BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

239 related articles for article (PubMed ID: 27743086)

  • 1. BP-1T, an antiangiogenic benzophenone-thiazole pharmacophore, counteracts HIF-1 signalling through p53/MDM2-mediated HIF-1α proteasomal degradation.
    Thirusangu P; Vigneshwaran V; Prashanth T; Vijay Avin BR; Malojirao VH; Rakesh H; Khanum SA; Mahmood R; Prabhakar BT
    Angiogenesis; 2017 Feb; 20(1):55-71. PubMed ID: 27743086
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A tumoural angiogenic gateway blocker, Benzophenone-1B represses the HIF-1α nuclear translocation and its target gene activation against neoplastic progression.
    Thirusangu P; Vigneshwaran V; Ranganatha VL; Vijay Avin BR; Khanum SA; Mahmood R; Jayashree K; Prabhakar BT
    Biochem Pharmacol; 2017 Feb; 125():26-40. PubMed ID: 27838496
    [TBL] [Abstract][Full Text] [Related]  

  • 3. GDF-15 promotes angiogenesis through modulating p53/HIF-1α signaling pathway in hypoxic human umbilical vein endothelial cells.
    Song H; Yin D; Liu Z
    Mol Biol Rep; 2012 Apr; 39(4):4017-22. PubMed ID: 21773947
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Magnolol suppresses hypoxia-induced angiogenesis via inhibition of HIF-1α/VEGF signaling pathway in human bladder cancer cells.
    Chen MC; Lee CF; Huang WH; Chou TC
    Biochem Pharmacol; 2013 May; 85(9):1278-87. PubMed ID: 23416116
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Modulating the hypoxia-inducible factor signaling pathway as a therapeutic modality to regulate retinal angiogenesis.
    DeNiro M; Alsmadi O; Al-Mohanna F
    Exp Eye Res; 2009 Nov; 89(5):700-17. PubMed ID: 19580810
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular and functional evaluation of a novel HIF inhibitor, benzopyranyl 1,2,3-triazole compound.
    Park K; Lee HE; Lee SH; Lee D; Lee T; Lee YM
    Oncotarget; 2017 Jan; 8(5):7801-7813. PubMed ID: 27999195
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tanshinone IIA inhibits β-catenin/VEGF-mediated angiogenesis by targeting TGF-β1 in normoxic and HIF-1α in hypoxic microenvironments in human colorectal cancer.
    Sui H; Zhao J; Zhou L; Wen H; Deng W; Li C; Ji Q; Liu X; Feng Y; Chai N; Zhang Q; Cai J; Li Q
    Cancer Lett; 2017 Sep; 403():86-97. PubMed ID: 28602978
    [TBL] [Abstract][Full Text] [Related]  

  • 8. NNC 55-0396, a T-type Ca2+ channel inhibitor, inhibits angiogenesis via suppression of hypoxia-inducible factor-1α signal transduction.
    Kim KH; Kim D; Park JY; Jung HJ; Cho YH; Kim HK; Han J; Choi KY; Kwon HJ
    J Mol Med (Berl); 2015 May; 93(5):499-509. PubMed ID: 25471482
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cyclin-dependent kinase inhibitor, P276-00, inhibits HIF-1α and induces G2/M arrest under hypoxia in prostate cancer cells.
    Manohar SM; Padgaonkar AA; Jalota-Badhwar A; Rao SV; Joshi KS
    Prostate Cancer Prostatic Dis; 2012 Mar; 15(1):15-27. PubMed ID: 22083267
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Modeling the regulation of p53 activation by HIF-1 upon hypoxia.
    Wang P; Guan D; Zhang XP; Liu F; Wang W
    FEBS Lett; 2019 Sep; 593(18):2596-2611. PubMed ID: 31282018
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Liquiritigenin inhibits serum-induced HIF-1α and VEGF expression via the AKT/mTOR-p70S6K signalling pathway in HeLa cells.
    Xie SR; Wang Y; Liu CW; Luo K; Cai YQ
    Phytother Res; 2012 Aug; 26(8):1133-41. PubMed ID: 22170854
    [TBL] [Abstract][Full Text] [Related]  

  • 12. LDL suppresses angiogenesis through disruption of the HIF pathway via NF-κB inhibition which is reversed by the proteasome inhibitor BSc2118.
    Yao G; Zhang Q; Doeppner TR; Niu F; Li Q; Yang Y; Kuckelkorn U; Hagemann N; Li W; Hermann DM; Dai Y; Zhou W; Jin F
    Oncotarget; 2015 Oct; 6(30):30251-62. PubMed ID: 26388611
    [TBL] [Abstract][Full Text] [Related]  

  • 13. TAp73 opposes tumor angiogenesis by promoting hypoxia-inducible factor 1α degradation.
    Amelio I; Inoue S; Markert EK; Levine AJ; Knight RA; Mak TW; Melino G
    Proc Natl Acad Sci U S A; 2015 Jan; 112(1):226-31. PubMed ID: 25535359
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effect of MDM2 and vascular endothelial growth factor inhibition on tumor angiogenesis and metastasis in neuroblastoma.
    Patterson DM; Gao D; Trahan DN; Johnson BA; Ludwig A; Barbieri E; Chen Z; Diaz-Miron J; Vassilev L; Shohet JM; Kim ES
    Angiogenesis; 2011 Sep; 14(3):255-66. PubMed ID: 21484514
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Decursin promotes HIF-1α proteasomal degradation and immune responses in hypoxic tumour microenvironment.
    Ge Y; Yoon SH; Jang H; Jeong JH; Lee YM
    Phytomedicine; 2020 Nov; 78():153318. PubMed ID: 32896707
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Kruppel-like factor 2 inhibits hypoxia-inducible factor 1alpha expression and function in the endothelium.
    Kawanami D; Mahabeleshwar GH; Lin Z; Atkins GB; Hamik A; Haldar SM; Maemura K; Lamanna JC; Jain MK
    J Biol Chem; 2009 Jul; 284(31):20522-30. PubMed ID: 19491109
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Phosphatase SHP-2 Activates HIF-1α in Wounds In Vivo by Inhibition of 26S Proteasome Activity.
    Heun Y; Grundler Groterhorst K; Pogoda K; Kraemer BF; Pfeifer A; Pohl U; Mannell H
    Int J Mol Sci; 2019 Sep; 20(18):. PubMed ID: 31500245
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ras homolog gene family, member A promotes p53 degradation and vascular endothelial growth factor-dependent angiogenesis through an interaction with murine double minute 2 under hypoxic conditions.
    Ma J; Xue Y; Cui W; Li Y; Zhao Q; Ye W; Zheng J; Cheng Y; Ma Y; Li S; Han T; Miao L; Yao L; Zhang J; Liu W
    Cancer; 2012 Sep; 118(17):4105-16. PubMed ID: 22907703
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of p53 prevents diabetic cardiomyopathy by preventing early-stage apoptosis and cell senescence, reduced glycolysis, and impaired angiogenesis.
    Gu J; Wang S; Guo H; Tan Y; Liang Y; Feng A; Liu Q; Damodaran C; Zhang Z; Keller BB; Zhang C; Cai L
    Cell Death Dis; 2018 Jan; 9(2):82. PubMed ID: 29362483
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Minocycline accelerates hypoxia-inducible factor-1 alpha degradation and inhibits hypoxia-induced neovasculogenesis through prolyl hydroxylase, von Hippel-Lindau-dependent pathway.
    Li CH; Liao PL; Yang YT; Huang SH; Lin CH; Cheng YW; Kang JJ
    Arch Toxicol; 2014 Mar; 88(3):659-71. PubMed ID: 24292262
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.