166 related articles for article (PubMed ID: 27744175)
1. Poor and enantioselective bioavailability of naftopidil enantiomers is due to extensive and stereoselective metabolism in rat liver.
Liu X; Zhu L; Huang B; Huang J; Cai Y; Zhu L; Wu B; Fu X; Zhang X; Rong Y; Xiao Q; Guo J; Li A; Guo Y; Yuan M
J Pharm Biomed Anal; 2017 Jan; 132():165-172. PubMed ID: 27744175
[TBL] [Abstract][Full Text] [Related]
2. Enantiospecific determination of naftopidil by RRLC-MS/MS reveals stereoselective pharmacokinetics and tissue distributions in rats.
Liu X; Zhang X; Huang J; Rong Y; Luo C; Guo J; Zhu L; Huang B; Yuan M
J Pharm Biomed Anal; 2015 Aug; 112():147-54. PubMed ID: 25985066
[TBL] [Abstract][Full Text] [Related]
3. Pharmaceutical evaluation of naftopidil enantiomers: Rat functional assays in vitro and estrogen/androgen induced rat benign prostatic hyperplasia model in vivo.
Huang JJ; Cai Y; Yi YZ; Huang MY; Zhu L; He F; Liu XW; Huang BY; Yuan M
Eur J Pharmacol; 2016 Nov; 791():473-481. PubMed ID: 27615445
[TBL] [Abstract][Full Text] [Related]
4. Identification of human cytochrome P450 isozymes involved in the metabolism of naftopidil enantiomers in vitro.
Zhu L; Liu X; Zhu L; Zhang X; Fu X; Huang J; Yuan M
J Pharm Pharmacol; 2014 Nov; 66(11):1534-51. PubMed ID: 24944083
[TBL] [Abstract][Full Text] [Related]
5. Simultaneous stereoselective analysis of naftopidil and O-desmethyl naftopidil enantiomers in rat feces using an online column-switching high-performance liquid chromatography method.
Zhang YY; Liu XW; Zhu LJ; Yuan M
Biomed Chromatogr; 2014 Jul; 28(7):1030-5. PubMed ID: 24420149
[TBL] [Abstract][Full Text] [Related]
6. Human UDP-Glucuronosyltransferase 2B4 and 2B7 Are Responsible for Naftopidil Glucuronidation
Liu XW; Rong Y; Zhang XF; Huang JJ; Cai Y; Huang BY; Zhu L; Wu B; Hou N; Luo CF
Front Pharmacol; 2017; 8():984. PubMed ID: 29375383
[TBL] [Abstract][Full Text] [Related]
7. Stereoselective glucuronidation of carvedilol in human liver and intestinal microsomes.
Hanioka N; Tanaka S; Moriguchi Y; Narimatsu S
Pharmacology; 2012; 90(3-4):117-24. PubMed ID: 22814440
[TBL] [Abstract][Full Text] [Related]
8. [Metabolites of R, S-1-(2-methoxyphenyl)-4-[3-(naphtha-1-yl-oxy)-2-hydroxypropyl]-piperazin in rat plasma].
Li L; Zhou X; Yuan M; Zhou H; Wang DP
Yao Xue Xue Bao; 2006 Jan; 41(1):80-4. PubMed ID: 16683533
[TBL] [Abstract][Full Text] [Related]
9. Determination of naftopidil enantiomers in rat plasma using chiral solid phases and pre-column derivatization high-performance liquid chromatography.
Liu X; Zhang Y; Yuan M; Sun Y
J Chromatogr B Analyt Technol Biomed Life Sci; 2012 Oct; 907():140-5. PubMed ID: 23026227
[TBL] [Abstract][Full Text] [Related]
10. Stereoselective glucuronidation of ofloxacin in rat liver microsomes.
Okazaki O; Kurata T; Hakusui H; Tachizawa H
Drug Metab Dispos; 1991; 19(2):376-80. PubMed ID: 1676640
[TBL] [Abstract][Full Text] [Related]
11. Stereoselectivity and interaction between the glucuronidation of S-(-)- and R-(+)-propranolol in rat hepatic microsomes pretreated with different inducers.
Luan LJ; Shao Q; Zeng S
Pharmazie; 2005 Mar; 60(3):221-4. PubMed ID: 15801678
[TBL] [Abstract][Full Text] [Related]
12. [Pharmacokinetic profile of naftopidil in rats].
Yu D; Wan L; Lou Y
Yao Xue Xue Bao; 1998 May; 33(5):335-8. PubMed ID: 12016999
[TBL] [Abstract][Full Text] [Related]
13. Metabolic fate of the novel antihypertensive drug naftopidil.
Niebch G; Locher M; Peter G; Borbe HO
Arzneimittelforschung; 1991 Oct; 41(10):1027-32. PubMed ID: 1665973
[TBL] [Abstract][Full Text] [Related]
14. The role of human UDP-glucuronyltransferases on the formation of the methylenedioxymethamphetamine (ecstasy) phase II metabolites R- and S-3-methoxymethamphetamine 4-O-glucuronides.
Schwaninger AE; Meyer MR; Zapp J; Maurer HH
Drug Metab Dispos; 2009 Nov; 37(11):2212-20. PubMed ID: 19666989
[TBL] [Abstract][Full Text] [Related]
15. Stereoselective glucuronidation of formoterol by human liver microsomes.
Zhang M; Fawcett JP; Kennedy JM; Shaw JP
Br J Clin Pharmacol; 2000 Feb; 49(2):152-7. PubMed ID: 10671910
[TBL] [Abstract][Full Text] [Related]
16. Enantioselective disposition of (R,R)-formoterol, (S,S)-formoterol and their respective glucuronides in urine following single inhaled dosing and application to doping control.
Jacobson GA; Hostrup M; Narkowicz CK; Nichols DS; Walters EH
Drug Test Anal; 2019 Jul; 11(7):950-956. PubMed ID: 30865387
[TBL] [Abstract][Full Text] [Related]
17. Naftopidil enantiomers suppress androgen accumulation and induce cell apoptosis via the UDP-glucuronosyltransferase 2B15 in benign prostate hyperplasia.
Zhan H; Zhang S; Li L; Chen Z; Cai Y; Huang J; Wu D; Huang B; Wu B; Liu X
J Steroid Biochem Mol Biol; 2022 Jul; 221():106117. PubMed ID: 35504423
[TBL] [Abstract][Full Text] [Related]
18. Prominent but reverse stereoselectivity in propranolol glucuronidation by human UDP-glucuronosyltransferases 1A9 and 1A10.
Sten T; Qvisen S; Uutela P; Luukkanen L; Kostiainen R; Finel M
Drug Metab Dispos; 2006 Sep; 34(9):1488-94. PubMed ID: 16763014
[TBL] [Abstract][Full Text] [Related]
19. Insight into stereoselective disposition of enantiomers of a potent antithrombotic agent, S002-333 following administration of the racemic compound to mice.
Bhateria M; Rachumallu R; Yerrabelli S; Saxena AK; Bhatta RS
Eur J Pharm Sci; 2017 Apr; 101():107-114. PubMed ID: 28189817
[TBL] [Abstract][Full Text] [Related]
20. Stereoselective glucuronidation of carvedilol by Chinese liver microsomes.
You LY; Yu CN; Xie SG; Chen SQ; Zeng S
J Zhejiang Univ Sci B; 2007 Oct; 8(10):756-64. PubMed ID: 17910120
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]