BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

313 related articles for article (PubMed ID: 27722534)

  • 21. o-Benzenedisulfonimido-sulfonamides are potent inhibitors of the tumor-associated carbonic anhydrase isoforms CA IX and CA XII.
    Güzel-Akdemir Ö; Akdemir A; Isik S; Vullo D; Supuran CT
    Bioorg Med Chem; 2013 Mar; 21(6):1386-91. PubMed ID: 23352754
    [TBL] [Abstract][Full Text] [Related]  

  • 22. New superacid synthesized (fluorinated) tertiary benzenesulfonamides acting as selective hCA IX inhibitors: toward a new mode of carbonic anhydrase inhibition by sulfonamides.
    Métayer B; Mingot A; Vullo D; Supuran CT; Thibaudeau S
    Chem Commun (Camb); 2013 Jul; 49(54):6015-7. PubMed ID: 23503420
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Privileged scaffolds in medicinal chemistry: Studies on pyrazolo[1,5-a]pyrimidines on sulfonamide containing Carbonic Anhydrase inhibitors.
    Gumus A; Bozdag M; Angeli A; Peat TS; Carta F; Supuran CT; Selleri S
    Bioorg Med Chem Lett; 2021 Oct; 49():128309. PubMed ID: 34371130
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II "selective" inhibitor celecoxib.
    Di Fiore A; Pedone C; D'Ambrosio K; Scozzafava A; De Simone G; Supuran CT
    Bioorg Med Chem Lett; 2006 Jan; 16(2):437-42. PubMed ID: 16290146
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Dissecting the inhibition mechanism of cytosolic versus transmembrane carbonic anhydrases by ESR.
    Ciani L; Cecchi A; Temperini C; Supuran CT; Ristori S
    J Phys Chem B; 2009 Oct; 113(42):13998-4005. PubMed ID: 19778001
    [TBL] [Abstract][Full Text] [Related]  

  • 26. A Combined Crystallographic and Theoretical Study Explains the Capability of Carboxylic Acids to Adopt Multiple Binding Modes in the Active Site of Carbonic Anhydrases.
    Langella E; D'Ambrosio K; D'Ascenzio M; Carradori S; Monti SM; Supuran CT; De Simone G
    Chemistry; 2016 Jan; 22(1):97-100. PubMed ID: 26507456
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Design of two-tail compounds with rotationally fixed benzenesulfonamide ring as inhibitors of carbonic anhydrases.
    Zakšauskas A; Čapkauskaitė E; Jezepčikas L; Linkuvienė V; Kišonaitė M; Smirnov A; Manakova E; Gražulis S; Matulis D
    Eur J Med Chem; 2018 Aug; 156():61-78. PubMed ID: 30006175
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Benzimidazole design, synthesis, and docking to build selective carbonic anhydrase VA inhibitors.
    Čapkauskaitė E; Zakšauskas A; Ruibys V; Linkuvienė V; Paketurytė V; Gedgaudas M; Kairys V; Matulis D
    Bioorg Med Chem; 2018 Feb; 26(3):675-687. PubMed ID: 29305297
    [TBL] [Abstract][Full Text] [Related]  

  • 29. 4-Substituted-2,3,5,6-tetrafluorobenzenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, XII, and XIII.
    Dudutienė V; Zubrienė A; Smirnov A; Gylytė J; Timm D; Manakova E; Gražulis S; Matulis D
    Bioorg Med Chem; 2013 Apr; 21(7):2093-106. PubMed ID: 23394791
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Structure, function and applications of carbonic anhydrase isozymes.
    Imtaiyaz Hassan M; Shajee B; Waheed A; Ahmad F; Sly WS
    Bioorg Med Chem; 2013 Mar; 21(6):1570-82. PubMed ID: 22607884
    [TBL] [Abstract][Full Text] [Related]  

  • 31. X-ray crystallographic and kinetic investigations of 6-sulfamoyl-saccharin as a carbonic anhydrase inhibitor.
    Alterio V; Tanc M; Ivanova J; Zalubovskis R; Vozny I; Monti SM; Di Fiore A; De Simone G; Supuran CT
    Org Biomol Chem; 2015 Apr; 13(13):4064-9. PubMed ID: 25733161
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Acyl selenoureido benzensulfonamides show potent inhibitory activity against carbonic anhydrases from the pathogenic bacterium Vibrio cholerae.
    Angeli A; Abbas G; Del Prete S; Carta F; Capasso C; Supuran CT
    Bioorg Chem; 2017 Dec; 75():170-172. PubMed ID: 28957751
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Structural analysis of inhibitor binding to human carbonic anhydrase II.
    Boriack-Sjodin PA; Zeitlin S; Chen HH; Crenshaw L; Gross S; Dantanarayana A; Delgado P; May JA; Dean T; Christianson DW
    Protein Sci; 1998 Dec; 7(12):2483-9. PubMed ID: 9865942
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Carbonic anhydrase inhibitors. Sulfonamide diuretics revisited--old leads for new applications?
    Temperini C; Cecchi A; Scozzafava A; Supuran CT
    Org Biomol Chem; 2008 Jul; 6(14):2499-506. PubMed ID: 18600270
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Identification of 3,4-Dihydroisoquinoline-2(1H)-sulfonamides as potent carbonic anhydrase inhibitors: synthesis, biological evaluation, and enzyme--ligand X-ray studies.
    Gitto R; Agnello S; Ferro S; De Luca L; Vullo D; Brynda J; Mader P; Supuran CT; Chimirri A
    J Med Chem; 2010 Mar; 53(6):2401-8. PubMed ID: 20170095
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Phenylethynylbenzenesulfonamide regioisomers strongly and selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic isoforms I and II.
    Knaus EE; Innocenti A; Scozzafava A; Supuran CT
    Bioorg Med Chem Lett; 2011 Oct; 21(19):5892-6. PubMed ID: 21852133
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Exploring benzoxaborole derivatives as carbonic anhydrase inhibitors: a structural and computational analysis reveals their conformational variability as a tool to increase enzyme selectivity.
    Langella E; Alterio V; D'Ambrosio K; Cadoni R; Winum JY; Supuran CT; Monti SM; De Simone G; Di Fiore A
    J Enzyme Inhib Med Chem; 2019 Dec; 34(1):1498-1505. PubMed ID: 31423863
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Insights towards sulfonamide drug specificity in α-carbonic anhydrases.
    Aggarwal M; Kondeti B; McKenna R
    Bioorg Med Chem; 2013 Mar; 21(6):1526-33. PubMed ID: 22985956
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Synthesis of novel acridine and bis acridine sulfonamides with effective inhibitory activity against the cytosolic carbonic anhydrase isoforms II and VII.
    Ulus R; Yeşildağ I; Tanç M; Bülbül M; Kaya M; Supuran CT
    Bioorg Med Chem; 2013 Sep; 21(18):5799-805. PubMed ID: 23910989
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Characterization of human carbonic anhydrase XII stability and inhibitor binding.
    Jogaitė V; Zubrienė A; Michailovienė V; Gylytė J; Morkūnaitė V; Matulis D
    Bioorg Med Chem; 2013 Mar; 21(6):1431-6. PubMed ID: 23159038
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 16.