BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

348 related articles for article (PubMed ID: 27728803)

  • 1. SOX2 Is the Determining Oncogenic Switch in Promoting Lung Squamous Cell Carcinoma from Different Cells of Origin.
    Ferone G; Song JY; Sutherland KD; Bhaskaran R; Monkhorst K; Lambooij JP; Proost N; Gargiulo G; Berns A
    Cancer Cell; 2016 Oct; 30(4):519-532. PubMed ID: 27728803
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Chromosome 3q26 Gain Is an Early Event Driving Coordinated Overexpression of the PRKCI, SOX2, and ECT2 Oncogenes in Lung Squamous Cell Carcinoma.
    Liu Y; Yin N; Wang X; Khoor A; Sambandam V; Ghosh AB; Fields ZA; Murray NR; Justilien V; Fields AP
    Cell Rep; 2020 Jan; 30(3):771-782.e6. PubMed ID: 31968252
    [TBL] [Abstract][Full Text] [Related]  

  • 3. p21-activated kinase 2 binds to transcription factor SOX2 and up-regulates DEK to promote the progression of lung squamous cell carcinoma.
    Xie S; Wan X; Chen S; Hu Y; Liu X
    Lab Invest; 2022 Oct; 102(10):1109-1120. PubMed ID: 35821094
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment.
    Mollaoglu G; Jones A; Wait SJ; Mukhopadhyay A; Jeong S; Arya R; Camolotto SA; Mosbruger TL; Stubben CJ; Conley CJ; Bhutkar A; Vahrenkamp JM; Berrett KC; Cessna MH; Lane TE; Witt BL; Salama ME; Gertz J; Jones KB; Snyder EL; Oliver TG
    Immunity; 2018 Oct; 49(4):764-779.e9. PubMed ID: 30332632
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sex-Determining Region Y-box 2 Promotes Growth of Lung Squamous Cell Carcinoma and Directly Targets Cyclin D1.
    Li C; He B; Huang C; Yang H; Cao L; Huang J; Hu C
    DNA Cell Biol; 2017 Apr; 36(4):264-272. PubMed ID: 28151013
    [TBL] [Abstract][Full Text] [Related]  

  • 6. SOX2 Determines Lineage Restriction: Modeling Lung Squamous Cell Carcinoma in the Mouse.
    Murray NR; Justilien V; Fields AP
    Cancer Cell; 2016 Oct; 30(4):505-507. PubMed ID: 27728797
    [TBL] [Abstract][Full Text] [Related]  

  • 7. FGFR gene alterations in lung squamous cell carcinoma are potential targets for the multikinase inhibitor nintedanib.
    Hibi M; Kaneda H; Tanizaki J; Sakai K; Togashi Y; Terashima M; De Velasco MA; Fujita Y; Banno E; Nakamura Y; Takeda M; Ito A; Mitsudomi T; Nakagawa K; Okamoto I; Nishio K
    Cancer Sci; 2016 Nov; 107(11):1667-1676. PubMed ID: 27581340
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Sex determining region Y-Box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung.
    Yuan P; Kadara H; Behrens C; Tang X; Woods D; Solis LM; Huang J; Spinola M; Dong W; Yin G; Fujimoto J; Kim E; Xie Y; Girard L; Moran C; Hong WK; Minna JD; Wistuba II
    PLoS One; 2010 Feb; 5(2):e9112. PubMed ID: 20161759
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The PRKCI and SOX2 oncogenes are coamplified and cooperate to activate Hedgehog signaling in lung squamous cell carcinoma.
    Justilien V; Walsh MP; Ali SA; Thompson EA; Murray NR; Fields AP
    Cancer Cell; 2014 Feb; 25(2):139-51. PubMed ID: 24525231
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cancer-associated fibroblasts suppress SOX2-induced dysplasia in a lung squamous cancer coculture.
    Chen S; Giannakou A; Wyman S; Gruzas J; Golas J; Zhong W; Loreth C; Sridharan L; Yamin TT; Damelin M; Geles KG
    Proc Natl Acad Sci U S A; 2018 Dec; 115(50):E11671-E11680. PubMed ID: 30487219
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Clinical and Genetic Implications of Mutation Burden in Squamous Cell Carcinoma of the Lung.
    Okamoto T; Takada K; Sato S; Toyokawa G; Tagawa T; Shoji F; Nakanishi R; Oki E; Koike T; Nagahashi M; Ichikawa H; Shimada Y; Watanabe S; Kikuchi T; Akazawa K; Lyle S; Takabe K; Okuda S; Sugio K; Wakai T; Tsuchida M; Maehara Y
    Ann Surg Oncol; 2018 Jun; 25(6):1564-1571. PubMed ID: 29500766
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas.
    Bass AJ; Watanabe H; Mermel CH; Yu S; Perner S; Verhaak RG; Kim SY; Wardwell L; Tamayo P; Gat-Viks I; Ramos AH; Woo MS; Weir BA; Getz G; Beroukhim R; O'Kelly M; Dutt A; Rozenblatt-Rosen O; Dziunycz P; Komisarof J; Chirieac LR; Lafargue CJ; Scheble V; Wilbertz T; Ma C; Rao S; Nakagawa H; Stairs DB; Lin L; Giordano TJ; Wagner P; Minna JD; Gazdar AF; Zhu CQ; Brose MS; Cecconello I; Ribeiro U; Marie SK; Dahl O; Shivdasani RA; Tsao MS; Rubin MA; Wong KK; Regev A; Hahn WC; Beer DG; Rustgi AK; Meyerson M
    Nat Genet; 2009 Nov; 41(11):1238-42. PubMed ID: 19801978
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sox2 cooperates with Lkb1 loss in a mouse model of squamous cell lung cancer.
    Mukhopadhyay A; Berrett KC; Kc U; Clair PM; Pop SM; Carr SR; Witt BL; Oliver TG
    Cell Rep; 2014 Jul; 8(1):40-9. PubMed ID: 24953650
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of an Exosomal Long Noncoding RNA SOX2-OT in Plasma as a Promising Biomarker for Lung Squamous Cell Carcinoma.
    Teng Y; Kang H; Chu Y
    Genet Test Mol Biomarkers; 2019 Apr; 23(4):235-240. PubMed ID: 30986097
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Genomic insights into the mechanisms of FGFR1 dependency in squamous cell lung cancer.
    Mäkinen N; Meyerson M
    J Clin Invest; 2023 Nov; 133(21):. PubMed ID: 37909331
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Long noncoding RNA SOX2-OT facilitates laryngeal squamous cell carcinoma development by epigenetically inhibiting PTEN via methyltransferase EZH2.
    Tai Y; Ji Y; Liu F; Zang Y; Xu D; Ma S; Qin L; Ma J
    IUBMB Life; 2019 Sep; 71(9):1230-1239. PubMed ID: 30811870
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Prognostic significance of PIK3CA and SOX2 in Asian patients with lung squamous cell carcinoma.
    Iijima Y; Seike M; Noro R; Ibi T; Takeuchi S; Mikami I; Koizumi K; Usuda J; Gemma A
    Int J Oncol; 2015 Feb; 46(2):505-12. PubMed ID: 25384882
    [TBL] [Abstract][Full Text] [Related]  

  • 18. FGFR1 promotes the stem cell-like phenotype of FGFR1-amplified non-small cell lung cancer cells through the Hedgehog pathway.
    Ji W; Yu Y; Li Z; Wang G; Li F; Xia W; Lu S
    Oncotarget; 2016 Mar; 7(12):15118-34. PubMed ID: 26936993
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.
    Kim BR; Coyaud E; Laurent EMN; St-Germain J; Van de Laar E; Tsao MS; Raught B; Moghal N
    Mol Cell Proteomics; 2017 Oct; 16(10):1864-1888. PubMed ID: 28794006
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SOX2 suppresses CDKN1A to sustain growth of lung squamous cell carcinoma.
    Fukazawa T; Guo M; Ishida N; Yamatsuji T; Takaoka M; Yokota E; Haisa M; Miyake N; Ikeda T; Okui T; Takigawa N; Maeda Y; Naomoto Y
    Sci Rep; 2016 Feb; 6():20113. PubMed ID: 26846300
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.