These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

103 related articles for article (PubMed ID: 27753493)

  • 1. Rational Design of Cyclic Peptide Inhibitors of U2AF Homology Motif (UHM) Domains To Modulate Pre-mRNA Splicing.
    Jagtap PK; Garg D; Kapp TG; Will CL; Demmer O; Lührmann R; Kessler H; Sattler M
    J Med Chem; 2016 Nov; 59(22):10190-10197. PubMed ID: 27753493
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of phenothiazine derivatives as UHM-binding inhibitors of early spliceosome assembly.
    Jagtap PKA; Kubelka T; Soni K; Will CL; Garg D; Sippel C; Kapp TG; Potukuchi HK; Schorpp K; Hadian K; Kessler H; Lührmann R; Hausch F; Bach T; Sattler M
    Nat Commun; 2020 Nov; 11(1):5621. PubMed ID: 33159082
    [TBL] [Abstract][Full Text] [Related]  

  • 3. U2AF-homology motif interactions are required for alternative splicing regulation by SPF45.
    Corsini L; Bonnal S; Basquin J; Hothorn M; Scheffzek K; Valcárcel J; Sattler M
    Nat Struct Mol Biol; 2007 Jul; 14(7):620-9. PubMed ID: 17589525
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The pre-mRNA splicing and transcription factor Tat-SF1 is a functional partner of the spliceosome SF3b1 subunit via a U2AF homology motif interface.
    Loerch S; Leach JR; Horner SW; Maji D; Jenkins JL; Pulvino MJ; Kielkopf CL
    J Biol Chem; 2019 Feb; 294(8):2892-2902. PubMed ID: 30567737
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A UHM-ULM interface with unusual structural features contributes to U2AF2 and SF3B1 association for pre-mRNA splicing.
    Galardi JW; Bela VN; Jeffery N; He X; Glasser E; Loerch S; Jenkins JL; Pulvino MJ; Boutz PL; Kielkopf CL
    J Biol Chem; 2022 Aug; 298(8):102224. PubMed ID: 35780835
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Modulation of HIV-1 gene expression by binding of a ULM motif in the Rev protein to UHM-containing splicing factors.
    Pabis M; Corsini L; Vincendeau M; Tripsianes K; Gibson TJ; Brack-Werner R; Sattler M
    Nucleic Acids Res; 2019 May; 47(9):4859-4871. PubMed ID: 30892606
    [TBL] [Abstract][Full Text] [Related]  

  • 7. SPF45/RBM17-dependent, but not U2AF-dependent, splicing in a distinct subset of human short introns.
    Fukumura K; Yoshimoto R; Sperotto L; Kang HS; Hirose T; Inoue K; Sattler M; Mayeda A
    Nat Commun; 2021 Aug; 12(1):4910. PubMed ID: 34389706
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cancer-relevant splicing factor CAPERα engages the essential splicing factor SF3b155 in a specific ternary complex.
    Loerch S; Maucuer A; Manceau V; Green MR; Kielkopf CL
    J Biol Chem; 2014 Jun; 289(25):17325-37. PubMed ID: 24795046
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Profiling the Binding Activities of Peptides and Inhibitors to the U2 Auxiliary Factor Homology Motif (UHM) Domains.
    Yuan X; Howie KL; Kazemi Sabzvar M; Chinnaswamy K; Stuckey JA; Yang CY
    ACS Med Chem Lett; 2023 Apr; 14(4):450-457. PubMed ID: 37077390
    [TBL] [Abstract][Full Text] [Related]  

  • 10. SAP30BP interacts with RBM17/SPF45 to promote splicing in a subset of human short introns.
    Fukumura K; Sperotto L; Seuß S; Kang HS; Yoshimoto R; Sattler M; Mayeda A
    Cell Rep; 2023 Dec; 42(12):113534. PubMed ID: 38065098
    [TBL] [Abstract][Full Text] [Related]  

  • 11. UHM-ULM interactions in the RBM39-U2AF65 splicing-factor complex.
    Stepanyuk GA; Serrano P; Peralta E; Farr CL; Axelrod HL; Geralt M; Das D; Chiu HJ; Jaroszewski L; Deacon AM; Lesley SA; Elsliger MA; Godzik A; Wilson IA; Wüthrich K; Salomon DR; Williamson JR
    Acta Crystallogr D Struct Biol; 2016 Apr; 72(Pt 4):497-511. PubMed ID: 27050129
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Unmasking the U2AF homology motif family: a bona fide protein-protein interaction motif in disguise.
    Loerch S; Kielkopf CL
    RNA; 2016 Dec; 22(12):1795-1807. PubMed ID: 27852923
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Different requirements of the kinase and UHM domains of KIS for its nuclear localization and binding to splicing factors.
    Manceau V; Kielkopf CL; Sobel A; Maucuer A
    J Mol Biol; 2008 Sep; 381(3):748-62. PubMed ID: 18588901
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A synthetic small molecule stalls pre-mRNA splicing by promoting an early-stage U2AF2-RNA complex.
    Chatrikhi R; Feeney CF; Pulvino MJ; Alachouzos G; MacRae AJ; Falls Z; Rai S; Brennessel WW; Jenkins JL; Walter MJ; Graubert TA; Samudrala R; Jurica MS; Frontier AJ; Kielkopf CL
    Cell Chem Biol; 2021 Aug; 28(8):1145-1157.e6. PubMed ID: 33689684
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dimerization and protein binding specificity of the U2AF homology motif of the splicing factor Puf60.
    Corsini L; Hothorn M; Stier G; Rybin V; Scheffzek K; Gibson TJ; Sattler M
    J Biol Chem; 2009 Jan; 284(1):630-639. PubMed ID: 18974054
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Multiple U2AF65 binding sites within SF3b155: thermodynamic and spectroscopic characterization of protein-protein interactions among pre-mRNA splicing factors.
    Thickman KR; Swenson MC; Kabogo JM; Gryczynski Z; Kielkopf CL
    J Mol Biol; 2006 Feb; 356(3):664-83. PubMed ID: 16376933
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of a small molecule splicing inhibitor targeting UHM domains.
    Kobayashi A; Clément MJ; Craveur P; El Hage K; Salone JM; Bollot G; Pastré D; Maucuer A
    FEBS J; 2022 Feb; 289(3):682-698. PubMed ID: 34520118
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A novel protein-protein interaction in the RES (REtention and Splicing) complex.
    Tripsianes K; Friberg A; Barrandon C; Brooks M; van Tilbeurgh H; Seraphin B; Sattler M
    J Biol Chem; 2014 Oct; 289(41):28640-50. PubMed ID: 25160624
    [TBL] [Abstract][Full Text] [Related]  

  • 19. U2AF homology motifs: protein recognition in the RRM world.
    Kielkopf CL; Lücke S; Green MR
    Genes Dev; 2004 Jul; 18(13):1513-26. PubMed ID: 15231733
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Backbone assignment of the UHM domain of Puf60 free and bound to five ligands.
    Corsini L; Sattler M
    Biomol NMR Assign; 2008 Dec; 2(2):211-4. PubMed ID: 19636907
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.