90 related articles for article (PubMed ID: 27738771)
1. The marine cytotoxin portimine is a potent and selective inducer of apoptosis.
Cuddihy SL; Drake S; Harwood DT; Selwood AI; McNabb PS; Hampton MB
Apoptosis; 2016 Dec; 21(12):1447-1452. PubMed ID: 27738771
[TBL] [Abstract][Full Text] [Related]
2. In vitro investigation of the genotoxicity of portimine, a cyclic imine toxin produced by the dinoflagellate Vulcanodinium rugosum, on human hepatic HepaRG cells.
Hogeveen K; Huet S; Besnard C; Murray JS; Harwood DT; Selwood AI; Fessard V
Toxicol In Vitro; 2021 Jun; 73():105125. PubMed ID: 33631200
[TBL] [Abstract][Full Text] [Related]
3. Antifouling activity of portimine, select semisynthetic analogues, and other microalga-derived spirocyclic imines.
Brooke DG; Cervin G; Champeau O; Harwood DT; Pavia H; Selwood AI; Svenson J; Tremblay LA; Cahill PL
Biofouling; 2018 Sep; 34(8):950-961. PubMed ID: 30539667
[TBL] [Abstract][Full Text] [Related]
4. Cyclic imine toxins survey in coastal european shellfish samples: Bioaccumulation and mode of action of 28-O-palmitoyl ester of pinnatoxin-G. first report of portimine-A bioaccumulation.
Aráoz R; Barnes P; Séchet V; Delepierre M; Zinn-Justin S; Molgó J; Zakarian A; Hess P; Servent D
Harmful Algae; 2020 Sep; 98():101887. PubMed ID: 33129465
[TBL] [Abstract][Full Text] [Related]
5. AICAR induces Bax/Bak-dependent apoptosis through upregulation of the BH3-only proteins Bim and Noxa in mouse embryonic fibroblasts.
González-Gironès DM; Moncunill-Massaguer C; Iglesias-Serret D; Cosialls AM; Pérez-Perarnau A; Palmeri CM; Rubio-Patiño C; Villunger A; Pons G; Gil J
Apoptosis; 2013 Aug; 18(8):1008-16. PubMed ID: 23605481
[TBL] [Abstract][Full Text] [Related]
6. Induction of apoptosis pathways in several cell lines following exposure to the marine algal toxin azaspiracid.
Twiner MJ; Hanagriff JC; Butler S; Madhkoor AK; Doucette GJ
Chem Res Toxicol; 2012 Jul; 25(7):1493-501. PubMed ID: 22725096
[TBL] [Abstract][Full Text] [Related]
7. Identification of Portimine B, a New Cell Permeable Spiroimine That Induces Apoptosis in Oral Squamous Cell Carcinoma.
Fribley AM; Xi Y; Makris C; Alves-de-Souza C; York R; Tomas C; Wright JLC; Strangman WK
ACS Med Chem Lett; 2019 Feb; 10(2):175-179. PubMed ID: 30783499
[TBL] [Abstract][Full Text] [Related]
8. Prometaphase arrest-dependent phosphorylation of Bcl-2 and Bim reduces the association of Bcl-2 with Bak or Bim, provoking Bak activation and mitochondrial apoptosis in nocodazole-treated Jurkat T cells.
Han CR; Jun do Y; Lee JY; Kim YH
Apoptosis; 2014 Jan; 19(1):224-40. PubMed ID: 24166139
[TBL] [Abstract][Full Text] [Related]
9. Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release.
Kandasamy K; Srinivasula SM; Alnemri ES; Thompson CB; Korsmeyer SJ; Bryant JL; Srivastava RK
Cancer Res; 2003 Apr; 63(7):1712-21. PubMed ID: 12670926
[TBL] [Abstract][Full Text] [Related]
10. The Spirocyclic Imine from a Marine Benthic Dinoflagellate, Portimine, Is a Potent Anti-Human Immunodeficiency Virus Type 1 Therapeutic Lead Compound.
Izumida M; Suga K; Ishibashi F; Kubo Y
Mar Drugs; 2019 Aug; 17(9):. PubMed ID: 31450557
[TBL] [Abstract][Full Text] [Related]
11. Bax and Bak genes are essential for maximum apoptotic response by curcumin, a polyphenolic compound and cancer chemopreventive agent derived from turmeric, Curcuma longa.
Shankar S; Srivastava RK
Carcinogenesis; 2007 Jun; 28(6):1277-86. PubMed ID: 17277231
[TBL] [Abstract][Full Text] [Related]
12. Triggering of apoptosis by Puma is determined by the threshold set by prosurvival Bcl-2 family proteins.
Callus BA; Moujallad DM; Silke J; Gerl R; Jabbour AM; Ekert PG; Vaux DL
J Mol Biol; 2008 Dec; 384(2):313-23. PubMed ID: 18835564
[TBL] [Abstract][Full Text] [Related]
13. Mechanisms of JP-8 jet fuel cell toxicity. II. Induction of necrosis in skin fibroblasts and keratinocytes and modulation of levels of Bcl-2 family members.
Rosenthal DS; Simbulan-Rosenthal CM; Liu WF; Stoica BA; Smulson ME
Toxicol Appl Pharmacol; 2001 Mar; 171(2):107-16. PubMed ID: 11222086
[TBL] [Abstract][Full Text] [Related]
14. Synthesis of portimines reveals the basis of their anti-cancer activity.
Tang J; Li W; Chiu TY; Martínez-Peña F; Luo Z; Chong CT; Wei Q; Gazaniga N; West TJ; See YY; Lairson LL; Parker CG; Baran PS
Nature; 2023 Oct; 622(7983):507-513. PubMed ID: 37730997
[TBL] [Abstract][Full Text] [Related]
15. Mcl-1 down-regulation potentiates ABT-737 lethality by cooperatively inducing Bak activation and Bax translocation.
Chen S; Dai Y; Harada H; Dent P; Grant S
Cancer Res; 2007 Jan; 67(2):782-91. PubMed ID: 17234790
[TBL] [Abstract][Full Text] [Related]
16. Cyclic imines: chemistry and mechanism of action: a review.
Otero A; Chapela MJ; Atanassova M; Vieites JM; Cabado AG
Chem Res Toxicol; 2011 Nov; 24(11):1817-29. PubMed ID: 21739960
[TBL] [Abstract][Full Text] [Related]
17. Kaempferol Activates G₂-Checkpoint of the Cell Cycle Resulting in G₂-Arrest and Mitochondria-Dependent Apoptosis in Human Acute Leukemia Jurkat T Cells.
Kim KY; Jang WY; Lee JY; Jun do Y; Ko JY; Yun YH; Kim YH
J Microbiol Biotechnol; 2016 Feb; 26(2):287-94. PubMed ID: 26699757
[TBL] [Abstract][Full Text] [Related]
18. Regulation of stress-induced nuclear protein redistribution: a new function of Bax and Bak uncoupled from Bcl-x(L).
Lindenboim L; Blacher E; Borner C; Stein R
Cell Death Differ; 2010 Feb; 17(2):346-59. PubMed ID: 19816507
[TBL] [Abstract][Full Text] [Related]
19. Phenylarsine oxide induces apoptosis in Bax- and Bak-deficient cells through upregulation of Bim.
Ni B; Ma Q; Li B; Zhao L; Liu Y; Zhu Y; Chen Q
Clin Cancer Res; 2012 Jan; 18(1):140-51. PubMed ID: 22048238
[TBL] [Abstract][Full Text] [Related]
20. DRP1-dependent apoptotic mitochondrial fission occurs independently of BAX, BAK and APAF1 to amplify cell death by BID and oxidative stress.
Oettinghaus B; D'Alonzo D; Barbieri E; Restelli LM; Savoia C; Licci M; Tolnay M; Frank S; Scorrano L
Biochim Biophys Acta; 2016 Aug; 1857(8):1267-1276. PubMed ID: 26997499
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]