144 related articles for article (PubMed ID: 27718474)
1. Synthesis and evaluation of N-substituted 2-amino-4,5-diarylpyrimidines as selective adenosine A
Alachouzos G; Lenselink EB; Mulder-Krieger T; de Vries H; IJzerman AP; Louvel J
Eur J Med Chem; 2017 Jan; 125():586-602. PubMed ID: 27718474
[TBL] [Abstract][Full Text] [Related]
2. The role of 5-arylalkylamino- and 5-piperazino- moieties on the 7-aminopyrazolo[4,3-d]pyrimidine core in affecting adenosine A
Squarcialupi L; Betti M; Catarzi D; Varano F; Falsini M; Ravani A; Pasquini S; Vincenzi F; Salmaso V; Sturlese M; Varani K; Moro S; Colotta V
J Enzyme Inhib Med Chem; 2017 Dec; 32(1):248-263. PubMed ID: 28114825
[TBL] [Abstract][Full Text] [Related]
3. 7-Amino-2-phenylpyrazolo[4,3-d]pyrimidine derivatives: structural investigations at the 5-position to target human A₁ and A(2A) adenosine receptors. Molecular modeling and pharmacological studies.
Squarcialupi L; Colotta V; Catarzi D; Varano F; Betti M; Varani K; Vincenzi F; Borea PA; Porta N; Ciancetta A; Moro S
Eur J Med Chem; 2014 Sep; 84():614-27. PubMed ID: 25063944
[TBL] [Abstract][Full Text] [Related]
4. 5-Substituted 2-benzylidene-1-tetralone analogues as A
Janse van Rensburg HD; Terre'Blanche G; van der Walt MM; Legoabe LJ
Bioorg Chem; 2017 Oct; 74():251-259. PubMed ID: 28881253
[TBL] [Abstract][Full Text] [Related]
5. 2-Aminopyrimidines as dual adenosine A1/A2A antagonists.
Robinson SJ; Petzer JP; Terre'Blanche G; Petzer A; van der Walt MM; Bergh JJ; Lourens AC
Eur J Med Chem; 2015 Nov; 104():177-88. PubMed ID: 26462195
[TBL] [Abstract][Full Text] [Related]
6. Chiral pyrrolo[2,3-d]pyrimidine and pyrimido[4,5-b]indole derivatives: structure-activity relationships of potent, highly stereoselective A1-adenosine receptor antagonists.
Müller CE; Geis U; Grahner B; Lanzner W; Eger K
J Med Chem; 1996 Jun; 39(13):2482-91. PubMed ID: 8691445
[TBL] [Abstract][Full Text] [Related]
7. Design, synthesis, and biological evaluation of C9- and C2-substituted pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines as new A2A and A3 adenosine receptors antagonists.
Baraldi PG; Fruttarolo F; Tabrizi MA; Preti D; Romagnoli R; El-Kashef H; Moorman A; Varani K; Gessi S; Merighi S; Borea PA
J Med Chem; 2003 Mar; 46(7):1229-41. PubMed ID: 12646033
[TBL] [Abstract][Full Text] [Related]
8. Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives: potent and selective A(2A) adenosine antagonists.
Baraldi PG; Cacciari B; Spalluto G; Pineda de las Infantas y Villatoro MJ; Zocchi C; Dionisotti S; Ongini E
J Med Chem; 1996 Mar; 39(5):1164-71. PubMed ID: 8676354
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and evaluation of methoxy substituted 2-benzoyl-1-benzofuran derivatives as lead compounds for the development adenosine A
Janse van Rensburg HD; Legoabe LJ; Terre'Blanche G; Aucamp J
Bioorg Chem; 2020 Jan; 94():103459. PubMed ID: 31818481
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and pharmacology of pyrido[2,3-d]pyrimidinediones bearing polar substituents as adenosine receptor antagonists.
Bulicz J; Bertarelli DC; Baumert D; Fülle F; Müller CE; Heber D
Bioorg Med Chem; 2006 Apr; 14(8):2837-49. PubMed ID: 16377196
[TBL] [Abstract][Full Text] [Related]
11. Imidazo[1,2-α]pyridines possess adenosine A
Lefin R; van der Walt MM; Milne PJ; Terre'Blanche G
Bioorg Med Chem Lett; 2017 Sep; 27(17):3963-3967. PubMed ID: 28789895
[TBL] [Abstract][Full Text] [Related]
12. Pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as selective human A(1) adenosine receptor ligands.
Giovannoni MP; Vergelli C; Cilibrizzi A; Crocetti L; Biancalani C; Graziano A; Dal Piaz V; Loza MI; Cadavid MI; Díaz JL; Gavaldà A
Bioorg Med Chem; 2010 Nov; 18(22):7890-9. PubMed ID: 20937560
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and structure-activity relationship of pyrazolo[3,4-d]pyrimidines: potent and selective adenosine A1 receptor antagonists.
Poulsen SA; Quinn RJ
J Med Chem; 1996 Oct; 39(21):4156-61. PubMed ID: 8863792
[TBL] [Abstract][Full Text] [Related]
14. C2-substituted quinazolinone derivatives exhibit A
Pieterse L; van der Walt MM; Terre'Blanche G
Bioorg Med Chem Lett; 2020 Aug; 30(16):127274. PubMed ID: 32631506
[TBL] [Abstract][Full Text] [Related]
15. 7-Substituted 5-amino-2-(2-furyl)pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines as A2A adenosine receptor antagonists: a study on the importance of modifications at the side chain on the activity and solubility.
Baraldi PG; Cacciari B; Romagnoli R; Spalluto G; Monopoli A; Ongini E; Varani K; Borea PA
J Med Chem; 2002 Jan; 45(1):115-26. PubMed ID: 11754583
[TBL] [Abstract][Full Text] [Related]
16. 1,3,7-Triethyl-substituted xanthines--possess nanomolar affinity for the adenosine A1 receptor.
Van der Walt MM; Terre'Blanche G
Bioorg Med Chem; 2015 Oct; 23(20):6641-9. PubMed ID: 26392370
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and Structure Activity Relationships of Chalcone based Benzocycloalkanone Derivatives as Adenosine A1 and/or A2A Receptor Antagonists.
Janse van Rensburg HD; Legoabe LJ; Terre'Blanche G
Drug Res (Stuttg); 2020 Jun; 70(6):243-256. PubMed ID: 32349128
[TBL] [Abstract][Full Text] [Related]
18. Discovery of 1,3-diethyl-7-methyl-8-(phenoxymethyl)-xanthine derivatives as novel adenosine A
Harmse R; van der Walt MM; Petzer JP; Terre'Blanche G
Bioorg Med Chem Lett; 2016 Dec; 26(24):5951-5955. PubMed ID: 27836398
[TBL] [Abstract][Full Text] [Related]
19. The significance of 2-furyl ring substitution with a 2-(para-substituted) aryl group in a new series of pyrazolo-triazolo-pyrimidines as potent and highly selective hA(3) adenosine receptors antagonists: new insights into structure-affinity relationship and receptor-antagonist recognition.
Cheong SL; Dolzhenko A; Kachler S; Paoletta S; Federico S; Cacciari B; Dolzhenko A; Klotz KN; Moro S; Spalluto G; Pastorin G
J Med Chem; 2010 Apr; 53(8):3361-75. PubMed ID: 20307065
[TBL] [Abstract][Full Text] [Related]
20. [1,2,4]Triazolo[1,5-c]pyrimidines as adenosine receptor antagonists: Modifications at the 8 position to reach selectivity towards A
Federico S; Margiotta E; Salmaso V; Pastorin G; Kachler S; Klotz KN; Moro S; Spalluto G
Eur J Med Chem; 2018 Sep; 157():837-851. PubMed ID: 30144700
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
