BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

215 related articles for article (PubMed ID: 27746320)

  • 1. Alpha-synuclein aggregates are excluded from calbindin-D28k-positive neurons in dementia with Lewy bodies and a unilateral rotenone mouse model.
    Rcom-H'cheo-Gauthier AN; Davis A; Meedeniya ACB; Pountney DL
    Mol Cell Neurosci; 2016 Dec; 77():65-75. PubMed ID: 27746320
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Calcipotriol inhibits α-synuclein aggregation in SH-SY5Y neuroblastoma cells by a Calbindin-D28k-dependent mechanism.
    Rcom-H'cheo-Gauthier AN; Meedeniya AC; Pountney DL
    J Neurochem; 2017 Apr; 141(2):263-274. PubMed ID: 28164279
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Calpain-cleavage of alpha-synuclein: connecting proteolytic processing to disease-linked aggregation.
    Dufty BM; Warner LR; Hou ST; Jiang SX; Gomez-Isla T; Leenhouts KM; Oxford JT; Feany MB; Masliah E; Rohn TT
    Am J Pathol; 2007 May; 170(5):1725-38. PubMed ID: 17456777
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Heterogeneity in α-synuclein subtypes and their expression in cortical brain tissue lysates from Lewy body diseases and Alzheimer's disease.
    Vaikath NN; Erskine D; Morris CM; Majbour NK; Vekrellis K; Li JY; El-Agnaf OMA
    Neuropathol Appl Neurobiol; 2019 Oct; 45(6):597-608. PubMed ID: 30422353
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cellular milieu imparts distinct pathological α-synuclein strains in α-synucleinopathies.
    Peng C; Gathagan RJ; Covell DJ; Medellin C; Stieber A; Robinson JL; Zhang B; Pitkin RM; Olufemi MF; Luk KC; Trojanowski JQ; Lee VM
    Nature; 2018 May; 557(7706):558-563. PubMed ID: 29743672
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hippocampal neuronal cells that accumulate α-synuclein fragments are more vulnerable to Aβ oligomer toxicity via mGluR5--implications for dementia with Lewy bodies.
    Overk CR; Cartier A; Shaked G; Rockenstein E; Ubhi K; Spencer B; Price DL; Patrick C; Desplats P; Masliah E
    Mol Neurodegener; 2014 May; 9():18. PubMed ID: 24885390
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Clinical and biochemical correlates of insoluble alpha-synuclein in dementia with Lewy bodies.
    Klucken J; Ingelsson M; Shin Y; Irizarry MC; Hedley-Whyte ET; Frosch M; Growdon J; McLean P; Hyman BT
    Acta Neuropathol; 2006 Feb; 111(2):101-8. PubMed ID: 16482476
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Brain-derived exosomes from dementia with Lewy bodies propagate α-synuclein pathology.
    Ngolab J; Trinh I; Rockenstein E; Mante M; Florio J; Trejo M; Masliah D; Adame A; Masliah E; Rissman RA
    Acta Neuropathol Commun; 2017 Jun; 5(1):46. PubMed ID: 28599681
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Accumulation of beta-synuclein in cortical neurons is associated with autophagy attenuation in the brains of dementia with Lewy body patients.
    Evans T; Kok WL; Cowan K; Hefford M; Anichtchik O
    Brain Res; 2018 Feb; 1681():1-13. PubMed ID: 29278715
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Human amyloid beta and α-synuclein co-expression in neurons impair behavior and recapitulate features for Lewy body dementia in Caenorhabditis elegans.
    Huang X; Wang C; Chen L; Zhang T; Leung KL; Wong G
    Biochim Biophys Acta Mol Basis Dis; 2021 Oct; 1867(10):166203. PubMed ID: 34146705
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The role of NUB1 in α-synuclein degradation in Lewy body disease model mice.
    Tanji K; Miki Y; Maruyama A; Mori F; Mimura J; Itoh K; Kamitani T; Wakabayashi K
    Biochem Biophys Res Commun; 2016 Feb; 470(3):635-642. PubMed ID: 26797281
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lewy-like aggregation of α-synuclein reduces protein phosphatase 2A activity in vitro and in vivo.
    Wu J; Lou H; Alerte TN; Stachowski EK; Chen J; Singleton AB; Hamilton RL; Perez RG
    Neuroscience; 2012 Apr; 207():288-97. PubMed ID: 22326202
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Detection of elevated levels of soluble alpha-synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies.
    Paleologou KE; Kragh CL; Mann DM; Salem SA; Al-Shami R; Allsop D; Hassan AH; Jensen PH; El-Agnaf OM
    Brain; 2009 Apr; 132(Pt 4):1093-101. PubMed ID: 19155272
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synergistic neuroprotection by coffee components eicosanoyl-5-hydroxytryptamide and caffeine in models of Parkinson's disease and DLB.
    Yan R; Zhang J; Park HJ; Park ES; Oh S; Zheng H; Junn E; Voronkov M; Stock JB; Mouradian MM
    Proc Natl Acad Sci U S A; 2018 Dec; 115(51):E12053-E12062. PubMed ID: 30509990
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Presynaptic alpha-synuclein aggregates, not Lewy bodies, cause neurodegeneration in dementia with Lewy bodies.
    Kramer ML; Schulz-Schaeffer WJ
    J Neurosci; 2007 Feb; 27(6):1405-10. PubMed ID: 17287515
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Calcium: Alpha-Synuclein Interactions in Alpha-Synucleinopathies.
    Rcom-H'cheo-Gauthier AN; Osborne SL; Meedeniya AC; Pountney DL
    Front Neurosci; 2016; 10():570. PubMed ID: 28066161
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Function of α-synuclein and PINK1 in Lewy body dementia (Review).
    Minami A; Nakanishi A; Matsuda S; Kitagishi Y; Ogura Y
    Int J Mol Med; 2015 Jan; 35(1):3-9. PubMed ID: 25355138
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Alterations in mGluR5 expression and signaling in Lewy body disease and in transgenic models of alpha-synucleinopathy--implications for excitotoxicity.
    Price DL; Rockenstein E; Ubhi K; Phung V; MacLean-Lewis N; Askay D; Cartier A; Spencer B; Patrick C; Desplats P; Ellisman MH; Masliah E
    PLoS One; 2010 Nov; 5(11):e14020. PubMed ID: 21103359
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Longitudinal live imaging of retinal α-synuclein::GFP deposits in a transgenic mouse model of Parkinson's Disease/Dementia with Lewy Bodies.
    Price DL; Rockenstein E; Mante M; Adame A; Overk C; Spencer B; Duong-Polk KX; Bonhaus D; Lindsey J; Masliah E
    Sci Rep; 2016 Jul; 6():29523. PubMed ID: 27389831
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Neurotoxic conversion of beta-synuclein: a novel approach to generate a transgenic mouse model of synucleinopathies?
    Fujita M; Sekigawa A; Sekiyama K; Sugama S; Hashimoto M
    J Neurol; 2009 Aug; 256 Suppl 3():286-92. PubMed ID: 19711118
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.