BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

292 related articles for article (PubMed ID: 27721407)

  • 1. HDAC1 and HDAC2 integrate the expression of p53 mutants in pancreatic cancer.
    Stojanovic N; Hassan Z; Wirth M; Wenzel P; Beyer M; Schäfer C; Brand P; Kroemer A; Stauber RH; Schmid RM; Arlt A; Sellmer A; Mahboobi S; Rad R; Reichert M; Saur D; Krämer OH; Schneider G
    Oncogene; 2017 Mar; 36(13):1804-1815. PubMed ID: 27721407
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dosage-dependent tumor suppression by histone deacetylases 1 and 2 through regulation of c-Myc collaborating genes and p53 function.
    Heideman MR; Wilting RH; Yanover E; Velds A; de Jong J; Kerkhoven RM; Jacobs H; Wessels LF; Dannenberg JH
    Blood; 2013 Mar; 121(11):2038-50. PubMed ID: 23327920
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Recruitment of histone deacetylases HDAC1 and HDAC2 by the transcriptional repressor ZEB1 downregulates E-cadherin expression in pancreatic cancer.
    Aghdassi A; Sendler M; Guenther A; Mayerle J; Behn CO; Heidecke CD; Friess H; Büchler M; Evert M; Lerch MM; Weiss FU
    Gut; 2012 Mar; 61(3):439-48. PubMed ID: 22147512
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis.
    Winter M; Moser MA; Meunier D; Fischer C; Machat G; Mattes K; Lichtenberger BM; Brunmeir R; Weissmann S; Murko C; Humer C; Meischel T; Brosch G; Matthias P; Sibilia M; Seiser C
    EMBO J; 2013 Dec; 32(24):3176-91. PubMed ID: 24240174
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Gender-dependent histone deacetylases injury may contribute to differences in liver recovery rates of male and female mice.
    Wang Y; Ye F; Ke Q; Wu Q; Yang R; Bu H
    Transplant Proc; 2013 Mar; 45(2):463-73. PubMed ID: 23498780
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Selective inhibition of histone deacetylase 2 induces p53-dependent survivin downregulation through MDM2 proteasomal degradation.
    Seo SK; Hwang CS; Choe TB; Hong SI; Yi JY; Hwang SG; Lee HG; Oh ST; Lee YH; Park IC
    Oncotarget; 2015 Sep; 6(28):26528-40. PubMed ID: 25605253
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Selective Inhibition of HDAC1 and HDAC2 as a Potential Therapeutic Option for B-ALL.
    Stubbs MC; Kim W; Bariteau M; Davis T; Vempati S; Minehart J; Witkin M; Qi J; Krivtsov AV; Bradner JE; Kung AL; Armstrong SA
    Clin Cancer Res; 2015 May; 21(10):2348-58. PubMed ID: 25688158
    [TBL] [Abstract][Full Text] [Related]  

  • 8. HDAC1 and HDAC2 collectively regulate intestinal stem cell homeostasis.
    Zimberlin CD; Lancini C; Sno R; Rosekrans SL; McLean CM; Vlaming H; van den Brink GR; Bots M; Medema JP; Dannenberg JH
    FASEB J; 2015 May; 29(5):2070-80. PubMed ID: 25648995
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Histone deacetylase 1 plays a predominant pro-oncogenic role in Eμ-myc driven B cell lymphoma.
    Pillonel V; Reichert N; Cao C; Heideman MR; Yamaguchi T; Matthias G; Tzankov A; Matthias P
    Sci Rep; 2016 Nov; 6():37772. PubMed ID: 27886239
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A toolbox for class I HDACs reveals isoform specific roles in gene regulation and protein acetylation.
    Hess L; Moos V; Lauber AA; Reiter W; Schuster M; Hartl N; Lackner D; Boenke T; Koren A; Guzzardo PM; Gundacker B; Riegler A; Vician P; Miccolo C; Leiter S; Chandrasekharan MB; Vcelkova T; Tanzer A; Jun JQ; Bradner J; Brosch G; Hartl M; Bock C; Bürckstümmer T; Kubicek S; Chiocca S; Bhaskara S; Seiser C
    PLoS Genet; 2022 Aug; 18(8):e1010376. PubMed ID: 35994477
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A dual role for Hdac1: oncosuppressor in tumorigenesis, oncogene in tumor maintenance.
    Santoro F; Botrugno OA; Dal Zuffo R; Pallavicini I; Matthews GM; Cluse L; Barozzi I; Senese S; Fornasari L; Moretti S; Altucci L; Pelicci PG; Chiocca S; Johnstone RW; Minucci S
    Blood; 2013 Apr; 121(17):3459-68. PubMed ID: 23440245
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Distinct and redundant functions of histone deacetylases HDAC1 and HDAC2 in proliferation and tumorigenesis.
    Jurkin J; Zupkovitz G; Lagger S; Grausenburger R; Hagelkruys A; Kenner L; Seiser C
    Cell Cycle; 2011 Feb; 10(3):406-12. PubMed ID: 21270520
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Overlapping functions of Hdac1 and Hdac2 in cell cycle regulation and haematopoiesis.
    Wilting RH; Yanover E; Heideman MR; Jacobs H; Horner J; van der Torre J; DePinho RA; Dannenberg JH
    EMBO J; 2010 Aug; 29(15):2586-97. PubMed ID: 20571512
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The histone deacetylases HDAC1 and HDAC2 are required for the growth and survival of renal carcinoma cells.
    Kiweler N; Brill B; Wirth M; Breuksch I; Laguna T; Dietrich C; Strand S; Schneider G; Groner B; Butter F; Heinzel T; Brenner W; Krämer OH
    Arch Toxicol; 2018 Jul; 92(7):2227-2243. PubMed ID: 29845424
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The acetylome regulators Hdac1 and Hdac2 differently modulate intestinal epithelial cell dependent homeostatic responses in experimental colitis.
    Turgeon N; Gagné JM; Blais M; Gendron FP; Boudreau F; Asselin C
    Am J Physiol Gastrointest Liver Physiol; 2014 Apr; 306(7):G594-605. PubMed ID: 24525021
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Podocyte histone deacetylase activity regulates murine and human glomerular diseases.
    Inoue K; Gan G; Ciarleglio M; Zhang Y; Tian X; Pedigo CE; Cavanaugh C; Tate J; Wang Y; Cross E; Groener M; Chai N; Wang Z; Justice A; Zhang Z; Parikh CR; Wilson FP; Ishibe S
    J Clin Invest; 2019 Mar; 129(3):1295-1313. PubMed ID: 30776024
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Wogonin has multiple anti-cancer effects by regulating c-Myc/SKP2/Fbw7α and HDAC1/HDAC2 pathways and inducing apoptosis in human lung adenocarcinoma cell line A549.
    Chen XM; Bai Y; Zhong YJ; Xie XL; Long HW; Yang YY; Wu SG; Jia Q; Wang XH
    PLoS One; 2013; 8(11):e79201. PubMed ID: 24265759
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of Class I Histone Deacetylases 1 and 2 Promotes Urothelial Carcinoma Cell Death by Various Mechanisms.
    Pinkerneil M; Hoffmann MJ; Deenen R; Köhrer K; Arent T; Schulz WA; Niegisch G
    Mol Cancer Ther; 2016 Feb; 15(2):299-312. PubMed ID: 26772204
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Histone deacetylase 1 and 2 regulate Wnt and p53 pathways in the ureteric bud epithelium.
    Chen S; Yao X; Li Y; Saifudeen Z; Bachvarov D; El-Dahr SS
    Development; 2015 Mar; 142(6):1180-92. PubMed ID: 25758227
    [TBL] [Abstract][Full Text] [Related]  

  • 20. HDAC inhibition activates the apoptosome via Apaf1 upregulation in hepatocellular carcinoma.
    Buurman R; Sandbothe M; Schlegelberger B; Skawran B
    Eur J Med Res; 2016 Jun; 21(1):26. PubMed ID: 27342975
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.