BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

110 related articles for article (PubMed ID: 27738316)

  • 1. Mitotic arrest-induced phosphorylation of Mcl-1 revisited using two-dimensional gel electrophoresis and phosphoproteomics: nine phosphorylation sites identified.
    Chu R; Alford SE; Hart K; Kothari A; Mackintosh SG; Kovak MR; Chambers TC
    Oncotarget; 2016 Nov; 7(48):78958-78970. PubMed ID: 27738316
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CDK1 switches mitotic arrest to apoptosis by phosphorylating Bcl-2/Bax family proteins during treatment with microtubule interfering agents.
    Zhou L; Cai X; Han X; Xu N; Chang DC
    Cell Biol Int; 2014 Jun; 38(6):737-46. PubMed ID: 24677263
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Critical role of anti-apoptotic Bcl-2 protein phosphorylation in mitotic death.
    Eichhorn JM; Sakurikar N; Alford SE; Chu R; Chambers TC
    Cell Death Dis; 2013 Oct; 4(10):e834. PubMed ID: 24091677
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cdk1/cyclin B plays a key role in mitotic arrest-induced apoptosis by phosphorylation of Mcl-1, promoting its degradation and freeing Bak from sequestration.
    Chu R; Terrano DT; Chambers TC
    Biochem Pharmacol; 2012 Jan; 83(2):199-206. PubMed ID: 22024133
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 6,7-Dimethoxy-3-(3-methoxyphenyl)isoquinolin-1-amine induces mitotic arrest and apoptotic cell death through the activation of spindle assembly checkpoint in human cervical cancer cells.
    Chung KS; Choi HE; Shin JS; Cho YW; Choi JH; Cho WJ; Lee KT
    Carcinogenesis; 2013 Aug; 34(8):1852-60. PubMed ID: 23615402
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Proteomic analysis of annexin A2 phosphorylation induced by microtubule interfering agents and kinesin spindle protein inhibitors.
    Fernandez-Garcia B; Casado P; Prado MA; Ugarte-Gil LJ; Artime N; Cabal-Hierro L; Calvo E; López JA; Ramos S; Lazo PS
    J Proteome Res; 2010 Sep; 9(9):4649-60. PubMed ID: 20597553
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mcl-1 dynamics influence mitotic slippage and death in mitosis.
    Sloss O; Topham C; Diez M; Taylor S
    Oncotarget; 2016 Feb; 7(5):5176-92. PubMed ID: 26769847
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeting of tubulin polymerization and induction of mitotic blockage by Methyl 2-(5-fluoro-2-hydroxyphenyl)-1H-benzo[d]imidazole-5-carboxylate (MBIC) in human cervical cancer HeLa cell.
    Hasanpourghadi M; Karthikeyan C; Pandurangan AK; Looi CY; Trivedi P; Kobayashi K; Tanaka K; Wong WF; Mustafa MR
    J Exp Clin Cancer Res; 2016 Mar; 35():58. PubMed ID: 27030360
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cyclin-dependent kinase 1-mediated phosphorylation of YES links mitotic arrest and apoptosis during antitubulin chemotherapy.
    Wang Z; Chen X; Zhong MZ; Yang S; Zhou J; Klinkebiel DL; Karpf AR; Chen Y; Dong J
    Cell Signal; 2018 Dec; 52():137-146. PubMed ID: 30223016
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A novel BH3 mimetic efficiently induces apoptosis in melanoma cells through direct binding to anti-apoptotic Bcl-2 family proteins, including phosphorylated Mcl-1.
    Liu Y; Xie M; Song T; Sheng H; Yu X; Zhang Z
    Pigment Cell Melanoma Res; 2015 Mar; 28(2):161-70. PubMed ID: 25324174
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
    Olsen JV; Vermeulen M; Santamaria A; Kumar C; Miller ML; Jensen LJ; Gnad F; Cox J; Jensen TS; Nigg EA; Brunak S; Mann M
    Sci Signal; 2010 Jan; 3(104):ra3. PubMed ID: 20068231
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cyclin B1 overexpression induces cell death independent of mitotic arrest.
    Eichhorn JM; Kothari A; Chambers TC
    PLoS One; 2014; 9(11):e113283. PubMed ID: 25415322
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MJ-29 inhibits tubulin polymerization, induces mitotic arrest, and triggers apoptosis via cyclin-dependent kinase 1-mediated Bcl-2 phosphorylation in human leukemia U937 cells.
    Yang JS; Hour MJ; Huang WW; Lin KL; Kuo SC; Chung JG
    J Pharmacol Exp Ther; 2010 Aug; 334(2):477-88. PubMed ID: 20463006
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Chidamide Inhibits Aerobic Metabolism to Induce Pancreatic Cancer Cell Growth Arrest by Promoting Mcl-1 Degradation.
    He M; Qiao Z; Wang Y; Kuai Q; Li C; Wang Y; Jiang X; Wang X; Li W; He M; Ren S; Yu Q
    PLoS One; 2016; 11(11):e0166896. PubMed ID: 27875574
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tubulin-binding agents down-regulate matrix metalloproteinase-2 and -9 in human hormone-refractory prostate cancer cells – a critical role of Cdk1 in mitotic entry.
    Chang WL; Yu CC; Chen CS; Guh JH
    Biochem Pharmacol; 2015 Mar; 94(1):12-21. PubMed ID: 25615907
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of cyclin B1/Cdc2 in mediating Bcl-XL phosphorylation and apoptotic cell death following nocodazole-induced mitotic arrest.
    Choi HJ; Zhu BT
    Mol Carcinog; 2014 Feb; 53(2):125-37. PubMed ID: 22949227
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Alkaloids from Piper nigrum Synergistically Enhanced the Effect of Paclitaxel against Paclitaxel-Resistant Cervical Cancer Cells through the Downregulation of Mcl-1.
    Xie Z; Wei Y; Xu J; Lei J; Yu J
    J Agric Food Chem; 2019 May; 67(18):5159-5168. PubMed ID: 31006247
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Proteomic analysis of anti-cancer effects by paclitaxel treatment in cervical cancer cells.
    Lee KH; Yim EK; Kim CJ; Namkoong SE; Um SJ; Park JS
    Gynecol Oncol; 2005 Jul; 98(1):45-53. PubMed ID: 15907983
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mitotic cell death induction by targeting the mitotic spindle with tubulin-inhibitory indole derivative molecules.
    Di Cesare E; Verrico A; Miele A; Giubettini M; Rovella P; Coluccia A; Famiglini V; La Regina G; Cundari E; Silvestri R; Lavia P
    Oncotarget; 2017 Mar; 8(12):19738-19759. PubMed ID: 28160569
    [TBL] [Abstract][Full Text] [Related]  

  • 20. MCL-1 degradation mediated by JNK activation via MEKK1/TAK1-MKK4 contributes to anticancer activity of new tubulin inhibitor MT189.
    Wang W; Wang YQ; Meng T; Yi JM; Huan XJ; Ma LP; Tong LJ; Chen Y; Ding J; Shen JK; Miao ZH
    Mol Cancer Ther; 2014 Jun; 13(6):1480-91. PubMed ID: 24688049
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.