BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

142 related articles for article (PubMed ID: 27752093)

  • 1. Intramolecular hydrophobic interactions are critical mediators of STAT5 dimerization.
    Fahrenkamp D; Li J; Ernst S; Schmitz-Van de Leur H; Chatain N; Küster A; Koschmieder S; Lüscher B; Rossetti G; Müller-Newen G
    Sci Rep; 2016 Oct; 6():35454. PubMed ID: 27752093
    [TBL] [Abstract][Full Text] [Related]  

  • 2. An SH2 domain model of STAT5 in complex with phospho-peptides define "STAT5 Binding Signatures".
    Gianti E; Zauhar RJ
    J Comput Aided Mol Des; 2015 May; 29(5):451-70. PubMed ID: 25752764
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Exploring dual inhibitors for STAT1 and STAT5 receptors utilizing virtual screening and dynamics simulation validation.
    Raj U; Kumar H; Gupta S; Varadwaj PK
    J Biomol Struct Dyn; 2016 Oct; 34(10):2115-29. PubMed ID: 26471877
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Src family kinases interfere with dimerization of STAT5A through a phosphotyrosine-SH2 domain interaction.
    Fahrenkamp D; de Leur HS; Küster A; Chatain N; Müller-Newen G
    Cell Commun Signal; 2015 Feb; 13():10. PubMed ID: 25885255
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of isoform-specific dynamics in phosphorylation-dependent STAT5 dimerization by quantitative mass spectrometry and mathematical modeling.
    Boehm ME; Adlung L; Schilling M; Roth S; Klingmüller U; Lehmann WD
    J Proteome Res; 2014 Dec; 13(12):5685-94. PubMed ID: 25333863
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The STAT5b Linker Domain Mediates the Selectivity of Catechol Bisphosphates for STAT5b over STAT5a.
    Gräb J; Berg A; Blechschmidt L; Klüver B; Rubner S; Fu DY; Meiler J; Gräber M; Berg T
    ACS Chem Biol; 2019 Apr; 14(4):796-805. PubMed ID: 30835430
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Consequences of the disease-related L78R mutation for dimerization and activity of STAT3.
    Domoszlai T; Martincuks A; Fahrenkamp D; Schmitz-Van de Leur H; Küster A; Müller-Newen G
    J Cell Sci; 2014 May; 127(Pt 9):1899-910. PubMed ID: 24569879
    [TBL] [Abstract][Full Text] [Related]  

  • 8. How Intrinsic Molecular Dynamics Control Intramolecular Communication in Signal Transducers and Activators of Transcription Factor STAT5.
    Langenfeld F; Guarracino Y; Arock M; Trouvé A; Tchertanov L
    PLoS One; 2015; 10(12):e0145142. PubMed ID: 26717567
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Severe growth deficiency is associated with STAT5b mutations that disrupt protein folding and activity.
    Varco-Merth B; Feigerlová E; Shinde U; Rosenfeld RG; Hwa V; Rotwein P
    Mol Endocrinol; 2013 Jan; 27(1):150-61. PubMed ID: 23160480
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Small molecule STAT5-SH2 domain inhibitors exhibit potent antileukemia activity.
    Page BD; Khoury H; Laister RC; Fletcher S; Vellozo M; Manzoli A; Yue P; Turkson J; Minden MD; Gunning PT
    J Med Chem; 2012 Feb; 55(3):1047-55. PubMed ID: 22148584
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dual-inhibitors of STAT5 and STAT3: studies from molecular docking and molecular dynamics simulations.
    Shao S; Yu R; Yu Y; Li Y
    J Mol Model; 2014 Aug; 20(8):2399. PubMed ID: 25098340
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Src family kinases mediate cytoplasmic retention of activated STAT5 in BCR-ABL-positive cells.
    Chatain N; Ziegler P; Fahrenkamp D; Jost E; Moriggl R; Schmitz-Van de Leur H; Müller-Newen G
    Oncogene; 2013 Aug; 32(31):3587-97. PubMed ID: 22926520
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel multiplexed assay for identifying SH2 domain antagonists of STAT family proteins.
    Takakuma K; Ogo N; Uehara Y; Takahashi S; Miyoshi N; Asai A
    PLoS One; 2013; 8(8):e71646. PubMed ID: 23977103
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mammalian protein-protein interaction trap (MAPPIT) analysis of STAT5, CIS, and SOCS2 interactions with the growth hormone receptor.
    Uyttendaele I; Lemmens I; Verhee A; De Smet AS; Vandekerckhove J; Lavens D; Peelman F; Tavernier J
    Mol Endocrinol; 2007 Nov; 21(11):2821-31. PubMed ID: 17666591
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Critical Role of STAT5 transcription factor tetramerization for cytokine responses and normal immune function.
    Lin JX; Li P; Liu D; Jin HT; He J; Ata Ur Rasheed M; Rochman Y; Wang L; Cui K; Liu C; Kelsall BL; Ahmed R; Leonard WJ
    Immunity; 2012 Apr; 36(4):586-99. PubMed ID: 22520852
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An invertebrate signal transducer and activator of transcription 5 (STAT5) ortholog from the disk abalone, Haliotis discus discus: Genomic structure, early developmental expression, and immune responses to bacterial and viral stresses.
    Bathige SD; Umasuthan N; Park HC; Lee J
    Dev Comp Immunol; 2016 Mar; 56():46-56. PubMed ID: 26616564
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Src directly tyrosine-phosphorylates STAT5 on its activation site and is involved in erythropoietin-induced signaling pathway.
    Okutani Y; Kitanaka A; Tanaka T; Kamano H; Ohnishi H; Kubota Y; Ishida T; Takahara J
    Oncogene; 2001 Oct; 20(45):6643-50. PubMed ID: 11641791
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Physical and functional interactions between STAT5 and Runx transcription factors.
    Ogawa S; Satake M; Ikuta K
    J Biochem; 2008 May; 143(5):695-709. PubMed ID: 18296717
    [TBL] [Abstract][Full Text] [Related]  

  • 19. SEL120-34A is a novel CDK8 inhibitor active in AML cells with high levels of serine phosphorylation of STAT1 and STAT5 transactivation domains.
    Rzymski T; Mikula M; Żyłkiewicz E; Dreas A; Wiklik K; Gołas A; Wójcik K; Masiejczyk M; Wróbel A; Dolata I; Kitlińska A; Statkiewicz M; Kuklinska U; Goryca K; Sapała Ł; Grochowska A; Cabaj A; Szajewska-Skuta M; Gabor-Worwa E; Kucwaj K; Białas A; Radzimierski A; Combik M; Woyciechowski J; Mikulski M; Windak R; Ostrowski J; Brzózka K
    Oncotarget; 2017 May; 8(20):33779-33795. PubMed ID: 28422713
    [TBL] [Abstract][Full Text] [Related]  

  • 20. FYN expression potentiates FLT3-ITD induced STAT5 signaling in acute myeloid leukemia.
    Chougule RA; Kazi JU; Rönnstrand L
    Oncotarget; 2016 Mar; 7(9):9964-74. PubMed ID: 26848862
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.