These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

434 related articles for article (PubMed ID: 27727187)

  • 1. Design, Synthesis and Evaluation of Novel Tacrine-Ferulic Acid Hybrids as Multifunctional Drug Candidates against Alzheimer's Disease.
    Fu Y; Mu Y; Lei H; Wang P; Li X; Leng Q; Han L; Qu X; Wang Z; Huang X
    Molecules; 2016 Oct; 21(10):. PubMed ID: 27727187
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis, pharmacology and molecular docking on multifunctional tacrine-ferulic acid hybrids as cholinesterase inhibitors against Alzheimer's disease.
    Zhu J; Yang H; Chen Y; Lin H; Li Q; Mo J; Bian Y; Pei Y; Sun H
    J Enzyme Inhib Med Chem; 2018 Dec; 33(1):496-506. PubMed ID: 29405075
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis and evaluation of novel tacrine-(β-carboline) hybrids as multifunctional agents for the treatment of Alzheimer's disease.
    Lan JS; Xie SS; Li SY; Pan LF; Wang XB; Kong LY
    Bioorg Med Chem; 2014 Nov; 22(21):6089-104. PubMed ID: 25282654
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis and biological activity of novel tacrine-isatin Schiff base hybrid derivatives.
    Riazimontazer E; Sadeghpour H; Nadri H; Sakhteman A; Tüylü Küçükkılınç T; Miri R; Edraki N
    Bioorg Chem; 2019 Aug; 89():103006. PubMed ID: 31158577
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel tacrine-grafted Ugi adducts as multipotent anti-Alzheimer drugs: a synthetic renewal in tacrine-ferulic acid hybrids.
    Benchekroun M; Bartolini M; Egea J; Romero A; Soriano E; Pudlo M; Luzet V; Andrisano V; Jimeno ML; López MG; Wehle S; Gharbi T; Refouvelet B; de Andrés L; Herrera-Arozamena C; Monti B; Bolognesi ML; Rodríguez-Franco MI; Decker M; Marco-Contelles J; Ismaili L
    ChemMedChem; 2015 Mar; 10(3):523-39. PubMed ID: 25537267
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis and evaluation of novel tacrine-coumarin hybrids as multifunctional cholinesterase inhibitors against Alzheimer's disease.
    Xie SS; Wang XB; Li JY; Yang L; Kong LY
    Eur J Med Chem; 2013 Jun; 64():540-53. PubMed ID: 23685572
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis, biological evaluation and molecular modeling study of novel tacrine-carbazole hybrids as potential multifunctional agents for the treatment of Alzheimer's disease.
    Thiratmatrakul S; Yenjai C; Waiwut P; Vajragupta O; Reubroycharoen P; Tohda M; Boonyarat C
    Eur J Med Chem; 2014 Mar; 75():21-30. PubMed ID: 24508831
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Multifunctional tacrine-flavonoid hybrids with cholinergic, β-amyloid-reducing, and metal chelating properties for the treatment of Alzheimer's disease.
    Li SY; Wang XB; Xie SS; Jiang N; Wang KD; Yao HQ; Sun HB; Kong LY
    Eur J Med Chem; 2013 Nov; 69():632-46. PubMed ID: 24095756
    [TBL] [Abstract][Full Text] [Related]  

  • 9. New tacrine-acridine hybrids as promising multifunctional drugs for potential treatment of Alzheimer's disease.
    Chufarova N; Czarnecka K; Skibiński R; Cuchra M; Majsterek I; Szymański P
    Arch Pharm (Weinheim); 2018 Jul; 351(7):e1800050. PubMed ID: 29870588
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel tacrine-8-hydroxyquinoline hybrids as multifunctional agents for the treatment of Alzheimer's disease, with neuroprotective, cholinergic, antioxidant, and copper-complexing properties.
    Fernández-Bachiller MI; Pérez C; González-Muñoz GC; Conde S; López MG; Villarroya M; García AG; Rodríguez-Franco MI
    J Med Chem; 2010 Jul; 53(13):4927-37. PubMed ID: 20545360
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and pharmacological evaluation of multifunctional tacrine derivatives against several disease pathways of AD.
    Digiacomo M; Chen Z; Wang S; Lapucci A; Macchia M; Yang X; Chu J; Han Y; Pi R; Rapposelli S
    Bioorg Med Chem Lett; 2015 Feb; 25(4):807-10. PubMed ID: 25597007
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis and pharmacological evaluation of novel tacrine-caffeic acid hybrids as multi-targeted compounds against Alzheimer's disease.
    Chao X; He X; Yang Y; Zhou X; Jin M; Liu S; Cheng Z; Liu P; Wang Y; Yu J; Tan Y; Huang Y; Qin J; Rapposelli S; Pi R
    Bioorg Med Chem Lett; 2012 Oct; 22(20):6498-502. PubMed ID: 22981331
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis, and biological evaluation of ferulic acid based 1,3,4-oxadiazole hybrids as multifunctional therapeutics for the treatment of Alzheimer's disease.
    Tripathi A; Choubey PK; Sharma P; Seth A; Saraf P; Shrivastava SK
    Bioorg Chem; 2020 Jan; 95():103506. PubMed ID: 31887472
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis and evaluation of novel tacrine-multialkoxybenzene hybrids as multi-targeted compounds against Alzheimer's disease.
    Zhang C; Du QY; Chen LD; Wu WH; Liao SY; Yu LH; Liang XT
    Eur J Med Chem; 2016 Jun; 116():200-209. PubMed ID: 27061983
    [TBL] [Abstract][Full Text] [Related]  

  • 15. O-Hydroxyl- or o-amino benzylamine-tacrine hybrids: multifunctional biometals chelators, antioxidants, and inhibitors of cholinesterase activity and amyloid-β aggregation.
    Mao F; Huang L; Luo Z; Liu A; Lu C; Xie Z; Li X
    Bioorg Med Chem; 2012 Oct; 20(19):5884-92. PubMed ID: 22944335
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis and neuroprotective evaluation of novel tacrine-benzothiazole hybrids as multi-targeted compounds against Alzheimer's disease.
    Keri RS; Quintanova C; Marques SM; Esteves AR; Cardoso SM; Santos MA
    Bioorg Med Chem; 2013 Aug; 21(15):4559-69. PubMed ID: 23768661
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis and evaluation of novel 5,6,7-trimethoxyflavone-6-chlorotacrine hybrids as potential multifunctional agents for the treatment of Alzheimer's disease.
    Liao S; Deng H; Huang S; Yang J; Wang S; Yin B; Zheng T; Zhang D; Liu J; Gao G; Ma J; Deng Z
    Bioorg Med Chem Lett; 2015 Apr; 25(7):1541-5. PubMed ID: 25724825
    [TBL] [Abstract][Full Text] [Related]  

  • 18. New racemic annulated pyrazolo[1,2-b]phthalazines as tacrine-like AChE inhibitors with potential use in Alzheimer's disease.
    Jalili-Baleh L; Nadri H; Moradi A; Bukhari SNA; Shakibaie M; Jafari M; Golshani M; Homayouni Moghadam F; Firoozpour L; Asadipour A; Emami S; Khoobi M; Foroumadi A
    Eur J Med Chem; 2017 Oct; 139():280-289. PubMed ID: 28803044
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tacrine-based Multifunctional Agents in Alzheimer's Disease: An Old Story in Continuous Development§.
    Milelli A; De Simone A; Ticchi N; Chen HH; Betari N; Andrisano V; Tumiatti V
    Curr Med Chem; 2017; 24(32):3522-3546. PubMed ID: 28294041
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Total Synthesis of Pulmonarin B and Design of Brominated Phenylacetic Acid/Tacrine Hybrids: Marine Pharmacophore Inspired Discovery of New ChE and Aβ Aggregation Inhibitors.
    Cheng ZQ; Song JL; Zhu K; Zhang J; Jiang CS; Zhang H
    Mar Drugs; 2018 Aug; 16(9):. PubMed ID: 30134630
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.