210 related articles for article (PubMed ID: 27736936)
1. A High-Throughput Screening-Compatible Strategy for the Identification of Inositol Pyrophosphate Kinase Inhibitors.
Baughman BM; Wang H; An Y; Kireev D; Stashko MA; Jessen HJ; Pearce KH; Frye SV; Shears SB
PLoS One; 2016; 11(10):e0164378. PubMed ID: 27736936
[TBL] [Abstract][Full Text] [Related]
2. Use of Protein Kinase-Focused Compound Libraries for the Discovery of New Inositol Phosphate Kinase Inhibitors.
Puhl-Rubio AC; Stashko MA; Wang H; Hardy PB; Tyagi V; Li B; Wang X; Kireev D; Jessen HJ; Frye SV; Shears SB; Pearce KH
SLAS Discov; 2018 Oct; 23(9):982-988. PubMed ID: 29842835
[TBL] [Abstract][Full Text] [Related]
3. KO of 5-InsP
Gu C; Nguyen HN; Ganini D; Chen Z; Jessen HJ; Gu Z; Wang H; Shears SB
Proc Natl Acad Sci U S A; 2017 Nov; 114(45):11968-11973. PubMed ID: 29078269
[TBL] [Abstract][Full Text] [Related]
4. The Significance of the Bifunctional Kinase/Phosphatase Activities of Diphosphoinositol Pentakisphosphate Kinases (PPIP5Ks) for Coupling Inositol Pyrophosphate Cell Signaling to Cellular Phosphate Homeostasis.
Gu C; Nguyen HN; Hofer A; Jessen HJ; Dai X; Wang H; Shears SB
J Biol Chem; 2017 Mar; 292(11):4544-4555. PubMed ID: 28126903
[TBL] [Abstract][Full Text] [Related]
5. Synthetic inositol phosphate analogs reveal that PPIP5K2 has a surface-mounted substrate capture site that is a target for drug discovery.
Wang H; Godage HY; Riley AM; Weaver JD; Shears SB; Potter BV
Chem Biol; 2014 May; 21(5):689-99. PubMed ID: 24768307
[TBL] [Abstract][Full Text] [Related]
6. The kinetic properties of a human PPIP5K reveal that its kinase activities are protected against the consequences of a deteriorating cellular bioenergetic environment.
Weaver JD; Wang H; Shears SB
Biosci Rep; 2013 Feb; 33(2):e00022. PubMed ID: 23240582
[TBL] [Abstract][Full Text] [Related]
7. Characterization of a selective inhibitor of inositol hexakisphosphate kinases: use in defining biological roles and metabolic relationships of inositol pyrophosphates.
Padmanabhan U; Dollins DE; Fridy PC; York JD; Downes CP
J Biol Chem; 2009 Apr; 284(16):10571-82. PubMed ID: 19208622
[TBL] [Abstract][Full Text] [Related]
8. The significance of the 1-kinase/1-phosphatase activities of the PPIP5K family.
Shears SB; Baughman BM; Gu C; Nair VS; Wang H
Adv Biol Regul; 2017 Jan; 63():98-106. PubMed ID: 27776974
[TBL] [Abstract][Full Text] [Related]
9. Control of XPR1-dependent cellular phosphate efflux by InsP
Li X; Gu C; Hostachy S; Sahu S; Wittwer C; Jessen HJ; Fiedler D; Wang H; Shears SB
Proc Natl Acad Sci U S A; 2020 Feb; 117(7):3568-3574. PubMed ID: 32019887
[TBL] [Abstract][Full Text] [Related]
10. Protein kinase- and lipase inhibitors of inositide metabolism deplete IP
Rajasekaran SS; Illies C; Shears SB; Wang H; Ayala TS; Martins JO; Daré E; Berggren PO; Barker CJ
Cell Signal; 2018 Jan; 42():127-133. PubMed ID: 29042286
[TBL] [Abstract][Full Text] [Related]
11. A high-throughput, nonisotopic, competitive binding assay for kinases using nonselective inhibitor probes (ED-NSIP).
Vainshtein I; Silveria S; Kaul P; Rouhani R; Eglen RM; Wang J
J Biomol Screen; 2002 Dec; 7(6):507-14. PubMed ID: 14599348
[TBL] [Abstract][Full Text] [Related]
12. Inositol Pyrophosphates: Signaling Molecules with Pleiotropic Actions in Mammals.
Lee S; Kim MG; Ahn H; Kim S
Molecules; 2020 May; 25(9):. PubMed ID: 32397291
[TBL] [Abstract][Full Text] [Related]
13. Structural insight into inositol pyrophosphate turnover.
Shears SB; Weaver JD; Wang H
Adv Biol Regul; 2013 Jan; 53(1):19-27. PubMed ID: 23107997
[TBL] [Abstract][Full Text] [Related]
14. Development of a homogenous high-throughput assay for inositol hexakisphosphate kinase 1 activity.
Wormald M; Liao G; Kimos M; Barrow J; Wei H
PLoS One; 2017; 12(11):e0188852. PubMed ID: 29186181
[TBL] [Abstract][Full Text] [Related]
15. The inositol pyrophosphate metabolism of Dictyostelium discoideum does not regulate inorganic polyphosphate (polyP) synthesis.
Desfougères Y; Portela-Torres P; Qiu D; Livermore TM; Harmel RK; Borghi F; Jessen HJ; Fiedler D; Saiardi A
Adv Biol Regul; 2022 Jan; 83():100835. PubMed ID: 34782304
[TBL] [Abstract][Full Text] [Related]
16. Novel Substrates for Kinases Involved in the Biosynthesis of Inositol Pyrophosphates and Their Enhancement of ATPase Activity of a Kinase.
Mohanrao R; Manorama R; Ganguli S; Madhusudhanan MC; Bhandari R; Sureshan KM
Molecules; 2021 Jun; 26(12):. PubMed ID: 34208421
[TBL] [Abstract][Full Text] [Related]
17. A two-way switch for inositol pyrophosphate signaling: Evolutionary history and biological significance of a unique, bifunctional kinase/phosphatase.
Randall TA; Gu C; Li X; Wang H; Shears SB
Adv Biol Regul; 2020 Jan; 75():100674. PubMed ID: 31776069
[TBL] [Abstract][Full Text] [Related]
18. Two inositol hexakisphosphate kinases drive inositol pyrophosphate synthesis in plants.
Desai M; Rangarajan P; Donahue JL; Williams SP; Land ES; Mandal MK; Phillippy BQ; Perera IY; Raboy V; Gillaspy GE
Plant J; 2014 Nov; 80(4):642-53. PubMed ID: 25231822
[TBL] [Abstract][Full Text] [Related]
19. Pharmacological tools to investigate inositol polyphosphate kinases - Enzymes of increasing therapeutic relevance.
Kröber T; Bartsch SM; Fiedler D
Adv Biol Regul; 2022 Jan; 83():100836. PubMed ID: 34802993
[TBL] [Abstract][Full Text] [Related]
20. Structural analysis and detection of biological inositol pyrophosphates reveal that the family of VIP/diphosphoinositol pentakisphosphate kinases are 1/3-kinases.
Lin H; Fridy PC; Ribeiro AA; Choi JH; Barma DK; Vogel G; Falck JR; Shears SB; York JD; Mayr GW
J Biol Chem; 2009 Jan; 284(3):1863-72. PubMed ID: 18981179
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
