factor alpha-induced rat hepatocyte apoptosis by the interruption of mitochondrial apoptotic signaling through S-nitrosylation of caspase-8.
    Kim YM; Kim TH; Chung HT; Talanian RV; Yin XM; Billiar TR
    Hepatology; 2000 Oct; 32(4 Pt 1):770-8. PubMed ID: 11003621
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Crosstalk between extrinsic and intrinsic cell death pathways in pancreatic cancer: synergistic action of estrogen metabolite and ligands of death receptor family.
    Basu A; Castle VP; Bouziane M; Bhalla K; Haldar S
    Cancer Res; 2006 Apr; 66(8):4309-18. PubMed ID: 16618756
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Enzymatically active cathepsin D sensitizes breast carcinoma cells to TRAIL.
    Jancekova B; Ondrouskova E; Knopfova L; Smarda J; Benes P
    Tumour Biol; 2016 Aug; 37(8):10685-96. PubMed ID: 26867770
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Influence of casein kinase II in tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human rhabdomyosarcoma cells.
    Izeradjene K; Douglas L; Delaney A; Houghton JA
    Clin Cancer Res; 2004 Oct; 10(19):6650-60. PubMed ID: 15475455
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.