BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

176 related articles for article (PubMed ID: 27738314)

  • 1. Loss of UHRF2 expression is associated with human neoplasia, promoter hypermethylation, decreased 5-hydroxymethylcytosine, and high proliferative activity.
    Lu H; Bhoopatiraju S; Wang H; Schmitz NP; Wang X; Freeman MJ; Forster CL; Verneris MR; Linden MA; Hallstrom TC
    Oncotarget; 2016 Nov; 7(46):76047-76061. PubMed ID: 27738314
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Zinc Finger Protein 618 Regulates the Function of UHRF2 (Ubiquitin-like with PHD and Ring Finger Domains 2) as a Specific 5-Hydroxymethylcytosine Reader.
    Liu Y; Zhang B; Kuang H; Korakavi G; Lu LY; Yu X
    J Biol Chem; 2016 Jun; 291(26):13679-88. PubMed ID: 27129234
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Demethylation Status of Somatic DNA Extracted From Pituitary Neuroendocrine Tumors Indicates Proliferative Behavior.
    Szabó B; Németh K; Mészáros K; Szücs N; Czirják S; Reiniger L; Rajnai H; Krencz I; Karászi K; Krokker L; Patócs A; Butz H
    J Clin Endocrinol Metab; 2020 Jun; 105(6):. PubMed ID: 32232382
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The 5-Hydroxymethylcytosine (5hmC) Reader UHRF2 Is Required for Normal Levels of 5hmC in Mouse Adult Brain and Spatial Learning and Memory.
    Chen R; Zhang Q; Duan X; York P; Chen GD; Yin P; Zhu H; Xu M; Chen P; Wu Q; Li D; Samarut J; Xu G; Zhang P; Cao X; Li J; Wong J
    J Biol Chem; 2017 Mar; 292(11):4533-4543. PubMed ID: 28115522
    [TBL] [Abstract][Full Text] [Related]  

  • 5. UHRF2 commissions the completion of DNA demethylation through allosteric activation by 5hmC and K33-linked ubiquitination of XRCC1.
    Liu X; Xu B; Yang J; He L; Zhang Z; Cheng X; Yu H; Liu X; Jin T; Peng Y; Huang Y; Xia L; Wang Y; Wu J; Wu X; Liu S; Shan L; Yang X; Sun L; Liang J; Zhang Y; Shang Y
    Mol Cell; 2021 Jul; 81(14):2960-2974.e7. PubMed ID: 34111398
    [TBL] [Abstract][Full Text] [Related]  

  • 6. UHRF2 regulates local 5-methylcytosine and suppresses spontaneous seizures.
    Liu Y; Zhang B; Meng X; Korn MJ; Parent JM; Lu LY; Yu X
    Epigenetics; 2017 Jul; 12(7):551-560. PubMed ID: 28402695
    [TBL] [Abstract][Full Text] [Related]  

  • 7. UHRF2 regulates cell cycle, epigenetics and gene expression to control the timing of retinal progenitor and ganglion cell differentiation.
    Wang X; Sarver AL; Han Q; Seiler CL; Xie C; Lu H; Forster CL; Tretyakova NY; Hallstrom TC
    Development; 2022 Mar; 149(6):. PubMed ID: 35285483
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular investigation of the tandem Tudor domain and plant homeodomain histone binding domains of the epigenetic regulator UHRF2.
    Ginnard SM; Winkler AE; Mellado Fritz C; Bluhm T; Kemmer R; Gilliam M; Butkevich N; Abdrabbo S; Bricker K; Feiler J; Miller I; Zoerman J; El-Mohri Z; Khuansanguan P; Basch M; Petzold T; Kostoff M; Konopka S; Kociba B; Gillis T; Heyl DL; Trievel RC; Albaugh BN
    Proteins; 2022 Mar; 90(3):835-847. PubMed ID: 34766381
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Loss of 5hmC identifies a new type of aberrant DNA hypermethylation in glioma.
    Fernandez AF; Bayón GF; Sierra MI; Urdinguio RG; Toraño EG; García MG; Carella A; López V; Santamarina P; Pérez RF; Belmonte T; Tejedor JR; Cobo I; Menendez P; Mangas C; Ferrero C; Rodrigo L; Astudillo A; Ortea I; Cueto Díaz S; Rodríguez-Gonzalez P; García Alonso JI; Mollejo M; Meléndez B; Domínguez G; Bonilla F; Fraga MF
    Hum Mol Genet; 2018 Sep; 27(17):3046-3059. PubMed ID: 29878202
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cooperative DNA and histone binding by Uhrf2 links the two major repressive epigenetic pathways.
    Pichler G; Wolf P; Schmidt CS; Meilinger D; Schneider K; Frauer C; Fellinger K; Rottach A; Leonhardt H
    J Cell Biochem; 2011 Sep; 112(9):2585-93. PubMed ID: 21598301
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of UHRF2 as a Negative Regulator of Epithelial-Mesenchymal Transition and Its Clinical Significance in Esophageal Squamous Cell Carcinoma.
    Iguchi T; Ueda M; Masuda T; Nambara S; Kidogami S; Komatsu H; Sato K; Tobo T; Ogawa Y; Hu Q; Saito T; Hirata H; Sakimura S; Uchi R; Hayashi N; Ito S; Eguchi H; Sugimachi K; Maehara Y; Mimori K
    Oncology; 2018; 95(3):179-187. PubMed ID: 29909415
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dysregulation and prognostic potential of 5-methylcytosine (5mC), 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC) levels in prostate cancer.
    Storebjerg TM; Strand SH; Høyer S; Lynnerup AS; Borre M; Ørntoft TF; Sørensen KD
    Clin Epigenetics; 2018 Aug; 10(1):105. PubMed ID: 30086793
    [TBL] [Abstract][Full Text] [Related]  

  • 13. UHRF2 decreases H3K9ac expression by interacting with it through the PHD and SRA/YDG domain in HepG2 hepatocellular carcinoma cells.
    Zhang T; Zhao L; Zeng S; Bai L; Chen J; Zhang Z; Wang Y; Duan C
    Int J Mol Med; 2017 Jan; 39(1):126-134. PubMed ID: 28004105
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ubiquitin-like with PHD and ring finger domains 2 is a predictor of survival and a potential therapeutic target in colon cancer.
    Lu S; Yan D; Wu Z; Jiang T; Chen J; Yuan L; Lin J; Peng Z; Tang H
    Oncol Rep; 2014 Apr; 31(4):1802-10. PubMed ID: 24573556
    [TBL] [Abstract][Full Text] [Related]  

  • 15. UHRF2 mRNA expression is low in malignant glioma but silencing inhibits the growth of U251 glioma cells in vitro.
    Wu TF; Zhang W; Su ZP; Chen SS; Chen GL; Wei YX; Sun T; Xie XS; Li B; Zhou YX; Du ZW
    Asian Pac J Cancer Prev; 2012; 13(10):5137-42. PubMed ID: 23244124
    [TBL] [Abstract][Full Text] [Related]  

  • 16. UHRF1-repressed 5'-hydroxymethylcytosine is essential for the male meiotic prophase I.
    Pan H; Jiang N; Sun S; Jiang H; Xu J; Jiang X; Gao Q; Li L; Wu H; Zheng H; Qi Q; Li T; Zhang M; Zhang L; Wan X; Lin X; Wong J; Shi Q; Li R
    Cell Death Dis; 2020 Feb; 11(2):142. PubMed ID: 32081844
    [TBL] [Abstract][Full Text] [Related]  

  • 17. UV-induced activation of ATR is mediated by UHRF2.
    Hanaki S; Habara M; Shimada M
    Genes Cells; 2021 Jun; 26(6):447-454. PubMed ID: 33848395
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Profiling of oxBS-450K 5-hydroxymethylcytosine in human placenta and brain reveals enrichment at imprinted loci.
    Hernandez Mora JR; Sanchez-Delgado M; Petazzi P; Moran S; Esteller M; Iglesias-Platas I; Monk D
    Epigenetics; 2018; 13(2):182-191. PubMed ID: 28678681
    [TBL] [Abstract][Full Text] [Related]  

  • 19. E3 ligase UHRF2 stabilizes the acetyltransferase TIP60 and regulates H3K9ac and H3K14ac via RING finger domain.
    Zeng S; Wang Y; Zhang T; Bai L; Wang Y; Duan C
    Protein Cell; 2017 Mar; 8(3):202-218. PubMed ID: 27743347
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural basis for hydroxymethylcytosine recognition by the SRA domain of UHRF2.
    Zhou T; Xiong J; Wang M; Yang N; Wong J; Zhu B; Xu RM
    Mol Cell; 2014 Jun; 54(5):879-86. PubMed ID: 24813944
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.