These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

158 related articles for article (PubMed ID: 27744229)

  • 1. Effects of oxidative post-translational modifications on structural stability and self-assembly of λ6 immunoglobulin light chain.
    Zottig X; Laporte Wolwertz M; Golizeh M; Ohlund L; Sleno L; Bourgault S
    Biophys Chem; 2016 Dec; 219():59-68. PubMed ID: 27744229
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Probing the role of λ6 immunoglobulin light chain dimerization in amyloid formation.
    Wolwertz ML; Nguyen PT; Quittot N; Bourgault S
    Biochim Biophys Acta; 2016 Apr; 1864(4):409-18. PubMed ID: 26802902
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of amyloid fibril formation in the variable domain of λ6 light chain mutant Wil caused by the interaction between its unfolded state and epigallocatechin-3-O-gallate.
    Abe Y; Odawara N; Aeimhirunkailas N; Shibata H; Fujisaki N; Tachibana H; Ueda T
    Biochim Biophys Acta Gen Subj; 2018 Dec; 1862(12):2570-2578. PubMed ID: 30251653
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Heat-induced native dimerization prevents amyloid formation by variable domain from immunoglobulin light-chain REI.
    Nawata M; Tsutsumi H; Kobayashi Y; Unzai S; Mine S; Nakamura T; Uegaki K; Kamikubo H; Kataoka M; Hamada D
    FEBS J; 2017 Sep; 284(18):3114-3127. PubMed ID: 28736891
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural basis of light chain amyloidogenicity: comparison of the thermodynamic properties, fibrillogenic potential and tertiary structural features of four Vlambda6 proteins.
    Wall JS; Gupta V; Wilkerson M; Schell M; Loris R; Adams P; Solomon A; Stevens F; Dealwis C
    J Mol Recognit; 2004; 17(4):323-31. PubMed ID: 15227639
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The critical role of the constant region in thermal stability and aggregation of amyloidogenic immunoglobulin light chain.
    Klimtchuk ES; Gursky O; Patel RS; Laporte KL; Connors LH; Skinner M; Seldin DC
    Biochemistry; 2010 Nov; 49(45):9848-57. PubMed ID: 20936823
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A Conservative Point Mutation in a Dynamic Antigen-binding Loop of Human Immunoglobulin λ6 Light Chain Promotes Pathologic Amyloid Formation.
    Peterle D; Klimtchuk ES; Wales TE; Georgescauld F; Connors LH; Engen JR; Gursky O
    J Mol Biol; 2021 Dec; 433(24):167310. PubMed ID: 34678302
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Kinetic Stability of a Full-Length Antibody Light Chain Dimer Determines whether Endoproteolysis Can Release Amyloidogenic Variable Domains.
    Morgan GJ; Kelly JW
    J Mol Biol; 2016 Oct; 428(21):4280-4297. PubMed ID: 27569045
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Decreased amyloidogenicity caused by mutational modulation of surface properties of the immunoglobulin light chain BRE variable domain.
    Kobayashi Y; Tsutsumi H; Abe T; Ikeda K; Tashiro Y; Unzai S; Kamikubo H; Kataoka M; Hiroaki H; Hamada D
    Biochemistry; 2014 Aug; 53(31):5162-73. PubMed ID: 25062800
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Analysis of somatic hypermutation and antigenic selection in the clonal B cell in immunoglobulin light chain amyloidosis (AL).
    Abraham RS; Geyer SM; Ramírez-Alvarado M; Price-Troska TL; Gertz MA; Fonseca R
    J Clin Immunol; 2004 Jul; 24(4):340-53. PubMed ID: 15163890
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Immunoglobulin light chain amyloid aggregation.
    Blancas-Mejia LM; Misra P; Dick CJ; Cooper SA; Redhage KR; Bergman MR; Jordan TL; Maar K; Ramirez-Alvarado M
    Chem Commun (Camb); 2018 Sep; 54(76):10664-10674. PubMed ID: 30087961
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutations can cause light chains to be too stable or too unstable to form amyloid fibrils.
    Marin-Argany M; Güell-Bosch J; Blancas-Mejía LM; Villegas S; Ramirez-Alvarado M
    Protein Sci; 2015 Nov; 24(11):1829-40. PubMed ID: 26300552
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Heterogeneity in primary structure, post-translational modifications, and germline gene usage of nine full-length amyloidogenic kappa1 immunoglobulin light chains.
    Connors LH; Jiang Y; Budnik M; Théberge R; Prokaeva T; Bodi KL; Seldin DC; Costello CE; Skinner M
    Biochemistry; 2007 Dec; 46(49):14259-71. PubMed ID: 18004879
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mutations in specific structural regions of immunoglobulin light chains are associated with free light chain levels in patients with AL amyloidosis.
    Poshusta TL; Sikkink LA; Leung N; Clark RJ; Dispenzieri A; Ramirez-Alvarado M
    PLoS One; 2009; 4(4):e5169. PubMed ID: 19365555
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Lipid-derived aldehydes accelerate light chain amyloid and amorphous aggregation.
    Nieva J; Shafton A; Altobell LJ; Tripuraneni S; Rogel JK; Wentworth AD; Lerner RA; Wentworth P
    Biochemistry; 2008 Jul; 47(29):7695-705. PubMed ID: 18578541
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutational and genetic determinants of λ6 light chain amyloidogenesis.
    González-Andrade M; Becerril-Luján B; Sánchez-López R; Ceceña-Álvarez H; Pérez-Carreón JI; Ortiz E; Fernández-Velasco DA; del Pozo-Yauner L
    FEBS J; 2013 Dec; 280(23):6173-83. PubMed ID: 24107228
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Antibody Light-Chain Linker Is Important for Domain Stability and Amyloid Formation.
    Nokwe CN; Hora M; Zacharias M; Yagi H; John C; Reif B; Goto Y; Buchner J
    J Mol Biol; 2015 Nov; 427(22):3572-3586. PubMed ID: 26408269
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Assessment of renal response with urinary exosomes in patients with AL amyloidosis: A proof of concept.
    Ramirez-Alvarado M; Barnidge DR; Murray DL; Dispenzieri A; Marin-Argany M; Dick CJ; Cooper SA; Nasr SH; Ward CJ; Dasari S; Jiménez-Zepeda VH; Leung N
    Am J Hematol; 2017 Jun; 92(6):536-541. PubMed ID: 28295502
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Incomplete Refolding of Antibody Light Chains to Non-Native, Protease-Sensitive Conformations Leads to Aggregation: A Mechanism of Amyloidogenesis in Patients?
    Morgan GJ; Usher GA; Kelly JW
    Biochemistry; 2017 Dec; 56(50):6597-6614. PubMed ID: 29200282
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Counteracting effects of renal solutes on amyloid fibril formation by immunoglobulin light chains.
    Kim YS; Cape SP; Chi E; Raffen R; Wilkins-Stevens P; Stevens FJ; Manning MC; Randolph TW; Solomon A; Carpenter JF
    J Biol Chem; 2001 Jan; 276(2):1626-33. PubMed ID: 11050093
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.