BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

196 related articles for article (PubMed ID: 27756749)

  • 1. Phosphodiesterase 4 inhibitors have wide-ranging activity in B-cell malignancies.
    Cooney JD; Aguiar RC
    Blood; 2016 Dec; 128(25):2886-2890. PubMed ID: 27756749
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A phosphodiesterase 4B-dependent interplay between tumor cells and the microenvironment regulates angiogenesis in B-cell lymphoma.
    Suhasini AN; Wang L; Holder KN; Lin AP; Bhatnagar H; Kim SW; Moritz AW; Aguiar RCT
    Leukemia; 2016 Mar; 30(3):617-626. PubMed ID: 26503641
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synergistic Targeting of the Regulatory and Catalytic Subunits of PI3Kδ in Mature B-cell Malignancies.
    Cooney JD; Lin AP; Jiang D; Wang L; Suhasini AN; Myers J; Qiu Z; Wölfler A; Sill H; Aguiar RCT
    Clin Cancer Res; 2018 Mar; 24(5):1103-1113. PubMed ID: 29246942
    [No Abstract]   [Full Text] [Related]  

  • 4. Apremilast is a selective PDE4 inhibitor with regulatory effects on innate immunity.
    Schafer PH; Parton A; Capone L; Cedzik D; Brady H; Evans JF; Man HW; Muller GW; Stirling DI; Chopra R
    Cell Signal; 2014 Sep; 26(9):2016-29. PubMed ID: 24882690
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Advances in the Development of Phosphodiesterase-4 Inhibitors.
    Peng T; Qi B; He J; Ke H; Shi J
    J Med Chem; 2020 Oct; 63(19):10594-10617. PubMed ID: 32255344
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phosphodiesterase-4 promotes proliferation and angiogenesis of lung cancer by crosstalk with HIF.
    Pullamsetti SS; Banat GA; Schmall A; Szibor M; Pomagruk D; Hänze J; Kolosionek E; Wilhelm J; Braun T; Grimminger F; Seeger W; Schermuly RT; Savai R
    Oncogene; 2013 Feb; 32(9):1121-34. PubMed ID: 22525277
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phosphodiesterase-4 inhibition augments human lung fibroblast vascular endothelial growth factor production induced by prostaglandin E2.
    Ikari J; Michalski JM; Iwasawa S; Gunji Y; Nogel S; Park JH; Nelson AJ; Farid M; Wang X; Schulte N; Basma H; Toews ML; Feghali-Bostwick C; Tenor H; Liu X; Rennard SI
    Am J Respir Cell Mol Biol; 2013 Oct; 49(4):571-81. PubMed ID: 23656623
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phosphodiesterase-4 enzyme as a therapeutic target in neurological disorders.
    Bhat A; Ray B; Mahalakshmi AM; Tuladhar S; Nandakumar DN; Srinivasan M; Essa MM; Chidambaram SB; Guillemin GJ; Sakharkar MK
    Pharmacol Res; 2020 Oct; 160():105078. PubMed ID: 32673703
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of type 4 cyclic nucleotide phosphodiesterase blocks intracellular TLR signaling in chronic lymphocytic leukemia and normal hematopoietic cells.
    Tan Y; Watkins AA; Freeman BB; Meyers JA; Rifkin IR; Lerner A
    J Immunol; 2015 Jan; 194(1):101-12. PubMed ID: 25416804
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Improvement of spatial memory function in APPswe/PS1dE9 mice after chronic inhibition of phosphodiesterase type 4D.
    Sierksma AS; van den Hove DL; Pfau F; Philippens M; Bruno O; Fedele E; Ricciarelli R; Steinbusch HW; Vanmierlo T; Prickaerts J
    Neuropharmacology; 2014 Feb; 77():120-30. PubMed ID: 24067928
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tumour growth inhibition and anti-angiogenic effects using curcumin correspond to combined PDE2 and PDE4 inhibition.
    Abusnina A; Keravis T; Zhou Q; Justiniano H; Lobstein A; Lugnier C
    Thromb Haemost; 2015 Feb; 113(2):319-28. PubMed ID: 25230992
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting phosphodiesterase 4 as a therapeutic strategy for cognitive improvement.
    Wei X; Yu G; Shen H; Luo Y; Shang T; Shen R; Xi M; Sun H
    Bioorg Chem; 2023 Jan; 130():106278. PubMed ID: 36413930
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Antipruritic mechanisms of topical E6005, a phosphodiesterase 4 inhibitor: inhibition of responses to proteinase-activated receptor 2 stimulation mediated by increase in intracellular cyclic AMP.
    Andoh T; Kuraishi Y
    J Dermatol Sci; 2014 Dec; 76(3):206-13. PubMed ID: 25458869
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Safety and Pharmacodynamics of the PDE4 Inhibitor Roflumilast in Advanced B-cell Malignancies.
    Kelly K; Mejia A; Suhasini AN; Lin AP; Kuhn J; Karnad AB; Weitman S; Aguiar RC
    Clin Cancer Res; 2017 Mar; 23(5):1186-1192. PubMed ID: 27542768
    [No Abstract]   [Full Text] [Related]  

  • 15. Phosphodiesterase-4 inhibition as a therapeutic strategy for metabolic disorders.
    Wu C; Rajagopalan S
    Obes Rev; 2016 May; 17(5):429-41. PubMed ID: 26997580
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Basal Spontaneous Firing of Rabbit Sinoatrial Node Cells Is Regulated by Dual Activation of PDEs (Phosphodiesterases) 3 and 4.
    Vinogradova TM; Sirenko S; Lukyanenko YO; Yang D; Tarasov KV; Lyashkov AE; Varghese NJ; Li Y; Chakir K; Ziman B; Lakatta EG
    Circ Arrhythm Electrophysiol; 2018 Jun; 11(6):e005896. PubMed ID: 29880528
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Phosphodiesterase 4 and its inhibitors in inflammatory diseases.
    Jin SL; Ding SL; Lin SC
    Chang Gung Med J; 2012; 35(3):197-210. PubMed ID: 22735051
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Newer treatments of psoriasis regarding IL-23 inhibitors, phosphodiesterase 4 inhibitors, and Janus kinase inhibitors.
    Wcisło-Dziadecka D; Zbiciak-Nylec M; Brzezińska-Wcisło L; Bebenek K; Kaźmierczak A
    Dermatol Ther; 2017 Nov; 30(6):. PubMed ID: 28994166
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Phosphodiesterase 4B is an effective therapeutic target in colorectal cancer.
    Kim DU; Kwak B; Kim SW
    Biochem Biophys Res Commun; 2019 Jan; 508(3):825-831. PubMed ID: 30528730
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phosphodiesterase 4B negatively regulates endotoxin-activated interleukin-1 receptor antagonist responses in macrophages.
    Yang JX; Hsieh KC; Chen YL; Lee CK; Conti M; Chuang TH; Wu CP; Jin SC
    Sci Rep; 2017 Apr; 7():46165. PubMed ID: 28383060
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.