These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

191 related articles for article (PubMed ID: 27748579)

  • 1. Molecular Mechanism for Isoform-Selective Inhibition of Acyl Protein Thioesterases 1 and 2 (APT1 and APT2).
    Won SJ; Davda D; Labby KJ; Hwang SY; Pricer R; Majmudar JD; Armacost KA; Rodriguez LA; Rodriguez CL; Chong FS; Torossian KA; Palakurthi J; Hur ES; Meagher JL; Brooks CL; Stuckey JA; Martin BR
    ACS Chem Biol; 2016 Dec; 11(12):3374-3382. PubMed ID: 27748579
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dynamic palmitoylation links cytosol-membrane shuttling of acyl-protein thioesterase-1 and acyl-protein thioesterase-2 with that of proto-oncogene H-ras product and growth-associated protein-43.
    Kong E; Peng S; Chandra G; Sarkar C; Zhang Z; Bagh MB; Mukherjee AB
    J Biol Chem; 2013 Mar; 288(13):9112-25. PubMed ID: 23396970
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of a serine hydrolase targeted by acyl-protein thioesterase inhibitors in Toxoplasma gondii.
    Kemp LE; Rusch M; Adibekian A; Bullen HE; Graindorge A; Freymond C; Rottmann M; Braun-Breton C; Baumeister S; Porfetye AT; Vetter IR; Hedberg C; Soldati-Favre D
    J Biol Chem; 2013 Sep; 288(38):27002-27018. PubMed ID: 23913689
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Protein depalmitoylases.
    Won SJ; Cheung See Kit M; Martin BR
    Crit Rev Biochem Mol Biol; 2018 Feb; 53(1):83-98. PubMed ID: 29239216
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Enzymatic protein depalmitoylation by acyl protein thioesterases.
    Lin DT; Conibear E
    Biochem Soc Trans; 2015 Apr; 43(2):193-8. PubMed ID: 25849916
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Small-molecule inhibition of APT1 affects Ras localization and signaling.
    Dekker FJ; Rocks O; Vartak N; Menninger S; Hedberg C; Balamurugan R; Wetzel S; Renner S; Gerauer M; Schölermann B; Rusch M; Kramer JW; Rauh D; Coates GW; Brunsveld L; Bastiaens PI; Waldmann H
    Nat Chem Biol; 2010 Jun; 6(6):449-56. PubMed ID: 20418879
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 2-Bromopalmitate reduces protein deacylation by inhibition of acyl-protein thioesterase enzymatic activities.
    Pedro MP; Vilcaes AA; Tomatis VM; Oliveira RG; Gomez GA; Daniotti JL
    PLoS One; 2013; 8(10):e75232. PubMed ID: 24098372
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Boron-based inhibitors of acyl protein thioesterases 1 and 2.
    Zimmermann TJ; Bürger M; Tashiro E; Kondoh Y; Martinez NE; Görmer K; Rosin-Steiner S; Shimizu T; Ozaki S; Mikoshiba K; Watanabe N; Hall D; Vetter IR; Osada H; Hedberg C; Waldmann H
    Chembiochem; 2013 Jan; 14(1):115-22. PubMed ID: 23239555
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Acyl protein thioesterase 1 and 2 (APT-1, APT-2) inhibitors palmostatin B, ML348 and ML349 have different effects on NRAS mutant melanoma cells.
    Vujic I; Sanlorenzo M; Esteve-Puig R; Vujic M; Kwong A; Tsumura A; Murphy R; Moy A; Posch C; Monshi B; Rappersberger K; Ortiz-Urda S
    Oncotarget; 2016 Feb; 7(6):7297-306. PubMed ID: 26771141
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of acyl protein thioesterases 1 and 2 as the cellular targets of the Ras-signaling modulators palmostatin B and M.
    Rusch M; Zimmermann TJ; Bürger M; Dekker FJ; Görmer K; Triola G; Brockmeyer A; Janning P; Böttcher T; Sieber SA; Vetter IR; Hedberg C; Waldmann H
    Angew Chem Int Ed Engl; 2011 Oct; 50(42):9838-42. PubMed ID: 21905186
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Development of highly potent inhibitors of the Ras-targeting human acyl protein thioesterases based on substrate similarity design.
    Hedberg C; Dekker FJ; Rusch M; Renner S; Wetzel S; Vartak N; Gerding-Reimers C; Bon RS; Bastiaens PI; Waldmann H
    Angew Chem Int Ed Engl; 2011 Oct; 50(42):9832-7. PubMed ID: 21905185
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A conserved but structurally divergent loop in acyl protein thioesterase 1 regulates its catalytic activity, ligand binding, and folded stability.
    Harris WT; Altieri I; Gieck I; Johnson RJ
    Proteins; 2024 Jun; 92(6):693-704. PubMed ID: 38179877
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hepatic palmitoyl-proteomes and acyl-protein thioesterase protein proximity networks link lipid modification and mitochondria.
    Speck SL; Bhatt DP; Zhang Q; Adak S; Yin L; Dong G; Feng C; Zhang W; Ben Major M; Wei X; Semenkovich CF
    Cell Rep; 2023 Nov; 42(11):113389. PubMed ID: 37925639
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Temporal Profiling Establishes a Dynamic S-Palmitoylation Cycle.
    Won SJ; Martin BR
    ACS Chem Biol; 2018 Jun; 13(6):1560-1568. PubMed ID: 29733200
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Palmitoylated acyl protein thioesterase APT2 deforms membranes to extract substrate acyl chains.
    Abrami L; Audagnotto M; Ho S; Marcaida MJ; Mesquita FS; Anwar MU; Sandoz PA; Fonti G; Pojer F; Dal Peraro M; van der Goot FG
    Nat Chem Biol; 2021 Apr; 17(4):438-447. PubMed ID: 33707782
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and evaluation of acyl protein thioesterase 1 (APT1) inhibitors.
    Biel M; Deck P; Giannis A; Waldmann H
    Chemistry; 2006 May; 12(15):4121-43. PubMed ID: 16528788
    [TBL] [Abstract][Full Text] [Related]  

  • 17. APT2 Inhibition Restores Scribble Localization and S-Palmitoylation in Snail-Transformed Cells.
    Hernandez JL; Davda D; Cheung See Kit M; Majmudar JD; Won SJ; Gang M; Pasupuleti SC; Choi AI; Bartkowiak CM; Martin BR
    Cell Chem Biol; 2017 Jan; 24(1):87-97. PubMed ID: 28065656
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Crystal structure of the human acyl protein thioesterase I from a single X-ray data set to 1.5 A.
    Devedjiev Y; Dauter Z; Kuznetsov SR; Jones TL; Derewenda ZS
    Structure; 2000 Nov; 8(11):1137-46. PubMed ID: 11080636
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identifying the Potential Substrates of the Depalmitoylation Enzyme Acyl-protein Thioesterase 1.
    Liu H; Yan P; Ren J; Wu C; Yuan W; Rao M; Zhang Z; Kong E
    Curr Mol Med; 2019; 19(5):364-375. PubMed ID: 30914023
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The autodepalmitoylating activity of APT maintains the spatial organization of palmitoylated membrane proteins.
    Vartak N; Papke B; Grecco HE; Rossmannek L; Waldmann H; Hedberg C; Bastiaens PI
    Biophys J; 2014 Jan; 106(1):93-105. PubMed ID: 24411241
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.