These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

204 related articles for article (PubMed ID: 27742835)

  • 1. The TORC1-activated Proteins, p70S6K and GRB10, Regulate IL-4 Signaling and M2 Macrophage Polarization by Modulating Phosphorylation of Insulin Receptor Substrate-2.
    Warren KJ; Fang X; Gowda NM; Thompson JJ; Heller NM
    J Biol Chem; 2016 Nov; 291(48):24922-24930. PubMed ID: 27742835
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Suppressor of Cytokine Signaling (SOCS)1 Regulates Interleukin-4 (IL-4)-activated Insulin Receptor Substrate (IRS)-2 Tyrosine Phosphorylation in Monocytes and Macrophages via the Proteasome.
    McCormick SM; Gowda N; Fang JX; Heller NM
    J Biol Chem; 2016 Sep; 291(39):20574-87. PubMed ID: 27507812
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Amino Acids Attenuate Insulin Action on Gluconeogenesis and Promote Fatty Acid Biosynthesis via mTORC1 Signaling Pathway in trout Hepatocytes.
    Dai W; Panserat S; Plagnes-Juan E; Seiliez I; Skiba-Cassy S
    Cell Physiol Biochem; 2015; 36(3):1084-100. PubMed ID: 26112996
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Grb10/Nedd4-mediated multiubiquitination of the insulin-like growth factor receptor regulates receptor internalization.
    Monami G; Emiliozzi V; Morrione A
    J Cell Physiol; 2008 Aug; 216(2):426-37. PubMed ID: 18286479
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Alpha-synuclein overexpression negatively regulates insulin receptor substrate 1 by activating mTORC1/S6K1 signaling.
    Gao S; Duan C; Gao G; Wang X; Yang H
    Int J Biochem Cell Biol; 2015 Jul; 64():25-33. PubMed ID: 25813876
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Insulin receptor substrate-2-dependent interleukin-4 signaling in macrophages is impaired in two models of type 2 diabetes mellitus.
    Hartman ME; O'Connor JC; Godbout JP; Minor KD; Mazzocco VR; Freund GG
    J Biol Chem; 2004 Jul; 279(27):28045-50. PubMed ID: 15123681
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Carrageenan Inhibits Insulin Signaling through GRB10-mediated Decrease in Tyr(P)-IRS1 and through Inflammation-induced Increase in Ser(P)307-IRS1.
    Bhattacharyya S; Feferman L; Tobacman JK
    J Biol Chem; 2015 Apr; 290(17):10764-74. PubMed ID: 25784556
    [TBL] [Abstract][Full Text] [Related]  

  • 8. mTOR complex 2 regulates proper turnover of insulin receptor substrate-1 via the ubiquitin ligase subunit Fbw8.
    Kim SJ; DeStefano MA; Oh WJ; Wu CC; Vega-Cotto NM; Finlan M; Liu D; Su B; Jacinto E
    Mol Cell; 2012 Dec; 48(6):875-87. PubMed ID: 23142081
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Serine 302 Phosphorylation of Mouse Insulin Receptor Substrate 1 (IRS1) Is Dispensable for Normal Insulin Signaling and Feedback Regulation by Hepatic S6 Kinase.
    Copps KD; Hançer NJ; Qiu W; White MF
    J Biol Chem; 2016 Apr; 291(16):8602-17. PubMed ID: 26846849
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of amino acid transporter trafficking by mTORC1 in primary human trophoblast cells is mediated by the ubiquitin ligase Nedd4-2.
    Rosario FJ; Dimasuay KG; Kanai Y; Powell TL; Jansson T
    Clin Sci (Lond); 2016 Apr; 130(7):499-512. PubMed ID: 26608079
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of the mTOR/p70S6K pathway is not involved in the insulin-sensitizing effect of AMPK on cardiac glucose uptake.
    Ginion A; Auquier J; Benton CR; Mouton C; Vanoverschelde JL; Hue L; Horman S; Beauloye C; Bertrand L
    Am J Physiol Heart Circ Physiol; 2011 Aug; 301(2):H469-77. PubMed ID: 21602475
    [TBL] [Abstract][Full Text] [Related]  

  • 12. USP15 attenuates IGF-I signaling by antagonizing Nedd4-induced IRS-2 ubiquitination.
    Fukushima T; Yoshihara H; Furuta H; Hakuno F; Iemura SI; Natsume T; Nakatsu Y; Kamata H; Asano T; Komada M; Takahashi SI
    Biochem Biophys Res Commun; 2017 Mar; 484(3):522-528. PubMed ID: 28126338
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural basis for the interaction between the growth factor-binding protein GRB10 and the E3 ubiquitin ligase NEDD4.
    Huang Q; Szebenyi DM
    J Biol Chem; 2010 Dec; 285(53):42130-9. PubMed ID: 20980250
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin.
    Takano A; Usui I; Haruta T; Kawahara J; Uno T; Iwata M; Kobayashi M
    Mol Cell Biol; 2001 Aug; 21(15):5050-62. PubMed ID: 11438661
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Grb10 promotes lipolysis and thermogenesis by phosphorylation-dependent feedback inhibition of mTORC1.
    Liu M; Bai J; He S; Villarreal R; Hu D; Zhang C; Yang X; Liang H; Slaga TJ; Yu Y; Zhou Z; Blenis J; Scherer PE; Dong LQ; Liu F
    Cell Metab; 2014 Jun; 19(6):967-80. PubMed ID: 24746805
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Insulin and metabolic stress stimulate multisite serine/threonine phosphorylation of insulin receptor substrate 1 and inhibit tyrosine phosphorylation.
    Hançer NJ; Qiu W; Cherella C; Li Y; Copps KD; White MF
    J Biol Chem; 2014 May; 289(18):12467-84. PubMed ID: 24652289
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Role of Mammalian Target of Rapamycin (mTOR) in Insulin Signaling.
    Yoon MS
    Nutrients; 2017 Oct; 9(11):. PubMed ID: 29077002
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of insulin receptor substrate-1 by mTORC2 (mammalian target of rapamycin complex 2).
    Destefano MA; Jacinto E
    Biochem Soc Trans; 2013 Aug; 41(4):896-901. PubMed ID: 23863152
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PKCdelta and mTOR interact to regulate stress and IGF-I induced IRS-1 Ser312 phosphorylation in breast cancer cells.
    Mingo-Sion AM; Ferguson HA; Koller E; Reyland ME; Van Den Berg CL
    Breast Cancer Res Treat; 2005 Jun; 91(3):259-69. PubMed ID: 15952059
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Grb10/Nedd4 complex regulates ligand-induced ubiquitination and stability of the insulin-like growth factor I receptor.
    Vecchione A; Marchese A; Henry P; Rotin D; Morrione A
    Mol Cell Biol; 2003 May; 23(9):3363-72. PubMed ID: 12697834
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.