619 related articles for article (PubMed ID: 27756327)
21. [Mechanism of Tibetan medicine Ershiwuwei Songshi Pills against liver injury induced by acetaminophen in mice based on Keap1/Nrf2 and TLR4/NF-κB p65 signaling pathways].
Sha YR; Luo XM; Ding Y; Yang B; Jian CF; Gong PY; Gu J; Tan R
Zhongguo Zhong Yao Za Zhi; 2022 Apr; 47(8):2049-2055. PubMed ID: 35531720
[TBL] [Abstract][Full Text] [Related]
22. The Keap1/Nrf2-ARE Pathway as a Pharmacological Target for Chalcones.
de Freitas Silva M; Pruccoli L; Morroni F; Sita G; Seghetti F; Viegas C; Tarozzi A
Molecules; 2018 Jul; 23(7):. PubMed ID: 30037040
[TBL] [Abstract][Full Text] [Related]
23. Induction of apoptosis by esculetin in human leukemia U937 cells through activation of JNK and ERK.
Park C; Jin CY; Kim GY; Choi IW; Kwon TK; Choi BT; Lee SJ; Lee WH; Choi YH
Toxicol Appl Pharmacol; 2008 Mar; 227(2):219-28. PubMed ID: 18031783
[TBL] [Abstract][Full Text] [Related]
24. Effects of deficiency of Kelch-like ECH-associated protein 1 on skeletal organization: a mechanism for diminished nuclear factor of activated T cells cytoplasmic 1 during osteoclastogenesis.
Sakai E; Morita M; Ohuchi M; Kido MA; Fukuma Y; Nishishita K; Okamoto K; Itoh K; Yamamoto M; Tsukuba T
FASEB J; 2017 Sep; 31(9):4011-4022. PubMed ID: 28515152
[TBL] [Abstract][Full Text] [Related]
25. Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction with High Cell Potency Identified by Fragment-Based Discovery.
Davies TG; Wixted WE; Coyle JE; Griffiths-Jones C; Hearn K; McMenamin R; Norton D; Rich SJ; Richardson C; Saxty G; Willems HM; Woolford AJ; Cottom JE; Kou JP; Yonchuk JG; Feldser HG; Sanchez Y; Foley JP; Bolognese BJ; Logan G; Podolin PL; Yan H; Callahan JF; Heightman TD; Kerns JK
J Med Chem; 2016 Apr; 59(8):3991-4006. PubMed ID: 27031670
[TBL] [Abstract][Full Text] [Related]
26. Nuclear factor (erythroid-derived 2)-like 2 (NRF2) drug discovery: Biochemical toolbox to develop NRF2 activators by reversible binding of Kelch-like ECH-associated protein 1 (KEAP1).
Bresciani A; Missineo A; Gallo M; Cerretani M; Fezzardi P; Tomei L; Cicero DO; Altamura S; Santoprete A; Ingenito R; Bianchi E; Pacifici R; Dominguez C; Munoz-Sanjuan I; Harper S; Toledo-Sherman L; Park LC
Arch Biochem Biophys; 2017 Oct; 631():31-41. PubMed ID: 28801166
[TBL] [Abstract][Full Text] [Related]
27. An effective strategy for increasing the radiosensitivity of Human lung Cancer cells by blocking Nrf2-dependent antioxidant responses.
Lee S; Lim MJ; Kim MH; Yu CH; Yun YS; Ahn J; Song JY
Free Radic Biol Med; 2012 Aug; 53(4):807-16. PubMed ID: 22684019
[TBL] [Abstract][Full Text] [Related]
28. A Novel Nrf2 Pathway Inhibitor Sensitizes Keap1-Mutant Lung Cancer Cells to Chemotherapy.
Zhang D; Hou Z; Aldrich KE; Lockwood L; Odom AL; Liby KT
Mol Cancer Ther; 2021 Sep; 20(9):1692-1701. PubMed ID: 34158350
[TBL] [Abstract][Full Text] [Related]
29. Punicalagin attenuates palmitate-induced lipotoxicity in HepG2 cells by activating the Keap1-Nrf2 antioxidant defense system.
Yan C; Sun W; Wang X; Long J; Liu X; Feng Z; Liu J
Mol Nutr Food Res; 2016 May; 60(5):1139-49. PubMed ID: 26989875
[TBL] [Abstract][Full Text] [Related]
30. Esculetin Attenuates the Growth of Lung Cancer by Downregulating Wnt Targeted Genes and Suppressing NF-κB.
Zhu X; Gu J; Qian H
Arch Bronconeumol (Engl Ed); 2018 Mar; 54(3):128-133. PubMed ID: 29108761
[TBL] [Abstract][Full Text] [Related]
31. aPKCι promotes gallbladder cancer tumorigenesis and gemcitabine resistance by competing with Nrf2 for binding to Keap1.
Tian L; Lu Y; Yang T; Deng Z; Xu L; Yao W; Ma C; Li X; Zhang J; Liu Y; Wang J
Redox Biol; 2019 Apr; 22():101149. PubMed ID: 30822690
[TBL] [Abstract][Full Text] [Related]
32. Effects of a novel biflavonoid of Lonicera japonica flower buds on modulating apoptosis under different oxidative conditions in hepatoma cells.
Wan H; Ge L; Li J; Zhang K; Wu W; Peng S; Zou X; Zhou H; Zhou B; Zeng X
Phytomedicine; 2019 Apr; 57():282-291. PubMed ID: 30802714
[TBL] [Abstract][Full Text] [Related]
33. Nrf2-Keap1 antioxidant defense and cell survival signaling are upregulated by 17β-estradiol in homocysteine-treated dopaminergic SH-SY5Y cells.
Chen CS; Tseng YT; Hsu YY; Lo YC
Neuroendocrinology; 2013; 97(3):232-41. PubMed ID: 22948038
[TBL] [Abstract][Full Text] [Related]
34. Esculetin induces death of human colon cancer cells via the reactive oxygen species-mediated mitochondrial apoptosis pathway.
Kim AD; Han X; Piao MJ; Hewage SR; Hyun CL; Cho SJ; Hyun JW
Environ Toxicol Pharmacol; 2015 Mar; 39(2):982-9. PubMed ID: 25818986
[TBL] [Abstract][Full Text] [Related]
35. Molecular cross-talk between the NRF2/KEAP1 signaling pathway, autophagy, and apoptosis.
Stępkowski TM; Kruszewski MK
Free Radic Biol Med; 2011 May; 50(9):1186-95. PubMed ID: 21295136
[TBL] [Abstract][Full Text] [Related]
36. Liquiritin protects PC12 cells from corticosterone-induced neurotoxicity via regulation of metabolic disorders, attenuation ERK1/2-NF-κB pathway, activation Nrf2-Keap1 pathway, and inhibition mitochondrial apoptosis pathway.
Li X; Qin X; Tian J; Gao X; Wu X; Du G; Zhou Y
Food Chem Toxicol; 2020 Dec; 146():111801. PubMed ID: 33035630
[TBL] [Abstract][Full Text] [Related]
37. The antidiabetic compound 2-dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione, isolated from Averrhoa carambola L., demonstrates significant antitumor potential against human breast cancer cells.
Gao Y; Huang R; Gong Y; Park HS; Wen Q; Almosnid NM; Chippada-Venkata UD; Hosain NA; Vick E; Farone A; Altman E
Oncotarget; 2015 Sep; 6(27):24304-19. PubMed ID: 26203774
[TBL] [Abstract][Full Text] [Related]
38. KEAP1/NRF2 axis regulates H
He J; Zhang X; Lian C; Wu J; Fang Y; Ye X
Gene; 2019 Apr; 691():8-17. PubMed ID: 30594636
[TBL] [Abstract][Full Text] [Related]
39. Coumarins as Modulators of the Keap1/Nrf2/ARE Signaling Pathway.
Hassanein EHM; Sayed AM; Hussein OE; Mahmoud AM
Oxid Med Cell Longev; 2020; 2020():1675957. PubMed ID: 32377290
[TBL] [Abstract][Full Text] [Related]
40. Extract of Ginkgo biloba induces phase 2 genes through Keap1-Nrf2-ARE signaling pathway.
Liu XP; Goldring CE; Copple IM; Wang HY; Wei W; Kitteringham NR; Park BK
Life Sci; 2007 Apr; 80(17):1586-91. PubMed ID: 17316704
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
